Dynamics of Social Influence on New Employees’ Use of Volitional IS: m-EHR Case in Hospital Setting

It is widely recognized that user resistance to Information Systems (IS) is particularly high in hospitals. In this regard, the future of mobile Electronic Health Record (m-EHR) systems is highly in question, mainly because their usage is not mandatory. Aiming to provide insights on how best to promote the use of m-EHR in hospitals, we investigate the effect of social influences on m-EHR usage by new doctors who recently began working at a hospital. Drawing upon the concept of organizational socialization and social influences, we hypothesize that coworkers’ m-EHR usage is positively associated with one by new doctors, and the strength of this association varies by the coworkers’ type of usage, by the hierarchical rankings of coworkers, and by the stage of socialization process in which the new doctors are situated. Our analyses using longitudinal m-EHR usage data (595,914 logs of 737 doctors) generally support our hypotheses

Oleate Prevents Palmitate-Induced Atrophy via Modulation of Mitochondrial ROS Production in Skeletal Myotubes

Accumulation of saturated fatty acids contributes to lipotoxicity-related insulin resistance and atrophy in skeletal muscle. Conversely, unsaturated fatty acids like docosahexaenoic acid were proven to preserve muscle mass. However, it is not known if the most common unsaturated oleate will protect skeletal myotubes against palmitate-mediated atrophy, and its specific mechanism remains to be elucidated. Therefore, we investigated the effects of oleate on atrophy-related factors in palmitate-conditioned myotubes. Exposure of myotubes to palmitate, but not to oleate, led to an induction of fragmented nuclei, myotube loss, atrophy, and mitochondrial superoxide in a dose-dependent manner. Treatment of oleate to myotubes attenuated production of palmitate-induced mitochondrial superoxide in a dose-dependent manner. The treatment of oleate or MitoTEMPO to palmitate-conditioned myotubes led to inhibition of palmitate-induced mRNA expression of proinflammatory (TNF-α and IL6), mitochondrial fission (Drp1 and Fis1), and atrophy markers (myostatin and atrogin1). In accordance with the gene expression data, our immunocytochemistry experiment demonstrated that oleate and MitoTEMPO prevented or attenuated palmitate-mediated myotube shrinkage. These results provide a mechanism indicating that oleate prevents palmitate-mediated atrophy via at least partial modulation of mitochondrial superoxide production

Design and Validation of the Bright Internet

Bright Internet research was launched as a core project of the AIS Bright ICT Initiative, which aims to build an ICT-enabled Bright Society. To facilitate research on the Bright Internet, we explicitly define the goals and principles of the Bright Internet, and review the evolution of its principles. The three goals of the Bright Internet are: the realization of preventive security, the provision of the freedom of anonymous expression for innocent netizens, and protection from the risk of privacy infringement that may be caused by preventive security schemes. We respecify design principles to fulfill these seemingly conflicting goals: origin responsibility, deliverer responsibility, identifiable anonymity, global collaboration, and privacy protection. Research for the Bright Internet is characterized by two perspectives: first, the Bright Internet adopts a preventive security paradigm in contrast to the current self-centric defensive protective security paradigm. Second, the target of research is the development and deployment of the Bright Internet on a global scale, which requires the design of technologies and protocols, policies and legislation, and international collaboration and global governance. This research contrasts with behavioral research on individuals and organizations in terms of the protective security paradigm. This paper proposes validation research concerning the principles of the Bright Internet using prevention motivation theory and analogical social norm theory, and demonstrates the need for a holistic and prescriptive design for a global scale information infrastructure, encompassing the constructs of technologies, policies and global collaborations. An important design issue concerns the business model design, which is capable of promoting the propagation of the Bright Internet platform through applications such as Bright Cloud Extended Networks and Bright E-mail platforms. Our research creates opportunities for prescriptive experimental research, and the various design and behavioral studies of the Bright Internet open new horizons toward our common goal of a bright future

Fade Lighting Control Method for Visual Comfort and Energy Saving

This study proposes a fade lighting control method to ensure the visual comfort of indoor occupants through gradual illuminance control while saving energy. The illuminance sensor measures the indoor illuminance and calculates the required illuminance for achieving a reference illuminance of 500 Lux. The control illuminance for each lighting is derived based on the required illuminance, and it is confirmed to fall within the threshold range of 20%. The illuminance values and time intervals for fade lighting control are calculated, ensuring that the amount of illuminance adjustment is divided by the size of the threshold range or less. In the performance evaluation, the proposed method (experimental group) was compared with the influence-based control method (control group). The result shows that this fade lighting control method minimizes the visual discomfort of occupants caused by sudden changes in lighting, and the same energy-saving of 11-42% is achieved as the control group