2,210 research outputs found

    Innovation and Internationalization of Korean SMEs in the Textile and Footwear Industries

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    Innovation has been recognized as one of the factors that enhances firm internationalization, a vital route for the growth and survival of small and medium enterprises. Thus, it is important to identify antecedents of firm innovation and their impacts on SME internationalization for their long-term success. Accordingly, the present study examined a model of SME internationalization in which the causal relationships among entrepreneurial orientation, absorptive capacity, innovation (product, process, and marketing innovation), and internationalization were proposed. Analyses of 156 survey data collected from Korean SMEs exporting textiles, apparel, and footwear revealed that entrepreneurial orientation and absorptive capacity appeared to function as significant antecedents of product and process innovation. Among three dimensions of innovation, only process and marketing innovation positively affected internationalization. The study provides practical implications by asserting the importance of process and marketing innovation to increase firm internationalization

    Sequential whole cell conversion process for production of D-psicose and D- mannitol from D-fructose

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    Rare sugars, which exist only limited quantities naturally, have received considerable attention because of its various specific nutritional and biological functions. Likewise, D-psicose (D-ribo-2-hexulose or D-allulose), a C-3 epimer of D-fructose, has many uses which include reducing intra-abdominal fat accumulation, protecting pancreas beta-islets and improving insulin sensitivity. Especially, D-psicose has only 0.3% calories compared to sucrose, while it has 70% relative sweetness. Additionally, in 2012, D-psicose was approved as a food additive and designated as Generally Recognized As Safe (GRAS) by Food and Drug Administration (FDA). Despite such abundant advantages, there is no economical way of mass production of D-psicose. Recently, biological production of D-psicose from D-fructose using D-psicose 3-epimerase (DPE) has been developed. However, the conversion yield is below 30%, which causes an undesirable increase of purification cost because of the similar solubility of D-psicose and D-fructose. Thus, we addressed the problem by converting the residual fructose, after the reaction of D-psicose production, to D-mannitol, which has a low solubility. The sequential whole cell conversion reactions for D-psicose and D-mannitol allow a convenient and economic purification of both products. This work was supported by a grant from the Next-Generation BioGreen 21 Program (SSAC, grant#: PJ01106201), RDA, Korea. Reference 1) Carsten Bäumchen & Stephanie Bringer-Meyer (2007), Expression of glf Z.m. increases D-mannitol formation in whole cell biotransformation with resting cells of Corynebacterium glutamicum, Appl Microbiol Biotechnol 76(3):545–52. 2) Ortiz, M. E., Bleckwedel, J., Raya, R. R., & Mozzi, F. (2013). Biotechnological and in situ food production of polyols by lactic acid bacteria, Appl Microbiol Biotechnol 97:4713-4726 3) Park, Y., Oh, E. J., Jo, J., Jin, Y., & Seo, J. (2016). Recent advances in biological production of sugar alcohols. Curr Opin Biotechnol 37:105–113

    Assessment of genetic diversity and distance of three Cicuta virosa populations in South Korea

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    Cicuta virosa L. (Apiaceae) is a perennial emergent plant designated as an endangered species in South Korea. Accordingto the former records, only four natural habitats remain in South Korea. A former study suggested that three of four popu-lations (Pyeongchang: PC, Hoengseong: HS, Gunsan: GS) would be classified as different ecotypes based on their differentmorphological characteristics and life cycle under different environmental conditions. To evaluate this suggestion, weestimated genetic diversity in each population and distance among three populations by random amplification of poly-morphic DNA. Seven random primers generated a total of 61 different banding positions, 36 (59%) of them were polymor-phic. Neis gene diversity and the Shannon diversity index increased in the order of PC < HS < GS, which is the same orderof population size. In the two-dimensional (2D) plot of first two principal components in principal component analysiswith the presence of 61 loci, individuals could be grouped as three populations easily (proportion of variance = 0.6125).Neis genetic distance for the three populations showed the same tendency with the geographical distance within threepopulations. And it is also similar to the result of discriminant analysis with the morphological or life-cycle factors fromthe previous study. From the results, we concluded that three different populations of C. virosa should be classified asecotypes based on not only morphology and phenology but genetic differences in terms of diversity and distance as well.This study was supported by the Korea Ministry of En-vironment as The Eco-Innovation project, 416-111-010and by the Center for Aquatic Ecosystem Restoration(CAER) of the Eco-STAR project from the Ministry of En-vironment, Republic of Korea (MOE;08-III-12).OAIID:oai:osos.snu.ac.kr:snu2013-01/102/0000026049/7SEQ:7PERF_CD:SNU2013-01EVAL_ITEM_CD:102USER_ID:0000026049ADJUST_YN:NEMP_ID:A075900DEPT_CD:719CITE_RATE:0FILENAME:07_ecoenv_36(3)_jae geun kim_(205-210).pdfDEPT_NM:생물교육과EMAIL:[email protected]:

    Improved Surgical Technique for Heterotopic Aortic Transplantation in Mice

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    Transplant arteriosclerosis is the main limitation for long-term survival of solid organ transplant recipients. Animal models would provide invaluable tools to investigate the cellular and molecular mechanisms underlying the pathogenesis of transplant arteriosclerosis, as well as for studies with novel drugs and other reagents for the prevention of the disease. We have therefore developed a modified technique for aortic transplantation in mice. The central suture ligation of the recipient abdominal aorta allowed a simpler end-to-side anastomosis of a segment of the donor thoracic aorta into the infrarenal portion of the recipient abdominal aorta. Using this technique, the overall survival rate was 94%. We also observed typical aspects of chronic rejection of the aortic allografts not observed with isografts. Our new technique is relatively easy to perform and has a low incidence of thrombosis, thus being useful for studying various aspects of transplant arteriosclerosis
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