96 research outputs found

    Radio Jet-ISM Feedback on Sub-Galactic Scales

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    Energetic feedback by active galactic nuclei (AGNs) plays an important evolutionary role in the regulation of star formation (SF) on galactic scales. However, the effects of this feedback as a function of redshift and galaxy properties such as mass, environment, and cold gas content remain poorly understood. Given its unique combination of frequency range, angular resolution, and sensitivity, the ngVLA will serve as a transformational new tool in our understanding of how radio jets affect their surroundings. By combining broadband continuum data with measurements of the cold gas content and kinematics, the ngVLA will quantify the energetic impact of radio jets hosted by gas-rich galaxies as the jets interact with the star-forming gas reservoirs of their hosts

    Detection of paralytic shellfish toxins in mussels and oysters using the qualitative neogen lateral-flow immunoassay: an interlaboratory study

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    Paralytic shellfish toxins (PSTs) in bivalve molluscs represent a public health risk and are controlled via compliance with a regulatory limit of 0.8 mg saxitoxin (STX)center dot 2HCl equivalents per kilogram of shellfish meat (eq/kg). Shellfish industries would benefit from the use of rapid immunological screening tests for PSTs to be used for regulation, but to date none have been fully validated. An interlaboratory study involving 16 laboratories was performed to determine the suitability of the Neogen test to detect PSTs in mussels and oysters. Participants performed the standard protocol recommended by the manufacturer and a modified protocol with a conversion step to improve detection of gonyautoxin 1&4. The statistical analysis showed that the protocols had good homogeneity across all laboratories, with satisfactory repeatability, laboratory, and reproducibility variation near the regulatory level. The mean probability of detection (POD) at 0.8 mg STX center dot 2HCl eq/kg using the standard protocol in mussels and oysters was 0.966 and 0.997, respectively, and 0.968 and 0.966 using the modified protocol. The estimated LOD in mussels was 0.316 mg STX center dot 2HCl eq/kg with the standard and 0.682 mg STX center dot 2HCl eq/kg with the modified protocol, and 0.710 and 0.734 mg STX center dot 2HCl eq/kg for oysters, respectively. The Neogen test may be acceptable for regulatory purposes for oysters in accordance with European Commission directives in which the standard protocol provides, at the regulatory level, a probability of a negative response of 0.033 on 95% of occasions. Its use for mussels is less consistent at the regulatory level due to the wide prediction interval around the POD

    Local Toxicities of Chemotherapy

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