Nature and nurture. Genetic and environmental factors on the relationship between back pain and sleep quality.

BACKGROUND: Chronic low back pain (LBP), neck pain (NP), and sleep quality (SQ) are genetically influenced. All three conditions frequently co-occur and shared genetic aetiology on a pairwise base has been reported. However, to our knowledge, no study has yet investigated if these three conditions are influenced by the same genetic and environmental factors and the extent and pattern of genetic overlap between them, hence the current research. METHODS: The sample included 2134 participants. Lifetime prevalence of NP and LBP were assessed through a dichotomous self-reported question derived from the Spanish National Health Survey. SQ was measured using the Pittsburgh Sleep Quality Index Questionnaire. A common pathway model with sleep quality and back pain as latent factors was fitted. RESULTS: Our results highlight that a latent back pain factor, including both NP and LBP, is explained by both genetic (41%) and environmental (59%) factors. There are also significant unique environmental factors for NP (33%) and LBP (37%) respectively. Yet, specific genetic factors were scant (9%) for NP and negligible for LBP (0%). Genetic and environmental factors affecting SQ only contribute with 3% and 5% of the variance, respectively, to the common latent back pain variable. CONCLUSIONS: NP and LBP share most of their genetic variance, while environmental effects show greater specificity for each of the back pain locations. Associations with SQ were of a limited magnitude. SIGNIFICANCE: Our results confirm a significant association between both chronic NP and LBP and sleep quality. Such relationship comprises both genetic and environmental factors, with a greater relative weight of the latter. A large part of the individual variance for chronic LBP and chronic NP can be accounted for by a latent common factor of 'back pain'. Genetic influences for LBP and NP were mainly shared. However, environmental influences were common for both problems and specific for each of them in similar magnitudes

Perspectives on interpersonal touch are related to subjective sleep quality

Affective touch has been reported for its calming effects; however, it is less clear whether touch is associated with sleep. Here, the relationship between different touch variables and self-reported sleep indicators was investigated. Data were extracted from the Touch Test, a cross-sectional survey conducted in 2020. Data from a sample of 15049 healthy adults from the UK (mean age = 56.13, SD = 13.8; 75.4% female) were analysed. Participants were asked to attribute positive, negative or no effects on sleep to hugs, strokes, massages, intimate touch, and sleep onset with and without touch. The time since last intentional touch, touch amount satisfaction, and childhood bed routine with hugs and kisses were assessed. Sleep quality, -duration, -latency, wake after sleep onset and diurnal preference were measured. Data were analysed using chi-square tests and logistic regressions. Affective touch before sleep was perceived to have positive effects on sleep. Touch recency emerged as a significant predictor for some sleep variables, with a longer timespan since last intentional touch relating to improved sleep quality, longer sleep duration, and shorter and fewer instances of waking up after sleep onset in some participants. Experiencing too much touch was related to lower sleep quality and higher instances of waking up after sleep onset. These findings highlight the importance of interpersonal touch for subjective sleep quality

Sleep and temperament in early childhood

Sleep and temperament represent key behaviours in early childhood that reflect underlying individual constitutional differences and influence each other, and many developmental processes over time. This chapter aims to provide the reader with a basic understanding of the early childhood temperament field including definitions, history, and measurement issues. An overview of the key findings in regards to early sleep behaviours and temperament interactions across the first five years of life is provided, and the important role of the parenting environment is briefly explained. While there remain a number of challenges to overcome in the field, two key areas are further developed here. Future work should aim to increase our understanding about why early sleep and temperament are linked, and about the mechanisms involved in transactional developmental systems involving sleep, temperament, genes, and the parenting environment. Multi-disciplinary and creative modelling approaches will be needed to advance the field which should seek to create translatable research findings for the early childhood health and education sectors. Research should contribute to identifying children at the highest risk of ongoing sleep and social-emotional adjustment problems, and address these with appropriately targeted prevention and intervention strategies that support parents, educators, and health practitioners in their roles