12 research outputs found

    Linkage in mice of genes controlling an immunoglobulin kappa-chain marker and the surface alloantigen Ly-3 on T lymphocytes

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    Evidence obtained using recombinant inbred and congenic mouse strains has shown that the PC8 locus responsible for determining a marker on a single k chain in inbred mice is linked to the Ly - 2,3 locus on chromosome 6. The upper limit of the map distance between these loci is approximately three centimorgans. This finding is discussed in relation to other known light-chain variants that are associated with the Ly - 2,3 locus.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46753/1/251_2005_Article_BF01563929.pd
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