Isokinetic profile of Knee flexors and extensors in a jumpers population

Introduction. - This study explored concentric and eccentric profile of knee musculature in a jumpers population. Relationships between isokinetic assessment and field tests performances have also been explored. Materials. - Jumpers population presented higher knee flexors performances in concentric and eccentric mode and superior knee extensors strength in eccentric. Significant correlations between isokinetics and field tests results were exclusively observed with athletes quadriceps performances. A very high correlation (r = 0.93) was found between the second bound relative performance of the ten multijumps test and eccentric quadriceps relative peak torque. Conclusion. - Jumpers training may favour a specific muscular development. The knee extensors eccentric strength may be a major factor in the athletic performance. (c) 2005 Elsevier SAS. Tous droits reserves

Different response to amine fluoride by Streptococcus mutans and polymicrobial biofilms in a novel high-throughput active attachment model

Background/Aims: The antimicrobial resistance of microorganismsin biofilms and the polymicrobial interactions inthese biofilms that modulate resistance require novel strategies to evaluate the efficacy of caries-preventive compounds.The current study aimed to evaluate the effects of acaries-preventive agent in Streptococcus mutans and polymicrobial biofilms. Methods: We developed a novel highthroughput active attachment model. The model consisted of a custom-designed lid containing glass discs that fit on top of standard 24-well plates. Biofilms were formed using either S. mutans C180-2 or saliva. At the end of biofilm formation (up to 96 h) the biofilms were treated with amine fluoride (AmF) solutions. The viability of the biofilms was determined by CFU counts, and metabolic activity was measured via lactate production. Results: The effect of AmF on the viability of the polymicrobial biofilms was significantly less than that on the S. mutans biofilms, indicating a higher resistance in the complex biofilms. Both types of biofilms became more resistant to AmF with age. The higher resistan of the polymicrobial biofilms was not reflected in metabolic activity; in dose-response experiments AmF reduced lactate production in both types of biofilms to the same extent. Moreover, the age-induced increased resistance in the polymicrobial biofilms was less pronounced in terms of the inhibition of metabolic activity. Conclusions: This study clearly shows that when evaluating the efficacy of caries-preventive compounds it is essential to use appropriate polymicrobial biofilm models, and more importantly that efficacy needs to be judged based on the eduction of acid formation (i.e. cariogenic potential) as well as on bacterial viability

Intérêt de la stimulation du tibial antérieur et du long péronier latéral dans la marche de l'hémiplégique

peer reviewe

Etude dynamographique de la marche de l'hémiplégique: effets de différentes modalités d'électrostimulation

peer reviewe

Novel metabolic activity indicator in Streptococcus mutans biofilms

Antimicrobial resistance of micro-organisms in biofilms requires novel strategies to evaluate the efficacy of caries preventive agents in actual biofilms. Hence we investigated fluorescence intensity (FI) in Streptococcus mutans biofilms constitutively expressing green fluorescent protein (GFP). Upon addition of glucose FI in these biofilms increased significantly to steady state levels. FI-increase could be inhibited by oral care products in a dose-responsive manner. Lactic acid produced in these biofilms was measured at the end of the FI-recording. A linear correlation with a coefficient of 0.96 (p < 0.01) was observed between FI-increase and lactate production, irrespective of the inhibitor used. The viability of biofilm cells after chlorhexidine (CHX) titration was also examined. Reduction of FI-increase was observed at low concentrations of CHX whereas a loss in viability was only seen at high concentrations. In conclusion, GFP synthesis can be used as a metabolic activity indicator in S. mutans biofilms