33 research outputs found
Minimal Informationally Complete Measurements for Pure States
We consider measurements, described by a positive-operator-valued measure
(POVM), whose outcome probabilities determine an arbitrary pure state of a
D-dimensional quantum system. We call such a measurement a pure-state
informationally complete (PSI-complete) POVM. We show that a measurement with
2D-1 outcomes cannot be PSI-complete, and then we construct a POVM with 2D
outcomes that suffices, thus showing that a minimal PSI-complete POVM has 2D
outcomes. We also consider PSI-complete POVMs that have only rank-one POVM
elements and construct an example with 3D-2 outcomes, which is a generalization
of the tetrahedral measurement for a qubit. The question of the minimal number
of elements in a rank-one PSI-complete POVM is left open.Comment: 2 figures, submitted for the Asher Peres festschrif
Leishmania amazonensis downregulates macrophage iNOS expression via Histone Deacetylase 1 (HDAC1): a novel parasite evasion mechanism.
The induced expression of nitric oxide synthase (iNOS) controls the intracellular growth of Leishmania in infected macrophages. Histones deacetylases (HDACs) negatively regulate gene expression through the formation of complexes containing transcription factors such as NF-κB p50/50. Herein, we demonstrated the occupancy of p50/p50_HDAC1 to iNOS promoter associated with reduced levels of H3K9Ac. Remarkably, we found increased levels of HDAC1 in L. amazonensis-infected macrophages. HDAC1 upregulation was not found in L. major-infected macrophages. The parasite intracellular load was reduced in HDAC1 knocked-down macrophages, which presented increased nitric oxide levels. HDAC1 silencing led to the occupancy of CBP/p300 to iNOS promoter and the rise of H3K9Ac modification. Importantly, the immunostaining of skin samples from hiporeactive cutaneous leishmaniasis patients infected with L. amazonensis, revealed high levels of HDAC1. In brief, L. amazonensis induces HDAC1 in infected macrophages, which contribute to parasite survival and is associated to hiporeactive stage found in L. amazonensis infected patients
Entanglement generation and transfer between remote atomic qubits interacting with squeezed field
A pair of two level atoms A1A2, prepared either in a separable state or in an
entangled state, interacts with a single mode of two mode squeezed cavity field
while a third atomic qubit B interacts with the second mode of the squeezed
field in a remote cavity. We analyze, numerically, the generation, sudden death
and revival of three qubit entanglement as a function of initial entanglement
of qubits A1A2 and degree of squeezing of electromagnetic field. Global
negativity of partially transposed state operator is used to quantify the
entanglement of three atom state. It is found that the initial entanglement of
two mode field as well as that of the pair A1A2, both, contribute to three atom
entanglement. A maximally entangled single excitation Bell pair in first cavity
and two mode field with squeeze parameter s=0.64 are the initial conditions
that optimize the peak value of three qubit mixed state entanglement. A smaller
value of s=0.4 under similar conditions is found to generate a three qubit
mixed state with comparable entanglement dynamics free from entanglement sudden
death.Comment: 14 pages, 7 figures, sections III and IV merged with section II and
analytic expressions moved to Appendices A and B. Figures improved and
corrected typo
Reperfusion hemorrhage following acute myocardial infarction: Assessment with T2*mapping and effect on measuring the area at risk
10.1148/radiol.2503081154Radiology2503916-92