THE EFFECTS OF CORE STABILITY TRAINING ON THE FUNCTIONAL MOVEMENT SCREEN AND POSTURAL STABILITY IN COLLEGIATE STUDENTS

This study evaluated effects of core stability training (CST) on the functional movement screen (FMS) and postural stability (PS) in healthy young collegiate students. 28 healthy collegiate female students were assigned to an experimental (CST exercises twice a week for six weeks) or control group (equal time of warm-up and stretching exercises only). The CST combined Pilates and Swiss ball exercise for fifty minutes, twice per week, for six weeks. FMS scores were evaluated by a certified professional. The PS was evaluated by the 8-direction limits of stability (LOS) test using the Biodex Balance System. Repeated measures analyses of variance (ANOVAs) revealed the FMS and LOS performances in the experiment group were significantly improved after training. It was concluded that regular CST can improve the performance of FMS and dynamic postural stability in healthy young students

THE EFFECTS OF UNSTABLE EXERCISE TRAINING ON DYNAMIC BALANCE AND ABDOMINAL MUSCLE STRENGTH IN YOUNG FEMALE INDIVIDUALS

The purpose of this study was to evaluate the effects of unstable exercise training (UET) on dynamic balance (DB) and abdominal muscle strength in young female individuals. 22 healthy collegiate female students underwent a series of UET sessions. DB was evaluated by the 8-direction limits of stability (LOS) test. Abdominal strength was measured using 60s sit-up test. The UET combined the Both Sides Utilized (BOSU) and Swiss ball exercises, undertaken for 90mins, twice per week, for 6 weeks. The LOS performance in overall, forward, right, forward-left, backward-right, and backward-left at level 6 also significantly improved post-training. Further, significant improvements were observed in the 60s sit-up test. It is concluded that regular UET can improve DB and abdominal muscle strength in young female individuals

THE EFFECTS OF CORE STABILITY TRAINING ON DYNAMIC BALANCE IN HEALTHY YOUNG STUDENTS

The purpose of this study was to evaluate the effects of core stability training (CST) on dynamic balance in healthy young students. 24 healthy collegiate female students volunteered and underwent a series of CST exercise. Dynamic balance was evaluated by the 8-direction limits of stability (LOS) test. The CST combined the Pilates mat and Swiss ball exercise, ninety minutes, twice per week, for six weeks. The LOS performance in right and backward-right directions at level 3 was significant improved in post-training than pre-training. Furthermore, The LOS performance in overall, forward, right, forward,left, backward-right, and backward-left directions at level 6 were significant improved in post-training than pre-training. It is concluded that regular CST can improve the dynamic postural stability in healthy young students

THE EFFECTS OF NEUROMUSCULAR TRAINING ON COUNTER-MOVEMENT JUMP PERFORMANCE IN HEALTHY YOUNG STUDENTS

Neuromuscular training (NT) programs are effective for improving measures of performance and used by athletes in all types of sports to increase sports performance. The purpose of this study was to evaluate the effects of NT on arm counter-movement jump (CMJ) performance in healthy young students. Thirteen healthy collegiate female students volunteered and underwent a series of NT exercise. The NT was performed for 50 minutes three times per week, for six weeks. Paired t-tests were used to analyze the differences in each parameter before and after training. The arm CMJ in explosive power, flight time, and jump height was statistically improved in post-training compared to pretraining. It is concluded that six weeks NT can improve the arm CMJ performance in young female students

THE RELATIONSHIPS BETWEEN THE FUNCTIONAL MOVEMENT SCREEN AND THE POSTURAL STABILITY IN COLLEGIATE ATHLETES

The Functional Movement Screen (FMS) is a tool developed recently not only to aid in the prevention of injury by objectively measuring dysfunction and asymmetries within movement patterns, but also could be used as a baseline for further strength, conditioning, or athletic development. The purpose of this study was to examine the relationships between the scores of FMS in relation to the postural stability (PS) in collegiate athletes. A total of 30 male, basketball athletes volunteered to join this study. The PS were measured by the Biodex Balance System as the displacements of the center of foot pressure (COP) in the limits of stability. The score of FMS were evaluated by one certified professional experts. The results showed that the score of FMS has relation to the performance of the PS in a certain extent, especially in the FMS-shoulder mobility to the LOS overall level 6 (r=.26-.41), in the FMS-active straight leg raise to the LOS forward, backward, right, right-back level 6 (r=.30-.39), and in the FMS-trunk stability push-up to the LOS right, back, and right-forward. It was concluded that the score of FMS might be used to evaluate and/or predict the performance of the PS in young, collegiate athletes

BETTER POSTURAL CONTROL DURING ACCURATE SHOOTING IN ELITE FEMALE BASKETBALL PLAYERS

The purpose of this study was to evaluate the differences of postural control (PC) during accurate and inaccurate shooting in elite female basketball players. 21 female professional basketball players recruited as subjects. The PC was evaluated by the Accusway as sway radius, velocity, radial and 95% area of the center of pressure (COP) during standard penalty line shooting. The results showed that the COP sway area during accurate shooting was significantly smaller than during inaccurate shooting (74.0 ± 37.9 vs. 110.6 ± 49.1, p < .05). Moreover, no significant differences were found between situations in the COP radius and velocity. This study found that during the accurate shooting, elite female basketball player had better PC which demonstrated that significant smaller COP sway area than inaccurate shooting

Gene Expression of Human Lung Cancer Cell Line CL1-5 in Response to a Direct Current Electric Field

Background: Electrotaxis is the movement of adherent living cells in response to a direct current (dc) electric field (EF) of physiological strength. Highly metastatic human lung cancer cells, CL1-5, exhibit directional migration and orientation under dcEFs. To understand the transcriptional response of CL1-5 cells to a dcEF, microarray analysis was performed in this study. Methodology/Principal Findings: A large electric-field chip (LEFC) was designed, fabricated, and used in this study. CL1-5 cells were treated with the EF strength of 0mV/mm (the control group) and 300mV/mm (the EF-treated group) for two hours. Signaling pathways involving the genes that expressed differently between the two groups were revealed. It was shown that the EF-regulated genes highly correlated to adherens junction, telomerase RNA component gene regulation, and tight junction. Some up-regulated genes such as ACVR1B and CTTN, and some down-regulated genes such as PTEN, are known to be positively and negatively correlated to cell migration, respectively. The protein-protein interactions of adherens junction-associated EF-regulated genes suggested that platelet-derived growth factor (PDGF) receptors and ephrin receptors may participate in sensing extracellular electrical stimuli. We further observed a high percentage of significantly regulated genes which encode cell membrane proteins, suggesting that dcEF may directly influence the activity of cell membrane proteins in signal transduction. Conclusions/Significance: In this study, some of the EF-regulated genes have been reported to be essential whereas others are novel for electrotaxis. Our result confirms that the regulation of gene expression is involved in the mechanism of electrotactic response

Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation

Many biochemical pathways involved in hair and skin development have not been investigated. Here, we reported on the lesions and investigated the mechanism underlying hair and skin abnormalities in Zdhhc13skc4 mice with a deficiency in DHHC13, a palmitoyl-acyl transferase encoded by Zdhhc13. Homozygous affected mice showed ragged and dilapidated cuticle of the hair shaft (CUH, a hair anchoring structure), poor hair anchoring ability, and premature hair loss at early telogen phase of the hair cycle, resulting in cyclic alopecia. Furthermore, the homozygous affected mice exhibited hyperproliferation of the epidermis, disturbed cornification, fragile cornified envelope (CE, a skin barrier structure), and impaired skin barrier function. Biochemical investigations revealed that cornifelin, which contains five palmitoylation sites at cysteine residues (C58, C59, C60, C95, and C101), was a specific substrate of DHHC13 and that it was absent in the CUH and CE structures of the affected mice. Furthermore, cornifelin levels were markedly reduced when two palmitoylated cysteines were replaced with serine (C95S and C101S). Taken together, our results suggest that DHHC13 is important for hair anchoring and skin barrier function and that cornifelin deficiency contributes to cyclic alopecia and skin abnormalities in Zdhhc13skc4 mice

The Origin of the White Roman Goose

In order to avoid interference from nuclear copies of mitochondrial DNA (numts), mtDNA of the white Roman goose (domestic goose) was extracted from liver mitochondria. The mtDNA control region was amplified using a long PCR strategy and then sequenced. Neighbor-joining, maximum parsimony, and maximum-likelihood approaches were implemented using the 1,177 bp mtDNA control region sequences to compute the phylogenetic relationships of the domestic goose with other geese. The resulting identity values for the white Roman geese were 99.1% (1,166/1,177) with western graylag geese and 98.8% (1,163/1,177) with eastern graylag geese. In molecular phylogenetic trees, the white Roman goose was grouped in the graylag lineage, indicating that the white Roman goose came from the graylag goose (Anser anser). Thus, the scientific name of the white Roman goose should be Anser anser 'White Roman.'

keynote 412 phase iii study of pembrolizumab plus chemoradiation vs chemoradiation alone for locally advanced head and neck squamous cell carcinoma hnscc

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