17 research outputs found
Precision Measurement of the Newtonian Gravitational Constant Using Cold Atoms
About 300 experiments have tried to determine the value of the Newtonian
gravitational constant, G, so far, but large discrepancies in the results have
made it impossible to know its value precisely. The weakness of the
gravitational interaction and the impossibility of shielding the effects of
gravity make it very difficult to measure G while keeping systematic effects
under control. Most previous experiments performed were based on the torsion
pendulum or torsion balance scheme as in the experiment by Cavendish in 1798,
and in all cases macroscopic masses were used. Here we report the precise
determination of G using laser-cooled atoms and quantum interferometry. We
obtain the value G=6.67191(99) x 10^(-11) m^3 kg^(-1) s^(-2) with a relative
uncertainty of 150 parts per million (the combined standard uncertainty is
given in parentheses). Our value differs by 1.5 combined standard deviations
from the current recommended value of the Committee on Data for Science and
Technology. A conceptually different experiment such as ours helps to identify
the systematic errors that have proved elusive in previous experiments, thus
improving the confidence in the value of G. There is no definitive relationship
between G and the other fundamental constants, and there is no theoretical
prediction for its value, against which to test experimental results. Improving
the precision with which we know G has not only a pure metrological interest,
but is also important because of the key role that G has in theories of
gravitation, cosmology, particle physics and astrophysics and in geophysical
models.Comment: 3 figures, 1 tabl
Evolutionary explanations in medical and health profession courses: are you answering your students' "why" questions?
BACKGROUND: Medical and pre-professional health students ask questions about human health that can be answered in two ways, by giving proximate and evolutionary explanations. Proximate explanations, most common in textbooks and classes, describe the immediate scientifically known biological mechanisms of anatomical characteristics or physiological processes. These explanations are necessary but insufficient. They can be complemented with evolutionary explanations that describe the evolutionary processes and principles that have resulted in human biology we study today. The main goal of the science of Darwinian Medicine is to investigate human disease, disorders, and medical complications from an evolutionary perspective. DISCUSSION: This paper contrasts the differences between these two types of explanations by describing principles of natural selection that underlie medical questions. Thus, why is human birth complicated? Why does sickle cell anemia exist? Why do we show symptoms like fever, diarrhea, and coughing when we have infection? Why do we suffer from ubiquitous age-related diseases like arteriosclerosis, Alzheimer's and others? Why are chronic diseases like type II diabetes and obesity so prevalent in modern society? Why hasn't natural selection eliminated the genes that cause common genetic diseases like hemochromatosis, cystic fibrosis, Tay sachs, PKU and others? SUMMARY: In giving students evolutionary explanations professors should underscore principles of natural selection, since these can be generalized for the analysis of many medical questions. From a research perspective, natural selection seems central to leading hypotheses of obesity and type II diabetes and might very well explain the occurrence of certain common genetic diseases like cystic fibrosis, hemochromatosis, Tay sachs, Fragile X syndrome, G6PD and others because of their compensating advantages. Furthermore, armed with evolutionary explanations, health care professionals can bring practical benefits to patients by treating their symptoms of infection more specifically and judiciously. They might also help curtail the evolutionary arms race between pathogens and antibiotic defenses
Effects of Race, Ethnicity, and Gender on Surgical Mortality in Hypoplastic Left Heart Syndrome
Maximizing gravitational acceleration measurement accuracy by tuning the interaction time between atoms and gravity
Day of surgery cancellation rate after preoperative telephone nurse screening or comprehensive optimization visit
A phase-locked laser system based on double direct modulation technique for atom interferometry
Integrated Mach–Zehnder interferometer for Bose–Einstein condensates
Particle-wave duality enables the construction of interferometers for matter
waves, which complement optical interferometers in precision measurement
devices. This requires the development of atom-optics analogs to beam
splitters, phase shifters, and recombiners. Integrating these elements into a
single device has been a long-standing goal. Here we demonstrate a full
Mach-Zehnder sequence with trapped Bose-Einstein condensates (BECs) confined on
an atom chip. Particle interactions in our BEC matter waves lead to a
non-linearity, absent in photon optics. We exploit it to generate a
non-classical state having reduced number fluctuations inside the
interferometer. Making use of spatially separated wave packets, a controlled
phase shift is applied and read out by a non-adiabatic matter-wave recombiner.
We demonstrate coherence times a factor of three beyond what is expected for
coherent states, highlighting the potential of entanglement as a resource for
metrology. Our results pave the way for integrated quantum-enhanced matter-wave
sensors.Comment: 14 pages, 7 figures (including appendix); Nature Communications 4,
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