41 research outputs found
Cryptic torrent frogs of myanmar: An examination of the amolops marmoratus species complex with the resurrection of amolops afghanus and the identification of a new species
We investigated diversity in the Amolops marmoratus species complex within Myanmar using both molecular and morphological characters from recently collected specimens. Based on congruence between multivariate analyses of quantitative morphological characters and phylogenetic analyses of nucleotide variation in the 16S ribosomal gene conducted on 43 out of 182 frogs examined, we recognize A. marmoratus for specimens from the states of Mon and Shan and northern Tanintharyi Division and designate a neotype for this species; resurrect A. afghanus (Gnther, 1858) from synonymy with A. marmoratus for specimens from the northern state of Kachin and designate a lectotype for this species; recognize A. panhai for specimens from Tanintharyi, a new country record; and describe a new species for specimens from the western states of Chin and Rakhine, and Sagaing Division. © 2012 by the American Society of Ichthyologists and Herpetologists
The Role of Historical Narrative in Biblical Thought:the Tendencies Underlying Old Testament Historiography
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68403/2/10.1177_030908928100602102.pd
Setting-related influences on physical inactivity of older adults in residential care settings: a review
Studies on Melamine Formaldehyde (MF) Loaded Polyvinyl Acetate—Polyester Nonwoven Fabric Composites
Phosphoenolpyruvate carboxykinase in developing pea seeds is associated with tissues involved in solute transport and is nitrogen-responsive
Orientações recebidas do serviço de saúde por pacientes para o tratamento do portador de diabetes mellitus tipo 2
Evidence That Ternary Complex (eIF2-GTP-tRNA(i)(Met))–Deficient Preinitiation Complexes Are Core Constituents of Mammalian Stress Granules
Environmental stress-induced phosphorylation of eIF2α inhibits protein translation by reducing the availability of eIF2-GTP-tRNA(i)Met, the ternary complex that joins initiator tRNA(Met) to the 43S preinitiation complex. The resulting untranslated mRNA is dynamically routed to discrete cytoplasmic foci known as stress granules (SGs), a process requiring the related RNA-binding proteins TIA-1 and TIAR. SGs appear to be in equilibrium with polysomes, but the nature of this relationship is obscure. We now show that most components of the 48S preinitiation complex (i.e., small, but not large, ribosomal subunits, eIF3, eIF4E, eIF4G) are coordinately recruited to SGs in arsenite-stressed cells. In contrast, eIF2 is not a component of newly assembled SGs. Cells expressing a phosphomimetic mutant (S51D) of eIF2α assemble SGs of similar composition, confirming that the recruitment of these factors is a direct consequence of blocked translational initiation and not due to other effects of arsenite. Surprisingly, phospho-eIF2α is recruited to SGs that are disassembling in cells recovering from arsenite-induced stress. We discuss these results in the context of a translational checkpoint model wherein TIA and eIF2 are functional antagonists of translational initiation, and in which lack of ternary complex drives SG assembly