The effects of Δ9-tetrahydrocannabinol on the dopamine system

Δ(9)-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, is a pressing concern to global mental health. Patterns of use are changing drastically due to legalisation, availability of synthetic analogues (‘spice’), cannavaping and aggrandizements in the purported therapeutic effects of cannabis. Many of THC’s reinforcing effects are mediated by the dopamine system. Due to complex cannabinoid-dopamine interactions there is conflicting evidence from human and animal research fields. Acute THC causes increased dopamine release and neuron activity, whilst long-term use is associated with blunting of the dopamine system. Future research must examine the long-term and developmental dopaminergic effects of the drug

From Complicit Citizens to Potential Prey: State Imaginaries and Subjectivities in US War Resistance

The movements against the Vietnam and Iraq wars gave rise to analogous resistance efforts, in the form of draft resistance and counter-recruitment, respectively. Despite their many similarities, the draft resistance and counter-recruitment movements emerged in distinct historical eras marked by very different ‘state imaginaries’ or assumptions about the nature of the state and people’s relation to it. Drawing on original archival work, this paper excavates these state imaginaries and examines how they conditioned activists’ subjectivities in each era. More specifically, this paper argues that the 1960s were marked by an imaginary of the state based on consent, which positioned draft resisters as complicit citizens and engendered a sense of personal responsibility for the war. This state imaginary was displaced in the neoliberal era by an imaginary of the state as an alien and invasive force, which positioned counter-recruitment activists (or their children) as potential prey and impelled efforts at self-defense