Results of 3,668 primary total hip replacements

Contains fulltext : 109388.pdf (publisher's version ) (Open Access)1 april 201

THE POPLITEAL PTERYGIUM SYNDROME - AN ANALYSIS OF 2 FAMILIES

The popliteal pterygium syndrome is characterized by multiple anomalies of the face, genito-urinary system and extremities with autosomal dominant inheritance with variable expression. Also sporadic cases probably based upon spontaneous mutation can be recognized. The plastic, orthopaedic, and maxillofacial surgeon should be aware of the variable nature of the syndrome and should consult a medical geneticist. A coordinated team approach appears to be most adequate for diagnosis, counselling and treatment

Mechanical properties of normal avascular and revascularizing cancellous bone : an animal experiment

No abstract

Incorporation of morsellized bone graft under controlled loading conditions. A new animal model in the goat

The aim of this study was to develop a new animal model in which we could assess the in vivo effects of mechanical stimuli in the incorporation process of impacted morsellized bone grafts. The subcutaneous pressure implant SPI was developed for use in the goat. This device can generate controlled loading conditions onto a fixed amount of bone graft in the distal femur. Twenty goats were divided into three groups: non-loaded, 2 or 4 MPa loads (1 Hz, 1 h/day). The goats were sacrificed after 3, 6 or 12 weeks. The results were documented by clinical observations, quantitative bone density from QCT-scanning and histomorphometry. Nine post-mortem knee specimens were prepared in a similar manner to the experimental knees to determine the reproducibility and mechanical stability of the grafting method. Three goats were lost due to complications, the others functioned clinically well. Histology showed invasion of the bone graft by a front of vascular fibrous tissue after which osteoclasts resorbed the dead bone graft, followed by woven bone apposition on the graft remnants. At 12 weeks the loaded grafts had transformed into a vital trabecular structure. QCT bone density measurements revealed persistently high densities in the 12-weeks 4 MPa specimens, but reduced densities in the 2 MPa and non-loaded specimens. Morphometrically, the mineralising surface was larger in the 4 MPa group (P = 0.02) and the incorporation and remodelling processes had advanced more rapidly in the 2 MPa specimens (P = 0.04). Although the numbers investigated in this study in each group were low, statistical differences were found in the amount of graft left after incorporation and in the apposition rate of the new bone. In the future this model will be used to study the incorporation potential of different types of bone graft and bone graft substitutes. [Journal Article; In English; England

Sugioka's osteotomy for femoral-head necrosis in young Caucasians.

Contains fulltext : 48153.pdf (publisher's version ) (Closed access)The transtrochanteric rotational osteotomy described by Sugioka is used to preserve the femoral head and to prevent secondary osteoarthritis in young patients with osteonecrosis of the femoral head. Several Japanese studies have shown favourable results, but European and American studies were disappointing. An explanation for these outcomes may be that the original protocol was not followed exactly. The objective of our study was to investigate this trans-trochanteric rotational osteotomy in Caucasian patients with osteonecrosis in which we followed the original method of Sugioka as closely as possible, including a 6-month period of non-weight bearing. We included 26 hips in 22 consecutive patients who were followed up for 8.7 (range 6.6-10) years. At review, 17 hips had been converted to total hip arthroplasty. The clinical survival rate was 56% after 7 years (95% CI 36-76%). The radiological survival rate was 54% after one year (95% CI 35-73%). Even after excluding the failures due to problems with osteosynthesis and infection, the results were not satisfactory and the osteoarthritic process was not delayed. Based on our results, we cannot recommend this technique as an alternative for total hip arthroplasty in Caucasians