State switching in Bi-doped La[sub 0.67]Ca[sub 0.33]MnO[sub 3] and the effects of current

Electronic transport and magnetic properties of La0.477Bi0.193Ca0.33MnO3 have been experimentally studied. Different resistive behaviors are observed in the cooling and warming processes. The system first stays at a high resistive state, and switches to a state of lower resistivity when it is cooled below a critical temperature. However, keeping the sample at a temperature below ;60 K, a relaxation to the high resistive state takes place. This process is current dependent, and the application of a large current slows down the relaxation greatly. There is a strong competition between the two resistive states, which causes a switch of the system between states. © 2002 American Institute of Physics.published_or_final_versio

Animal Agriculture in South Carolina

Livestock Production/Industries,

Mechanism of Electromigration Failure in Al Thin Film Interconnects Containing Sc

In order to understand the role of Sc on electromigration (EM) failure, Al interconnects with 0.1 and 0.3 wt.% Sc sere tested as a function of post-pattern annealing time. In response to the evolution of the line structure, the statistics of lifetime evolved. While the addition of Sc greatly reduces the rate of evolution of the failure statistics because the grain growth rate decreases, the MTF variation was found to be very similar to that of pure Al. These observations seem to show that Sc has little influence on the kinetics of Al EM; however, it has some influence on the EM resistance of the line since it is an efficient grain refiner. Unlike Cu in Al, Sc does not seem to migrate, which may explain its lack of influence on the kinetics of Al EM

Fall-related injury in the hospital

Background: 2 — 9% of adult patients who fall in the hospital suffer serious injury. There is little evidence-based literature to guide physicians when assessing hospitalized patients for fall-related injury. This study was designed to (1) identify demographic and/or clinical factors which predict serious fall-related injury among hospitalized adults, and (2) judge the adequacy of physician documentation related to adult patients who fell in the hospital. Methods: Nursing staff are required to report all hospital falls through our hospitals computerized Patient Safety Network (PSN). We performed a retrospective chart review of all PSN reported falls that occurred during 2010 in our 431-bed university acute care hospital. Patients less than18 years old, pregnant women, and prisoners were excluded. Results: Medical records were available for 286/293 (98%) of PSN-reported falls in 251 eligible patients. Falls occurred in 152 males (61%), and 99 females (39%). 48% of falls occurred while toileting. 25% (63/286) of falls were associated with injury, and 4% (11/286) with serious injury (laceration requiring closure or fracture). Compared to all fallers, patients with injury did not differ by gender (males 38/152 vs. females 25/99, p=0.96). Patients older than 64 years who fell were no more likely to suffer injury that younger adults (13/64 vs. 50/187, p = 0.31). In univariate analysis, patients who reported hitting their head, patients with pre-fall confusion, and patients who received narcotics on the day of fall were more likely to suffer injury (estimated odds ratios 6.04, 2.00 and 5.1, respectfully). In multivariate analysis, receiving a narcotic on the day of fall was the strongest predictor of injury (Table). 33% (21/63) of falls with injury had no physician documentation in the hospital record, and in only 21% (13/63) of cases, were falls with injury mentioned in the discharge summary. Conclusions: In this single-institution study, injury occurred in 25% of patients who fell, and serious injury in 4%. Compared to all falls, falls with injury did not vary by gender or age. Receiving a narcotic of the day of fall was the strongest predictor of injury. Physicians inconsistently provided medical record documentation of hospitalized patients who fell with injury.\u2

Narcotic administration and fall-related injury in the hospital: Implications for patient safety programs and providers

Objective: Identify factors that predict fall-related injury in hospitalized adults. Design: Retrospective cohort study. Setting: 435-bed university hospital. Participants: Inpatients with reported falls in 2010. Results: Medical records were available for 286/293 (98%) of reported falls in 251 patients. 25% (63/286) of falls were associated with injury, 4% (11/286) with serious injury. Compared to all fallers, patients with injury did not differ by gender or age. In univariate analysis, patients who reported hitting their head, had pre-fall confusion, or who received narcotics within 24 hours before falling were more likely to suffer injury (estimated odds ratios 6.04, 2.00 and 5.1, respectfully). In multivariate analysis, receiving a narcotic prior to falling was the strongest predictor of injury (estimated odds ratio 5.59; 95% confidence intervals 2.14 — 14.65, p \u3c0.001). Conclusions: In this single-institution study, 25% of patients who fell suffered injury and 4% serious injury. Neither age nor gender predicted fall-related injury. Recent narcotic administration was the strongest predictor of injury. Strategies to prevent fall-related injury in the hospital should target patients receiving narcotics. When evaluating inpatients who have fallen, providers should be especially vigilant about injury in patients who have pre-fall confusion, hit their head, or have received recent narcotics

Animal Models to Study Host-Bacteria Interactions Involved in Periodontitis

Animal models have distinct advantages because they can mimic cellular complexities that occur in humans in vivo and are often more accurate than in vitro studies that take place on plastic surfaces with limited numbers of cell types present. Furthermore, cause and effect relationships can be established by applying inhibitors or activators or through the use of genetically modified animals. Such gain or loss of function studies are often difficult to achieve in human clinical studies, particularly in obtaining target tissue due to important ethical considerations. Animal models in periodontal disease are particularly important at this point in the development of the scientific basis for understanding the predominant pathological processes. Periodontal disease can be broken down into discrete steps, each of which may be studied separately depending upon the animal model. These steps involve the development of a pathogenic biofilm, invasion of connective tissue by bacteria or their products, induction of a destructive host response in connective tissue and limitation of are pair process that follows tissue breakdown. Animal studies can test hypotheses related to each of these steps, and should be evaluated by their capacity to test a specific hypothesis rather than recapitulating all aspects of periodontal disease. Thus, each of the models described below can be adapted to test discrete components of the pathological process of periodontal disease, but not necessarily all of them