Radiation therapy in primary non-Hodgkin's lymphomas of the CNS

Twelve patients with primary non-Hodgkin's lymphomas of the CNS are described. Out of 5 CSF cytologies performed, 4 were positive. Radiotherapy was given to the tumour area in 3 patients, or to the whole brain in 5 patients. Four cases received radiotherapy to the spinal cord as well. Patients receiving whole CNS irradiation, including the spinal cord, seem to have a longer survival than patients with brain irradiation only. Out of the 5 patients with total brain irradiation, 2 showed a relapse in the spinal cord. It is suggested that therapy should be given not only to the tumour bearing areas, but should comprise the entire CNS

Non-Hodgkin's Lymphoma. Immunohistochemical and electron microscopical findings in relation to lightmicroscopy A study of 74 cases

From 74 patients with non-Hodgkin's lymphoma (NHL), fresh biopsy material from involved tissue was investigated histochemically and by light and electron microscopy. The results were compared with the light microscopical conclusions based on three currently utilized classifications, namely of Rappaport, Lukes, and Lennert. The separate groups of low-grade NHL appeared to consist of homogeneous cell populations, both in immunohistological as well as in enzymehistochemical and electron microscopical sense. On the contrary, high-grade NHL constituted a heterogeneous group in which supplementary (immunohistochemical, enzymehistochemical, and electron microscopical) investigation is very useful. All NHLs reacted with anti-human lymphocyte serum, including the so-called histiocytic NHLs according to the Rappaport classification, which proves their lymphocytic origin. Consequently the prefix histiocytic should be altered in a morphogenetically correct way. Without exception the B-cell NHLs were characterized by the presence of monoclonal immunoglobulin on the cell membrane and/or intracytoplasmically. In a part of the immunologically non-T-/non-B-/(null cell) NHLs, a B-cell origin was indicated by the presence of ATPase and/or 5 nucleotidase and a T-cell origin by the presence of dot-like acid phosphatase

Evaluation of adjuvant therapy in soft tissue sarcoma. A collaborative multidisciplinary approach

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women

Development and application of statistical models for medical scientific researc