78 research outputs found
KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not?
In this focused review, we address the role of the kallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), in the regulation of angiogenesis. Early studies suggest that KLK3 is able to inhibit angiogenic processes, which is most likely dependent on its proteolytic activity. However, more recent evidence suggests that KLK3 may also have an opposite role, mediated by the ability of KLK3 to activate the (lymph)angiogenic vascular endothelial growth factors VEGF-C and VEGF-D, further discussed in the review
Determining inorganic and organic phosphorus
The original version of this chapter was revised. The correction to this chapter is available at https://doi.org/10.1007/7651_2019_253Phosphorus (P) is a macronutrient for all microalgal species, and the main form of uptake is as orthophosphate (PO4). In this chapter we present a colorimetric method for determining the PO4 concentration and dissolved organic phosphorus (DOP) based on total phosphorus (TP) measurements. We also describe a method for determining particulate organic phosphorus (POP) based on the same principles.Peer reviewe
KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not?
In this focused review, we address the role of the kallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), in the regulation of angiogenesis. Early studies suggest that KLK3 is able to inhibit angiogenic processes, which is most likely dependent on its proteolytic activity. However, more recent evidence suggests that KLK3 may also have an opposite role, mediated by the ability of KLK3 to activate the (lymph)angiogenic vascular endothelial growth factors VEGF-C and VEGF-D, further discussed in the review
Determining dissolved and biogenic silica
Most algae do not use silicon in any form with one notable exception, diatoms. Silicon is a major constituents of diatoms. Diatoms are characterized by high growth rates and are often one of the key groups in forming algal blooms in natural waters, and as such it is an interesting group for cultivation. In this chapter we present methods for determining dissolved silica (DSi) and biogenic silica (BSi), oxide forms of silicon, based on colorimetric methods. BSi is determined after filtration and alkaline digestion.Peer reviewe
Determining inorganic and organic nitrogen
Nitrogen (N) is one of the key nutrients for algal growth and is an integral part of many cellular components, for example in proteins. Being able to determine the inorganic and organic pools of N is consequently critical for algal cultivation. In this chapter we present the methods we use for determining dissolved inorganic nitrogen (DIN), dissolved organic nitrogen (DON) and particulate organic nitrogen (PON). The methods presented here for DIN rely on colorimetric methods and those of DON and PON on filtration and high temperature catalytic oxidation.Peer reviewe
Determining inorganic and organic carbon
Carbon is the element which makes up the major fraction of lipids and carbohydrates, which could be used for making biofuel. It is therefore important to provide enough carbon and also follow the flow into particulate organic and potential loss to dissolved organic forms of carbon. Here we present methods for determining dissolved inorganic carbon, dissolved organic and particulate organic carbon.Peer reviewe
KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not?
In this focused review, we address the role of the kallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), in the regulation of angiogenesis. Early studies suggest that KLK3 is able to inhibit angiogenic processes, which is most likely dependent on its proteolytic activity. However, more recent evidence suggests that KLK3 may also have an opposite role, mediated by the ability of KLK3 to activate the (lymph)angiogenic vascular endothelial growth factors VEGF-C and VEGF-D, further discussed in the review.Peer reviewe
Total nitrogen determination by a spectrophotometric method
Being able to measure total nitrogen (TN) is important for following the nitrogen budget. In this chapter, we present the spectrophotometric method we use for determining TN. The method relies on oxidation and reduction steps, involving persulfate digestion of nitrogen compounds into nitrate followed by spectrophotometric determination.Peer reviewe
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