11 research outputs found

    Mobility and Ageing: a review of interactions between transport and technology from the perspective of older people

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    This chapter is an overview of the issues for older people in relation to transport and technology. I demonstrate that mobility and technology are intertwined in complex ways, and that non-transport technologies may impact older people’s experience and achievement of mobility. Understanding the nexus between mobility, information and communication technologies and older people can help us design accessible and acceptable technologies to support well-being and health in older age. This matters because new ICT is increasingly relied on to support service delivery in both the public and private sectors. Older people are heterogeneous, with different attitudes, levels of income and education affecting technology uptake. Age-related cognitive and physical impairments can also impact on technology adoption. The chapter concludes with how age-friendly design principles can support active ageing

    2020 Alzheimer's disease facts and figures

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    Solid-state nanopore sensors

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    Nanopore-based sensors have established themselves as a prominent tool for solution-based, single-molecule analysis of the key building blocks of life, including nucleic acids, proteins, glycans and a large pool of biomolecules that have an essential role in life and healthcare. The predominant molecular readout method is based on measuring the temporal fluctuations in the ionic current through the pore. Recent advances in materials science and surface chemistries have not only enabled more robust and sensitive devices but also facilitated alternative detection modalities based on field-effect transistors, quantum tunnelling and optical methods such as fluorescence and plasmonic sensing. In this Review, we discuss recent advances in nanopore fabrication and sensing strategies that endow nanopores not only with sensitivity but also with selectivity and high throughput, and highlight some of the challenges that still need to be addressed
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