22 research outputs found
Pyrokinin β-Neuropeptide Affects Necrophoretic Behavior in Fire Ants (S. invicta), and Expression of β-NP in a Mycoinsecticide Increases Its Virulence
Fire ants are one of the world's most damaging invasive pests, with few means for their effective control. Although ecologically friendly alternatives to chemical pesticides such as the insecticidal fungus Beauveria bassiana have been suggested for the control of fire ant populations, their use has been limited due to the low virulence of the fungus and the length of time it takes to kill its target. We present a means of increasing the virulence of the fungal agent by expressing a fire ant neuropeptide. Expression of the fire ant (Solenopsis invicta) pyrokinin β -neuropeptide (β-NP) by B. bassiana increased fungal virulence six-fold towards fire ants, decreased the LT50, but did not affect virulence towards the lepidopteran, Galleria mellonella. Intriguingly, ants killed by the β-NP expressing fungus were disrupted in the removal of dead colony members, i.e. necrophoretic behavior. Furthermore, synthetic C-terminal amidated β-NP but not the non-amidated peptide had a dramatic effect on necrophoretic behavior. These data link chemical sensing of a specific peptide to a complex social behavior. Our results also confirm a new approach to insect control in which expression of host molecules in an insect pathogen can by exploited for target specific augmentation of virulence. The minimization of the development of potential insect resistance by our approach is discussed
Metastatic epidural spinal cord compression: current concepts and treatment
Metastatic epidural spinal cord compression (MESCC) is a medical emergency complicating the course of 5–10% of patients with cancer [1]. When diagnosis and treatment is early with the patient ambulatory prognosis for continued ambulation is good [2]. If the patient is nonambulatory or paraplegic, prognosis for meaningful recovery of motor and bladder function is markedly decreased. In the last decade, significant advances in the understanding, management and treatment of metastatic epidural spinal cord compression have occurred.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45378/1/11060_2005_Article_BF01051052.pd
Andalusite and Na- and Li-rich cordierite in the La Costa pluton, Sierras Pampeanas, Argentina: textural and chemical evidence for a magmatic origin
The La Costa pluton in the Sierra de Velasco
(NW Argentina) consists of S-type granitoids that can be
grouped into three igneous facies: the alkali-rich Santa
Cruz facies (SCF, SiO2 *67 wt%) distinguished by the
presence of andalusite and Na- and Li-rich cordierite
(Na2O = 1.55–1.77 wt% and Li2O = 0.14–0.66 wt%), the
Anillaco facies (SiO2 *74 wt%) with a significant proportion
of Mn-rich garnet, and the Anjullo´n facies (SiO2
*75 wt%) with abundant albitic plagioclase. The petrography,
mineral chemistry and whole-rock geochemistry of
the SCF are compatible with magmatic crystallization of
Na- and Li-rich cordierite, andalusite and muscovite from
the peraluminous magma under moderate P–T conditions
(*1.9 kbar and ca. 735C). The high Li content of cordierite
in the SCF is unusual for granitic rocks of intermediate
composition
Petrology and Geochemistry of El Chichón and Tacaná: Two Active, yet Contrasting Mexican Volcanoes
Distributions of natural radium and radon isotopes in the German Bight of the North Sea
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