56 research outputs found
On Deformations of n-Lie algebras
The aim of this paper is to review the deformation theory of -Lie
algebras. We summarize the 1-parameter formal deformation theory and provide a
generalized approach using any unital commutative associative algebra as a
deformation base. Moreover, we discuss degenerations and quantization of
-Lie algebras.Comment: Proceeding of the conference Dakar's Workshop in honor of Pr Amin
Kaidi. arXiv admin note: text overlap with arXiv:hep-th/9602016 by other
author
Hamiltonian dynamics and Noether symmetries in Extended Gravity Cosmology
We discuss the Hamiltonian dynamics for cosmologies coming from Extended
Theories of Gravity. In particular, minisuperspace models are taken into
account searching for Noether symmetries. The existence of conserved quantities
gives selection rule to recover classical behaviors in cosmic evolution
according to the so called Hartle criterion, that allows to select correlated
regions in the configuration space of dynamical variables. We show that such a
statement works for general classes of Extended Theories of Gravity and is
conformally preserved. Furthermore, the presence of Noether symmetries allows a
straightforward classification of singularities that represent the points where
the symmetry is broken. Examples of nonminimally coupled and higher-order
models are discussed.Comment: 20 pages, Review paper to appear in EPJ
Cosmological evolution and statefinder diagnostic for new holographic dark energy model in non flat universe
In this paper, the holographic dark energy model with new infrared cut-off
proposed by Granda and Oliveros has been investigated in spatially non flat
universe. The dependency of the evolution of equation of state, deceleration
parameter and cosmological evolution of Hubble parameter on the parameters of
new HDE model are calculated. Also, the statefinder parameters and in
this model are derived and the evolutionary trajectories in plane are
plotted. We show that the evolutionary trajectories are dependent on the model
parameters of new HDE model. Eventually, in the light of SNe+BAO+OHD+CMB
observational data, we plot the evolutionary trajectories in and
planes for best fit values of the parameters of new HDE model.Comment: 11 pages, 5 figures, Accepted by Astrophys. Space Sc
Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials
Stromal tumor-infiltrating lymphocytes (sTILs) are a potential predictive biomarker for immunotherapy response in metastatic triple-negative breast cancer (TNBC). To incorporate sTILs into clinical trials and diagnostics, reliable assessment is essential. In this review, we propose a new concept, namely the implementation of a risk-management framework that enables the use of sTILs as a stratification factor in clinical trials. We present the design of a biomarker risk-mitigation workflow that can be applied to any biomarker incorporation in clinical trials. We demonstrate the implementation of this concept using sTILs as an integral biomarker in a single-center phase II immunotherapy trial for metastatic TNBC (TONIC trial, NCT02499367), using this workflow to mitigate risks of suboptimal inclusion of sTILs in this specific trial. In this review, we demonstrate that a web-based scoring platform can mitigate potential risk factors when including sTILs in clinical trials, and we argue that this framework can be applied for any future biomarker-driven clinical trial setting
Cu-L X-RAY EMISSION SPECTRA FROM HIGH-Tc SUPERCONDUCTORS Y-Ba-CU-O BELOW AND ABOVE THE CRITICAL TEMPERATURE
The copper Lα and Lβ x-ray emission spectra from high-Tc Y-Ba-Cu-O superconductors, above and below the critical temperature, have been measured in a laboratory x-ray spectrograph. The Zn-Lα (1011 eV) photon energy was used to produce the Cu-2p1/2,3/2 primary vacancies (binding energies ~950 and 930 eVs, respectively). Changes in Cu-L x-ray emission spectra were observed indicating small changes in population of 3d and 4s electrons in the valence band when superconducting. For comparison Cu-L emission spectra £rom metallic Cu and
£rom polycrystalline Cu2O (valence I) and Cu0 (valence II) were recorded at room temperature
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