CDK4 Immunohistochemistry Results According to Tumor Recurrence.

<p>WD, well-differentiated; DD, dedifferentiated; IHC immunohistochemistry.</p

Quantitative real-time PCR results of <i>CDK4</i> amplification by a) well-differentiated (WD) and dedifferentiated (DD) liposarcomas: amplification levels were not different between the two histologic subtypes.

<p>Quantitative real-time PCR results of <i>CDK4</i> amplification in <b>b)</b> WD and <b>c)</b> DD liposarcomas according to tumor recurrence: amplification was higher in WD liposarcomas with recurrence after surgical resection, but not different in DD liposarcomas regardless of tumor recurrence.</p

Quantitative real-time PCR results of <i>MDM2</i> amplification according to a) tumor recurrence, and b) histologic subtype: <i>MDM2</i> amplification levels were not different according to tumor recurrence or histologic subtype.

<p>Quantitative real-time PCR results of <i>MDM2</i> amplification according to a) tumor recurrence, and b) histologic subtype: <i>MDM2</i> amplification levels were not different according to tumor recurrence or histologic subtype.</p

Predictors of Recurrence-free Survival for Well-differentiated Liposarcoma in Univariate and Multivariate Analyses.

<p>HR, hazard ratio; CI, confidence interval.</p

Overall patient survival, a), after surgical resection for well-differentiated and dedifferentiated liposarcoma of the abdomen, and b) Patient survival stratified by histologic subtype of liposarcoma.

<p>Well-differentiated liposarcoma group show better survival compared to dedifferentiated liposarcoma group (p<0.05).</p

Clinicopathologic characteristics of well-differentiated and dedifferentiated liposarcomas.

<p>*p<0.05,</p><p>**p<0.01.</p

Distant metastasis of abdominal dedifferentiated liposarcomas.

<p>Distant metastasis of abdominal dedifferentiated liposarcomas.</p

CDK4 immunohistochemistry staining.

<p><b>A.</b> CDK4(−) well-differentiated liposarcoma, <b>B.</b> CDK4(+) well-differentiated liposarcoma, <b>C.</b> CDK4(+) dedifferentiated liposarcoma.</p

Locoregional recurrence of abdominal well-differentiated and dedifferentiated liposarcomas.

<p>Locoregional recurrence of abdominal well-differentiated and dedifferentiated liposarcomas.</p

Synopsis of the patient inclusion and exclusion process.

<p>(WD, well-differentiated; DD, dedifferentiated; LPS, liposarcoma).</p