2,564 research outputs found
Mice null for brush border myosin I assemble brush borders and lack an overt phenotype
published_or_final_versio
KSU Brass Faculty Recital
Enjoy a performance by the KSU brass faculty: Doug Lindsey, Mike Tiscione, Richard Williams, J.D. Handshoe, and Ryan Moser, all accompanied pianists Judith Cole and Eric Jenkins.https://digitalcommons.kennesaw.edu/musicprograms/2377/thumbnail.jp
Australia's coastal fisheries and farmed seafood: An ecological basis for determining sustainability
In response to consumer concerns about the sustainability of Australian-sourced seafood we derive a set of criteria within an explicit decision-process that can be used to determine whether locally farmed and wild-caught Australian seafood products meet standards of ecological sustainability and Ecologically Sustainable Development. These criteria substantially address the ecological deficiencies we identified in other systems commonly used for assessing seafood sustainability. The criteria address the issues that are relevant to local seafood production, and are populated with indicators (metrics) and benchmarks relevant to the Australian context. The indicators establish performance thresholds drawn from public domain data about the products, including observed empirical data and proxies, and include default decisions to be applied in the absence of adequate information. This decision structure is set within a peer-reviewed expert jury decision-making process. The criteria, decision process and decision outcomes from assessment of a number of pilot products were tested in a real seafood market (Melbourne), where we found a high level of producer, reseller and consumer acceptance of the judgements and ratings. The use of ecologically-derived standards results in several outcomes that differ from those of other seafood assessment systems, especially those assessments more focused on production standards, such as government, industry and NGO-supported programs, popularly used in Australia and worldwide. We conclude that despite high levels of uncertainty surrounding many of the population parameters, ecological patterns and processes, empirical cost-effective proxies can be used to reasonably estimate a form of sustainability that matches consumer interests/expectations for production of fresh local seafood. Despite the plethora of industry and government programs, there remains a significant but presently unmet consumer demand for ecologically-based, technically robust, independently derived, and readily available information about the local sustainability attributes of Australian wild-caught and farmed fresh seafood
Interstellar Dust Close to the Sun
The low density interstellar medium (ISM) close to the Sun and inside of the
heliosphere provides a unique laboratory for studying interstellar dust grains.
Grain characteristics in the nearby ISM are obtained from observations of
interstellar gas and dust inside of the heliosphere and the interstellar gas
towards nearby stars. Comparison between the gas composition and solar
abundances suggests that grains are dominated by olivines and possibly some
form of iron oxide. Measurements of the interstellar Ne/O ratio by the
Interstellar Boundary Explorer spacecraft indicate that a high fraction of
interstellar oxygen in the ISM must be depleted onto dust grains. Local
interstellar abundances are consistent with grain destruction in ~150 km/s
interstellar shocks, provided that the carbonaceous component is hydrogenated
amorphous carbon and carbon abundances are correct. Variations in relative
abundances of refractories in gas suggest variations in the history of grain
destruction in nearby ISM. The large observed grains, > 1 micron, may indicate
a nearby reservoir of denser ISM. Theoretical three-dimensional models of the
interaction between interstellar dust grains and the solar wind predict that
plumes of about 0.18 micron dust grains form around the heliosphere.Comment: 2011 AGOS Taiwan meeting; accepted for publication in Earth, Planets
and Spac
Viewpoint on Emv2, the onlhy endogenous ecotropic murine leukemia virus of C57BL/6 mice
Here I comment on the articles by Lee and colleagues (Retrovirology 2011, 8:82) and Lee and Cho (Retrovirology 2012, 9:23) dealing with an endogenous ecotropic mouse leukemia virus found in C57BL mice
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Symptoms predicting psychosocial impairment in bulimia nervosa
Purpose
The current study aimed to determine which particular eating disorder (ED) symptoms and related features, such as BMI and psychological distress, uniquely predict impairment in bulimia nervosa (BN).
Methods
Two hundred and twenty-two adults with BN completed questionnaires assessing ED symptoms, general psychological distress, and psychosocial impairment. Regression analyses were used to determine predictors which account for variance in impairment.
Results
Four variables emerged as significant predictors of psychosocial impairment: concerns with eating; concerns with weight and shape; dietary restraint; and general psychological distress.
Conclusions
Findings support previous work highlighting the importance of weight and shape concerns in determining ED-related impairment. Other ED symptoms, notably dietary restraint and concerns with eating, were also significant predictors as was psychological distress. Results suggest that cognitive aspects of EDs, in addition to psychological distress, may be more important determinants of impairment than behavioural symptoms, such as binge eating or purging
Preliminary study of the presence of antibodies against excretory-secretory antigens from protoscoleces of Echinococcus granulosus in dogs with intestinal echinococcosis
Critical review of the current and future challenges associated with advanced in vitro systems towards the study of nanoparticle (secondary) genotoxicity.
With the need to understand the potential biological impact of the plethora of nanoparticles (NPs) being manufactured for a wide range of potential human applications, due to their inevitable human exposure, research activities in the field of NP toxicology has grown exponentially over the last decade. Whilst such increased research efforts have elucidated an increasingly significant knowledge base pertaining to the potential human health hazard posed by NPs, understanding regarding the possibility for NPs to elicit genotoxicity is limited. In vivo models are unable to adequately discriminate between the specific modes of action associated with the onset of genotoxicity. Additionally, in line with the recent European directives, there is an inherent need to move away from invasive animal testing strategies. Thus, in vitro systems are an important tool for expanding our mechanistic insight into NP genotoxicity. Yet uncertainty remains concerning their validity and specificity for this purpose due to the unique challenges presented when correlating NP behaviour in vitro and in vivo This review therefore highlights the current state of the art in advanced in vitro systems and their specific advantages and disadvantages from a NP genotoxicity testing perspective. Key indicators will be given related to how these systems might be used or improved to enhance understanding of NP genotoxicity
Evaluation of the benefits, harms and costâeffectiveness of potential alternatives to iFOBT testing for colorectal cancer screening in Australia
The Australian National Bowel Cancer Screening Program (NBCSP) will fully rollâout 2âyearly screening using the immunochemical Faecal Occult Blood Testing (iFOBT) in people aged 50 to 74 years by 2020. In this study, we aimed to estimate the comparative health benefits, harms, and costâeffectiveness of screening with iFOBT, versus other potential alternative or adjunctive technologies. A comprehensive validated microsimulation model, Policy1âBowel, was used to simulate a total of 13 screening approaches involving use of iFOBT, colonoscopy, sigmoidoscopy, computed tomographic colonography (CTC), faecal DNA (fDNA) and plasma DNA (pDNA), in people aged 50 to 74 years. All strategies were evaluated in three scenarios: (i) perfect adherence, (ii) high (but imperfect) adherence, and (iii) low adherence. When assuming perfect adherence, the most effective strategies involved using iFOBT (annually, or biennially with/without adjunct sigmoidoscopy either at 50, or at 54, 64 and 74 years for individuals with negative iFOBT), or colonoscopy (10âyearly, or onceâoff at 50 years combined with biennial iFOBT). Colorectal cancer incidence (mortality) reductions for these strategies were 51â67(74â80)% in comparison with no screening; 2âyearly iFOBT screening (i.e. the NBCSP) would be associated with reductions of 51(74)%. Only 2âyearly iFOBT screening was found to be costâeffective in all scenarios in context of an indicative willingnessâtoâpay threshold of A2,984/LYSâA$5,981/LYS (depending on adherence). The fully rolledâout NBCSP is highly costâeffective, and is also one of the most effective approaches for bowel cancer screening in Australia
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