Slim ruimtegebruik door hergebruik en omkeerbaar ruimtegebruik: eindrapport

In het kader van het Beleidsplan Ruimte Vlaanderen 2020-2050 wordt het uitgangspunt van duurzame en ruimtelijke ontwikkeling vertaald naar de begrippen ‘slim’ en ‘zorgvuldig’ ruimtegebruik. Dit onderzoek bestaat erin mogelijkheden tot hergebruik en omkeerbaar ruimtegebruik te analyseren, te begroten en bespreekbaar te maken in het ruimtelijk beleid

In vitro percutaneous penetration through hairless rat skin: influence of temperature, vehicle and penetration enhancers

Theoretically, a positive relation is expected between skin temperature and the percutaneous penetration of topically applied substances. The aim of the present study was to evaluate the influence of the temperature on the in vitro percutaneous penetration of dihydrotestosterone. Hairless rat skin was mounted in static diffusion cells placed in a water bath at different temperatures (28.6, 35.1 and 38.2 degrees C, respectively). Different vehicles were tested as well as the addition of penetration promoting molecules such as oleic acid and limonene. A saline buffer was used as the receptor phase. Penetration through the skin was evaluated by means of scintillation counting of the radiolabelled dihydrotestosterone. Experiments were followed for a period of 29 h. The total amount of penetrant, dihydrotestosterone, as well as the flux, were calculated from these kinetics. Our results demonstrate a temperature effect with the highest penetration at 38.2 degrees C. The vehicle was also found to influence the penetration of dihydrotestosterone in a significant way. Furthermore, limonene presented better penetration promoting properties compared with oleic acid

Clinical and biologic evaluation of ovarian function in women treated by bone marrow transplantation for various indications during childhood or adolescence.

To evaluate which factors determine premature ovarian failure after bone marrow transplantation (BMT) during childhood and adolescence

Does singing enhance cooperation more than speaking does? A global experimental Stage 1 Registered Report

The evolution of music, language, and cooperation have been debated since before Darwin. The social bonding hypothesis proposes that these phenomena may be interlinked: musicality may have facilitated the evolution of group cooperation beyond the possibilities of spoken language. Although dozens of experimental studies have shown that synchronised rhythms can promote cooperation, it is unclear whether synchronous singing enhances cooperation relative to spoken language, particularly across diverse societies that differ in their musical/linguistic rhythms and social organisation. Here, we propose a Registered Report to test this hypothesis through a global experiment in diverse languages aiming to collect data from 1500 participants across 50 sites. The social bonding hypothesis predicts that cooperation will increase more after synchronous singing than after spoken (sequential) conversation or (simultaneous) recitation, while alternative hypotheses predict that song will not increase cooperation relative to speech. Regardless of outcome, these results will provide an unprecedented understanding of cross-cultural relationships between music, language, and cooperation