Risk factors associated with arterial hypertension in patients with systemic lupus erythematosus. Holguín, Cuba

Introduction: The presence of arterial hypertension in patients with systemic lupus erythematosus is a health problem that has not been studied in Holguín. Objective: To determine the cardiovascular risk factors associated with hypertension in patients with systemic lupus erythematosus. Material and Methods: A cross-sectional study was conducted. The universe was composed of 193 patients with lupus who were treated in the Rheumatology Consultation of the Clinical-Surgical Hospital of Holguín from March 3, 2014 to January 1, 2015. The sample was made up of 81 patients who were randomly selected according to a 95 % confidence interval, a population size of 193, an estimated proportion of arterial hypertension of 0,20, a precision of a 7 %, and a design effect of 1.  The recommendations of the American College of Rheumatology were followed for the diagnosis of lupus erythematosus, and national guidelines were used for the diagnosis of hypertension.  Clinical, anthropometric, and laboratory variables were determined. Odds Ratio (OR), and 95 % confidence intervals (IC95%) for risk determined factors were. Results: The risk factors associated with hypertension in patients with lupus erythematosus are: age (OR=1,04; IC95%:1,01-1,08), age of the lupus onset (OR=1,04; IC95%:1,01-1,08), diabetes mellitus (OR=8,50; IC95%:1,63-44,33), metabolic syndrome (OR=5,09; IC95%:1,87-13,84), hyperuricemia (OR=4,08; IC95%:1,07-15,44), and microalbuminuria (OR=19,81; IC95%:4,24-92,39). Conclusions: The patients with systemic lupus erythematosus presented cardiovascular risk factors associated with arterial hypertension, which are identifiable in the primary health care with variables of relatively easy realization. Keywords: systemic lupus erythematosus, metabolic syndrome, hypertension, risk factors, adults.</p

Risk factors associated with arterial hypertension in patients with Systemic lupus erythematous. Holguín, Cuba

Introduction: The presence of hypertension in patients with systemic lupus erythematous is a health problem that has not been studied in Holguín. Objective:To determine the cardiovascular risk factors associated with hypertension in patients with systemic lupus erythematous. Material and Methods: A cross-sectional study was conducted. The universe was composed of 193 patients with lupus who were treated in the Rheumatology consultation of the Clinical-Surgical Hospital of Holguín from March 3, 2014 to January 1, 2015.  The sample was made up of 81 patients who were randomly selected according to a 95 % confidence interval, a population size of 193, an estimated proportion of arterial hypertension of 0,20, a precision of a 7 %, and a design effect of 1.  The recommendations of the American College of Rheumatology were followed for the diagnosis of lupus erythematous, and national guidelines were used for the diagnosis of hypertension.  Clinical, anthropometric, and laboratory variables were determined.  Odds Ratio (OR), and 95 % (IC95%) confidence intervals for risk factors were determined. Results: The risk factors associated with hypertension in patients with lupus erythematous are: age (OR=1,04; IC95%:1,01-1,08), age of the lupus onset (OR=1,04; IC95%:1,01-1,08), diabetes mellitus (OR=8,50; IC95%:1,63-44,33), metabolic syndrome (OR=5,09; IC95%:1,87-13,84), hyperuricemia (OR=4,08; IC95%:1,07-15,44), and microalbuminuria (OR=19,81; IC95%:4,24-92,39). Conclusions:The patients with systemic lupus erythematous presented cardiovascular risk factors associated with hypertension, which are identifiable in the primary health care with variables of relatively easy realization. Keywords:systemic lupus erythematous, metabolic syndrome, hypertension, risk factors, adults.</p

Prevalence of hypertriglyceridemia and cardiovascular risk factors in students from the University of Medical Sciences. Holguin, 2014-2015

Foundation: Detecting high plasma triglyceride concentrations in children, teenagers and young people is of great importance to prevent future cardiovascular events.Objective: To determine the prevalence of hypertriglyceridemia and cardivascular risk factors associated to medical students.Methods: cross study, with a period of random sampling of 776 students registered during the academic course 2014-2015, in first year medical studies at the University of Medical Sciences Holguin, Cuba. In the sample of 242 students it was analyzed the presence of hypertriglyceridemia related to the variables: age, sex, arterial pressure, anthropometric measurements, laboratory measurements and associated risk factors. The Odd Ratios and the confidence intervals for risk factors were determined. The logistic regression analysis was done with EPIDAT 4,1 with a level of significance of 5 %.Results: The prevalence of hypertriglyceridemia was 30.58%, without differences between sexes. The prevalence of overweight, obesity, weight excess, abdominal obesity, arterial hypertension, high density lipoproteines- low cholesterol, and metabolic syndrome were  15,70 %, 4,13 %, 19,83 %, 22,31 %, 10,74 %, 3,31 %, 23,14 %, 8,26 % y 8,26 %, respectively. The associated significant risk factors metabolic syndrome, supraileac fold, high density lipoproteins- low cholesterol and glucemia.Conclusion: The prevalence rate of hypertriglyceridemia and associated risk factors were relatively high in university students apparently healthy.</p

Factores de riesgo asociados a hipertensión arterial en pacientes con lupus eritematoso sistémico. Holguín, Cuba

Introduction: The presence of hypertension in patients with systemic lupus erythematous is a health problem that has not been studied in Holguín. Objective:To determine the cardiovascular risk factors associated with hypertension in patients with systemic lupus erythematous. Material and Methods: A cross-sectional study was conducted. The universe was composed of 193 patients with lupus who were treated in the Rheumatology consultation of the Clinical-Surgical Hospital of Holguín from March 3, 2014 to January 1, 2015.  The sample was made up of 81 patients who were randomly selected according to a 95 % confidence interval, a population size of 193, an estimated proportion of arterial hypertension of 0,20, a precision of a 7 %, and a design effect of 1.  The recommendations of the American College of Rheumatology were followed for the diagnosis of lupus erythematous, and national guidelines were used for the diagnosis of hypertension.  Clinical, anthropometric, and laboratory variables were determined.  Odds Ratio (OR), and 95 % (IC95%) confidence intervals for risk factors were determined. Results: The risk factors associated with hypertension in patients with lupus erythematous are: age (OR=1,04; IC95%:1,01-1,08), age of the lupus onset (OR=1,04; IC95%:1,01-1,08), diabetes mellitus (OR=8,50; IC95%:1,63-44,33), metabolic syndrome (OR=5,09; IC95%:1,87-13,84), hyperuricemia (OR=4,08; IC95%:1,07-15,44), and microalbuminuria (OR=19,81; IC95%:4,24-92,39). Conclusions:The patients with systemic lupus erythematous presented cardiovascular risk factors associated with hypertension, which are identifiable in the primary health care with variables of relatively easy realization. Keywords:systemic lupus erythematous, metabolic syndrome, hypertension, risk factors, adults.Introducción: La presencia de hipertensión arterial en pacientes con lupus eritematoso sistémico constituye un problema de salud no estudiado en Holguín. Objetivo: Determinar factores de riesgo cardiovascular asociados a la hipertensión arterial en pacientes con lupus eritematoso sistémico. Material y Métodos: Estudio transversal de un universo de 193 pacientes con lupus atendidos en la consulta de Reumatología del Hospital Clínico Quirúrgico de Holguín desde el 3 de marzo de 2014 al 1 de enero de 2015. La muestra de 81 pacientes seleccionados por muestreo aleatorio simple según nivel de confianza de 95%, tamaño poblacional de 193, proporción estimada de hipertensión arterial de 0,20, precisión de 7% y efecto de diseño de 1. Para el diagnóstico de lupus eritematoso se siguieron las recomendaciones de American College of Rheumatology y de la hipertensión arterial por las guías nacionales. Se determinaron variables clínicas, antropométricas y de laboratorio. Se determinaron Odds Ratio (OR) e intervalos de confianza de 95% (IC95%) de los factores de riesgo. Resultados: Los factores de riesgo asociados a la hipertensión en pacientes con lupus son edad (OR=1,04; IC95%:1,01-1,08), edad de debut del lupus (OR=1,04; IC95%:1,01-1,08), diabetes mellitus (OR=8,50; IC95%:1,63-44,33),  síndrome metabólico (OR=5,09; IC95%:1,87-13,84), hiperuricemia (OR=4,08; IC95%:1,07-15,44) y microalbuminuria (OR=19,81; IC95%:4,24-92,39). Conclusiones: Los pacientes con lupus eritematoso sistémico presentaron factores de riesgo cardiovascular asociados a la hipertensión arterial, identificables en la atención primaria de salud con variables de relativa fácil realización.Palabras claves: Lupus eritematoso sistémico, síndrome metabólico, hipertensión arterial, factores de riesgo, adultos

Comportamiento clínico epidemiológico del síndrome metabólico en pacientes con lupus eritematoso sistémico

Introducción: la presencia de síndrome metabólico en pacientes con lupus eritematoso sistémico constituye un problema de salud no bien estudiado en Holguín.Objetivo: caracterizar clínica y epidemiológicamente al síndrome metabólico  en pacientes con lupus eritematoso sistémico.Métodos: estudio transversal de un universo de 193 pacientes con lupus atendidos en la consulta de Reumatología del Hospital Clínico Quirúrgico de Holguín desde el 03/02/2014 hasta el 01/12/2015. La muestra de 81 pacientes seleccionados por muestreo aleatorio simple según nivel de confianza de 95%, tamaño poblacional de 193, proporción estimada de SM de 0,20, precisión de 7 % y efecto de diseño de 1. Para el diagnóstico de lupus eritematoso se siguieron las recomendaciones de American College of Rheumatology y el SM se diagnosticó por criterios Adult Treatment Panel III. Se determinaron variables clínicas, antropométricas y de laboratorio.Resultados: no existieron diferencias significativas entre la edad de diagnóstico de la enfermedad, el tiempo de evolución del lupus y el tiempo de uso de esteroides entre los pacientes con síndromemetabólico y sin síndrome. Los factores de riesgo de síndrome metabólico en pacientes con lupus fueron la menopausia, hipertensión, obesidad, obesidad abdominal, hipertrigliceridemia, hipercolesterolemia, LDL-colesterol alto, hiperuricemia, microalbuminuria positiva, índices aterogénicos altos e índice cintura/estatura alto; no constituyeron factores asociados  el hábito de fumar, diabetes mellitus e hipotiroidismo.Conclusiones: los pacientes con síndrome metabólico y lupus presentan numerosos factores de riesgo cardiovascular, identificables en la atención primaria de salud con variables de relativa fácil realización

Prevalence of hypertriglyceridemia and cardiovascular risk factors in students from the University of Medical Sciences. Holguin, 2014-2015

Foundation: Detecting high plasma triglyceride concentrations in children, teenagers and young people is of great importance to prevent future cardiovascular events.Objective: To determine the prevalence of hypertriglyceridemia and cardivascular risk factors associated to medical students.Methods: cross study, with a period of random sampling of 776 students registered during the academic course 2014-2015, in first year medical studies at the University of Medical Sciences Holguin, Cuba. In the sample of 242 students it was analyzed the presence of hypertriglyceridemia related to the variables: age, sex, arterial pressure, anthropometric measurements, laboratory measurements and associated risk factors. The Odd Ratios and the confidence intervals for risk factors were determined. The logistic regression analysis was done with EPIDAT 4,1 with a level of significance of 5 %.Results: The prevalence of hypertriglyceridemia was 30.58%, without differences between sexes. The prevalence of overweight, obesity, weight excess, abdominal obesity, arterial hypertension, high density lipoproteines- low cholesterol, and metabolic syndrome were  15,70 %, 4,13 %, 19,83 %, 22,31 %, 10,74 %, 3,31 %, 23,14 %, 8,26 % y 8,26 %, respectively. The associated significant risk factors metabolic syndrome, supraileac fold, high density lipoproteins- low cholesterol and glucemia.Conclusion: The prevalence rate of hypertriglyceridemia and associated risk factors were relatively high in university students apparently healthy.</p