Universal Relations for a Fermi Gas Close to a p-Wave Interaction Resonance

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Rapid sympathetic cooling to Fermi degeneracy on a chip

Neutral fermions present new opportunities for testing many-body condensed matter systems, realizing precision atom interferometry, producing ultra-cold molecules, and investigating fundamental forces. However, since their first observation, quantum degenerate Fermi gases (DFGs) have continued to be challenging to produce, and have been realized in only a handful of laboratories. In this Letter, we report the production of a DFG using a simple apparatus based on a microfabricated magnetic trap. Similar approaches applied to Bose-Einstein Condensation (BEC) of 87Rb have accelerated evaporative cooling and eliminated the need for multiple vacuum chambers. We demonstrate sympathetic cooling for the first time in a microtrap, and cool 40K to Fermi degeneracy in just six seconds -- faster than has been possible in conventional magnetic traps. To understand our sympathetic cooling trajectory, we measure the temperature dependence of the 40K-87Rb cross-section and observe its Ramsauer-Townsend reduction.Comment: 5 pages, 4 figures (v3: new collision data, improved atom number calibration, revised text, improved figures.

Characterisation of Innate Fungal Recognition in the Lung

The innate recognition of fungi by leukocytes is mediated by pattern recognition receptors (PRR), such as Dectin-1, and is thought to occur at the cell surface triggering intracellular signalling cascades which lead to the induction of protective host responses. In the lung, this recognition is aided by surfactant which also serves to maintain the balance between inflammation and pulmonary function, although the underlying mechanisms are unknown. Here we have explored pulmonary innate recognition of a variety of fungal particles, including zymosan, Candida albicans and Aspergillus fumigatus, and demonstrate that opsonisation with surfactant components can limit inflammation by reducing host-cell fungal interactions. However, we found that this opsonisation does not contribute directly to innate fungal recognition and that this process is mediated through non-opsonic PRRs, including Dectin-1. Moreover, we found that pulmonary inflammatory responses to resting Aspergillus conidia were initiated by these PRRs in acidified phagolysosomes, following the uptake of fungal particles by leukocytes. Our data therefore provides crucial new insights into the mechanisms by which surfactant can maintain pulmonary function in the face of microbial challenge, and defines the phagolysosome as a novel intracellular compartment involved in the innate sensing of extracellular pathogens in the lung

Patterned magnetic thin films for ultra high density recording

The areal bit density of magnetic disk recording has increased since 1990 60% per year and even in the last years 100%. Extrapolation of these rates leads to recording parameters not likely to be achieved without changes in the present way of storing hard disk data. One of the possible solutions is the development of so-called patterned magnetic media. Such media will also shift the superparamagnetic limit positively in comparison with the present thin film media. Theoretically, a bit density in the order of Tbits/in 2 may be possible by using this so-called discrete magnetic recording scheme. The patterned structures presented in this paper consist of a regular two-dimensional array of single domain dots with large uniaxial magnetic anisotropy and have been prepared from CoNi/Pt multilayers with strong intergranular exchange coupling and large perpendicular magnetic anisotropy. For the preparation of the patterned media, a patterning process based on Laser Interference Lithography method (LIL) and Ion Beam Etching has been developed. This technology provides the possibility to pattern 2-D arrays of submicron dots smaller than the critical size for the transition from multi to single domain. The smallest prepared dot sizes are 60 nm with a center-to-center dot spacing of 200 nm and thickness of 30 nm. The magnetic characterization of these dots showed that they are single domain with reasonable coercivity and good thermal stability. Micromagnetic simulations show that the single domain state is the lowest energy state for dots with a diameter below 75nm, which confirms the experimental observations

Impact of the Environment upon the Candida albicans Cell Wall and Resultant Effects upon Immune Surveillance

Acknowledgements This work was funded by a programme grant from the UK Medical Research Council [www.mrc.ac.uk: MR/M026663/1], and by PhD studentships from the University of Aberdeen to AP, DL. The work was also supported by the Medical Research Council Centre for Medical Mycology (MR/N006364/1) and by the Wellcome Trust [www.wellcome.ac.uk: 097377]. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.Postprin