3 research outputs found
A 2,3-butanedione protected chiral glycine equivalent - A new building block for the stereoselective synthesis of enantiopure N-protected α-amino acids
A new chiral glycine equivalent 7 has been synthesised from glycidol using a chiral memory protocol, and its use in the synthesis of N-Z protected alpha-amino acids was demonstrated in a series of diasteroselective lithium enolate alkylation reactions and subsequent acid hydrolyses