12 research outputs found
A ruthenium(II) hydride carbonyl complex with 4-phenylpyrimidine as co-ligand
The reaction of [RuHCl(CO)(PPh3)3] with
4-phenylpyrimidine gave a new ruthenium(II) complex,
namely [RuHCl(CO)(PPh3)2(pyrim-4-Ph)]. The complex
has been studied by IR and UVâvis spectroscopy and by
X-ray crystallography. The molecular orbitals of the
complex have been calculated by density functional theory.
The spin-allowed singletâsinglet electronic transitions of
the complex have been calculated by time-dependent DFT,
and the UVâvis spectrum of the compound has been
discussed on this basis. The emission properties of the
complex were also studied
Molecular, spectroscopic, and magnetic properties of cobalt(II) complexes with heteroaromatic N(O)-donor ligands
New [Co(SCN)2(L)4/2] complexes, where
L = b-pic (1), pyCH2OH (2), py(CH2)3OH (3), 1,2,4-
triazolo[1,5-a]pyrimidine (4), [CoCl2(urotrop)2] (5), and
[Co(DMIM)3]Cl2 H2O (6) where urotrop = hexamethylenetetramine
and DMIM = 2,20-bis(4,5-dimethylimidazolyl)
were synthesized in simple reactions of CoCl2 6H2O
with ammonia thiocyanate and pyridine type ligands or
urotropine and diimidazolyl ligands with cobalt(II) chloride
in methanol solutions. The orthorhombic crystallization
for (1), (2), and (4), the monoclinic one for (3) and (5)
as well as the hexagonal one for (6) were found. The plots
of the overlap population density-of-states indicated nonbonding
character of the interactions between pyridine
derivatives ligands and cobalt(II) ions in the complexes
(1)â(4). The electronic spectra showed almost perfect
octahedral complex in the case of (6). The magnetic susceptibility
measurements revealed paramagnetic behavior
with low values of the CurieâWeiss temperature, positive
for complex (5) and negative for the other ones, although
the transition to collective magnetic state at low temperatures
for (4) and (5) was evidenced by an observation of
antiferromagnetic coupling with NeÂŽel temperature of 4.5 K
and the ferromagnetic one with Curie temperature of 10 K,
respectively
Synthesis and anticancer activity of long-chain isonicotinic ester ligand-containing arene ruthenium complexes and nanoparticles
Arene ruthenium complexes containing long-chain N-ligands L1 = NC5H4-4-COO-C6H4-4-O-(CH2)9-CH3 or L2 = NC5H4-4-COO-(CH2)10-O-C6H4-4-COO-C6H4-4-C6H4-4-CN derived from isonicotinic acid, of the type [(arene)Ru(L)Cl2] (arene = C6H6, L = L1: 1; arene = p-MeC6H4Pr i , L = L1: 2; arene = C6Me6, L = L1: 3; arene = C6H6, L = L2: 4; arene = p-MeC6H4Pr i , L = L2: 5; arene = C6Me6, L = L2: 6) have been synthesized from the corresponding [(arene)RuCl2]2 precursor with the long-chain N-ligand L in dichloromethane. Ruthenium nanoparticles stabilized by L1 have been prepared by the solvent-free reduction of 1 with hydrogen or by reducing [(arene)Ru(H2O)3]SO4 in ethanol in the presence of L1 with hydrogen. These complexes and nanoparticles show a high anticancer activity towards human ovarian cell lines, the highest cytotoxicity being obtained for complex 2 (IC50 = 2 ÎŒM for A2780 and 7 ÎŒM for A2780cisR