The Effect of Phyllanthus Amarus Aqueous Extract on Blood Glucose in Non-Insulin Dependent Diabetic Patients

The glycaemic response to 124.5 ± 9.3 (mean ± SD) g of pancakes was monitored in 21 non-insulin dependent diabetic (NIDDM) patients while on oral hypoglycaemics, after a one week washout period and after a one week twice daily treatment with 100 ml of an aqueous extract from 12.5 g of powdered aerial parts of Phyllanthus amarus. After the one week washout period, fasting blood glucose (FBG) and postprandial blood glucose increased significantly compared to when on oral hypoglycaemics (P ≤ 0.05). After one week herbal treatment no hypoglycaemic activity was observed. Both FBG and postprandial blood glucose remained very similar to that recorded after the washout period (P > 0.05). Both liver and renal functions based on alanine transaminase (ALAT) and serum creatinine, respectively, were not significantly affected by the use of the extract. Although lymphocyte and monocyte levels were significantly decreased (P ≤ 0.05) and granulocyte level was significantly increased after treatment (P ≤ 0.05) overall total white blood cell (WBC) count and haemoglobin (Hb) were not significantly affected by the one week herbal treatment. We conclude that one week treatment with the aqueous extract of Phyllanthus amarus was incapable of lowering both FBG and postprandial blood glucose in untreated NIDDM patients

Islet cell autoantibodies in African patients with Type 1 and Type 2 diabetes in Dar es Salaam Tanzania: a cross sectional study-0

<p><b>Copyright information:</b></p><p>Taken from "Islet cell autoantibodies in African patients with Type 1 and Type 2 diabetes in Dar es Salaam Tanzania: a cross sectional study"</p><p>http://www.jautoimdis.com/content/4/1/4</p><p>Journal of Autoimmune Diseases 2007;4():4-4.</p><p>Published online 27 Oct 2007</p><p>PMCID:PMC2147002.</p><p></p>eafter dropped slightly. In patients with T2D the prevalence was lowest in the 1–2 year interval of the disease, and slightly increased thereafter. There was no inverse correlation between duration of disease and autoantibodies in the patients with T1D