1 research outputs found
Clinical significance of mild inferolateral wall ischemia of the left ventricle on 99mTc-MIBI myocardial perfusion single photon emission computed tomography (SPECT)
INTRODUCTION: Mild ischemia
in the inferolateral wall on myocardial perfusion
imaging is seen frequently in practice. The aim
of this study is to assess the importance of the
above issue on myocardial perfusion SPECT
with coronary angiography.
PATIENTS AND METHODS: All patients enrolled
in this study exhibited mild ischemia of
the inferolateral wall on myocardial single photon
emission computed tomography (SPECT)
with 99mTc-MIBI, using the 20 left ventricular
segments model. Each patient completed a
questionnaire, including type of chest pain, risk
factors, and previous examinations, and all cases
were followed up for one year. Luminal stenosis
of >50% was classified as significant stenosis
on coronary angiography. A p value < 0.05
was considered statistically significant.
RESULTS: During investigation, 105 cases had
mild ischemia on myocardial perfusion imaging
(MPI) of which 36 subjects (22 male and 14 female)
underwent coronary angiography. The
mean age was 56.62±10.23 years old (age range:
36-73 years). The inferolateral wall was compared
to the left circumflex (LCX) territory. Nineteen
out of 36 (52.7%) cases had stenosis in the
LCX. Twenty-three of 105 (21.90%) underwent
revascularization during the one year follow up.
In multiple logistic regressions, with LCX stenosis
on angiography as the dependent variable,
only abnormal MPI was independently associated
significantly.
CONCLUSIONS: The findings of the study may
indicate that even a mild perfusion defect in the
inferolateral wall should be carefully managed,
especially in high-risk subjects for coronary
artery disease.
European Review for Medical and Pharmacological Sciences
Clinical significance of mild inferolateral wall
ischemia of the left ventricle on 99mTc-MIBI
myocardial perfusion single photon emission
computed tomography (SPECT)
M. ASSADI, A. ABDI-ARDEKANI1, M. POURBEHI2, A. AMINI2,
H. JAVADI3, I. NABIPOUR, M. ABBASZADEH3, M. ASSADI3
The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical Sciences,
Bushehr, Iran
1Department of Cardiology, Bushehr Heart Center, Faculty of Medicine, Bushehr University of
Medical Sciences, Bushehr, Iran
2Golestan Research Center of Gastroenterology and Hepatology (GRCGH), Golestan University of
Medical Sciences (GUOMS), Gorgan, Iran
3The Persian Gulf Nuclear Medicine Research Center, Bushehr University of Medical Sciences