2,487 research outputs found
Pathways to meet critical success factors for local PPPs: The cases of urban transport infrastructure in Korean cities
Public-Private Partnerships (PPPs) have been utilized extensively in both developed and developing countries to provide various public services and infrastructure. The literature points to many common critical success factors, including a mature financial market, transparent regulatory framework, advanced technology, and people's acceptance of new forms, but those can vary from country to country. South Korea's mature market capitalist system and strong regulatory framework have led to somewhat successful infrastructure provision through PPPs at the national level, but as our two cases of urban transportation in the Seoul Metropolitan Area indicate, local-level PPPs have demonstrated mixed results. By elaborating on the factors that affect the outcomes of PPPs at the local level, we argue that under a relatively new local democracy, Korean cities are likely to be susceptible to producing unfair contracts mainly due to limited local fiscal authority and resources, opportunistic behavior of local politicians, an underdeveloped urban institutional framework for PPPs, and the rise of new conditions such as economic nationalism intermixed with speculative foreign investment. (C) 2016 Elsevier Ltd. All rights reserved.1
City-building and the role of urban development in South Korea's political and economic transitions
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 201-214).This dissertation bridges the fields of international development and urban studies to examine South Korea's city building and urban development processes, arguing that the interaction between urban and industrial policies has both followed and produced the country's astonishing macroeconomic development successes. The study starts by raising the question of how a Third- World city, Seoul, which served as a minor metropolis in a primarily rural country as late as 1970, rapidly became a modern megalopolis and global front-runner in terms of ambitious and pioneering urban investments. Although South Korea's successful industrialization could be a short answer to this question, the capital city's predominant growth becomes rather puzzling when considering that South Korea, in contrast to the Latin American cases, initially developed its major industrialization and spatial development policies to support regional development and decentralization instead of promoting urban concentration in the capital city. To explain this puzzle, I examine South Korea's key spatial development policies and city building projects over the course of its economic development trajectories, from the 1960s to the 2000s. In the process of re-examining South Korea's modern economic development history with an emphasis on space, I found that the South Korean state worked actively to develop synergies between spatial and economic development, thus fortifying its role as both an industrial and urban developmental state. At consecutive stages since the late 1960s, the South Korean state deployed a disciplinary, forward-looking, set of policies targeted toward creating synergy between urban investments and macroeconomic priorities, even as it worked hard to accommodate citizen concerns about consumption, property rights, and democratization. With an eye to both political stability and economic growth, the South Korean state ended up crafting a set of spatial policies that ended up produced novel inter- and intra-urban development patterns that stood in contrast to those pursued in many other countries of the global South. Seoul's developmental gains, both urban and macroeconomic, are thus explained as an outcome of a strong state's commitment to connecting spatial and economic priorities, and to its capacity to guide these synergies over time and across various territorial scales.by Yu Min Joo.Ph.D
Optical Coherence Tomographic Finding in a Case of Macular Coloboma
PURPOSE: To report the optical coherence tomography (OCT) findings in a patient with unilateral macular coloboma. METHODS: A 12-year-old male was presented with macular coloboma in the left eye. The optical coherence tomography was performed with fluorescein angiography (FA). RESULTS: The OCT revealed the crater-like depression in the macula, demonstrating atrophic neurosensory retina, and an absence of retinal pigment epithelium and choroid in the lesion. FA showed hypofluorescence corresponding to the size of the lesion in both early and late frames without leakage of dye at any stage. CONCLUSIONS: The OCT can be beneficial to confirm the diagnosis of macular coloboma
MMP-Inhibitory Effects of Flavonoid Glycosides from Edible Medicinal Halophyte Limonium tetragonum
Limonium tetragonum has been well-known for its antioxidative properties as a halophyte. This study investigated the antimetastasis effect of solvent-partitioned L. tetragonum extracts (LTEs) and isolated compounds on HT1080 mouse melanoma cell model with a focus on matrix metalloproteinase (MMP) activity and TIMP and MAPK pathways. Upregulation and stimulation of MMPs result in elevated degradation of extracellular matrix which is part of several complications such as metastasis, cirrhosis, and arthritis. The anti-MMP capacity of LTEs was confirmed by their MMP-inhibitory effects, regulation of MMP and TIMP expression, and suppression of MAPK pathway. Among all tested LTEs, 85% aq. MeOH and n-BuOH were found to be most active fractions which later yielded two known flavonoid glycosides, myricetin 3-galactoside and quercetin 3-o-beta-galactopyranoside. Anti-MMP potential of the compounds was confirmed by their ability to regulate MMP expression through inhibited MAPK pathway activation. These results suggested that L. tetragonum might serve as a potential source of bioactive substances with effective anti-MMP properties
Impact of Depression on Work Productivity and Its Improvement after Outpatient Treatment with Antidepressants
AbstractObjectiveDepressive disorders influence socioeconomic burden at both the individual and organizational levels. This study estimates the lost productive time (LPT) and its resulting cost among workers with major depressive disorder (MDD) compared with a comparison group. It also estimates the change in productivity after 8 weeks of outpatient psychiatric treatment with antidepressants.MethodsWorking patients diagnosed with MDD without other major physical or mental disorders were recruited (n = 102), along with age- and sex-matched healthy controls from the Seoul Metropolitan area (n = 91). The World Health Organization's Health and Work Performance Questionnaire and the Hamilton Rating Scale for Depression were utilized to measure productivity and severity of depression, respectively, at baseline and at 8 weeks of treatment.ResultsThe LPT from absenteeism and presenteeism (reduced performance while present at work) was significantly higher among the MDD group. Workers with MDD averaged costs due to LPT at 33.4% of their average annual salary, whereas the comparison group averaged costs of 2.5% of annual salary. After 8 weeks of treatment, absenteeism and clinical symptoms of depression were significantly reduced and associated with significant improvement in self-rated job performance (31.8%) or cost savings of $7508 per employee per year.ConclusionsWe confirmed that significant productivity loss arises from MDD and that this loss can be reduced with psychiatric intervention after a time period as short as 8 weeks. Mental health professionals should work with employers to devise a cost-effective system to provide workers with accessible quality care
Causes and effects of 2008 financial crisis
Beginning in the mid 2007’s the US financial market started to slide into the “worst financial crisis since the Great Depression of the early 1930’s” (Thakor, 2015: p.156). The domino effect of several events and occasions were leading first to a countrywide recession in the USA then later spreading globally. In the following this term paper will deal with the main causes and effects of 2008 financial crisis. Unlike other topics in literature there is no consensus about the question of guilt in this sense. Among economists there are different approaches to explain the main causes of the financial crisis
Mothers' perceptions of children's food behaviors: use of focus group interview study
Children's food behaviors have been expressed in a various ways because of recent changes in their family environment. Thus, this study was performed to investigate in-depth qualitative research on the mother's perception on children's food behaviors by focused group interview. This study was designed in four steps of planning, collection of participants, process, and analysis. Participants for the focus group interview were recruited and sampled from households with elementary school students in the Seoul and Gyeonggido areas. Groups were divided by total income and education expense levels. 1) High income household: It is better to improve currently existing web sites for nutrition education. 2) Mid income household: Easy, practical, and inexpensive off-line cooking class/nutrition education classes for mothers are needed. Nutrition programs for children should be developed through mass media and be promoted in the broadcasting circle. 3) Low income household: Motivation is required for mothers' education and the serious nutritional problems of children should be informed through mass media and home correspondence from school. And interesting educational materials should be developed for children to read whenever they want
No Association of Functional Polymorphisms in Methlylenetetrahydrofolate Reductase and the Risk and Minor Physical Anomalies of Schizophrenia in Korean Population
Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate metabolism, plays an important role in DNA methylation. It has been suggested that abnormal DNA methylation contributes to the pathogenesis of schizophrenia and congenital anomalies. The previous findings regarding the genetic relationship between MTHFR and schizophrenia are controversial. This study investigated the association of the two functional polymorphisms of MTHFR, C677T and A1298C, with the risk for schizophrenia. Furthermore, we conducted an updated meta-analysis on the two polymorphisms. In addition, we investigated the relationship between the polymorphisms and minor physical anomaly (MPA), which may represent neurodevelopmental aberrations in 201 schizophrenia patients and 350 normal control subjects. There was no significant association between either of the two polymorphisms and the risk of schizophrenia (chi-square = 0.001, df = 1, P = 0.971 for C677T; chi-square = 1.319, df = 1, P = 0.251 for A1298C). However, in meta-analysis, the C677T polymorphism showed a significant association in the combined and Asian populations (OR = 1.13, P = 0.005; OR = 1.21, P = 0.011, respectively) but not in the Korean and Caucasian populations alone. Neither polymorphism was associated with MPAs measured by the Waldrop scale (chi-square = 2.513, df = 2, P = 0.285). In conclusion, the present findings suggest that in the Korean population, the MTHFR polymorphisms are unlikely to be associated with the risk for schizophrenia and neurodevelopmental abnormalities related to schizophrenia
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