М. Ф. ФОН ДІТМАР – ЯСКРАВИЙПРЕДСТАВНИК ГІРНИЧОПРОМИСЛОВОЇ БУРЖУАЗІЇ ПІВДНЯ УКРАЇНИ(ОСТАННЯ ЧВЕРТЬ ХІХ– ПОЧАТОК ХХ СТ.)

В статті розглянуто постать відомого підприємця, науковця і суспільного діячаМ. Ф. фон Дітмара, визначено основні напрями його діяльності наПівдні Українив останній чверті ХІХ – на початку ХХ ст.The article considers the person of famous businessman, scientist and social activistM. F. von Ditmar, determines themain directions of his activity in SouthernUkraine in the last quarter ofXIX – the beginning ofXXcenturies

An apertureless near-field microscope for fluorescence imaging

We describe an apertureless near field microscope for imaging fluorescent samples. Optical contrast is generated by exploiting fluorescent quenching near a metallized atomic force microscope tip. This microscope has been used to image fluorescent latex beads with subdiffraction limit resolution. The use of fluorescence allows us to prove that the contrast mechanism is indeed spectroscopic in origin

African-American patients with cancer Talking About Clinical Trials (TACT) with oncologists during consultations: evaluating the efficacy of tailored health messages in a randomised controlled trial—the TACT study protocol

Introduction Low rates of accrual of African-American (AA) patients with cancer to therapeutic clinical trials (CTs) represent a serious and modifiable racial disparity in healthcare that impedes the development of promising cancer therapies. Suboptimal physician–patient consultation communication is a barrier to the accrual of patients with cancer of any race, but communication difficulties are compounded with AA patients. Providing tailored health messages (THM) to AA patients and their physician about CTs has the potential to improve communication, lower barriers to accrual and ameliorate health disparities. Objective (1) Demonstrate the efficacy of THM to increase patient activation as measured by direct observation. (2) Demonstrate the efficacy of THM to improve patient outcomes associated with barriers to AA participation. (3) Explore associations among preconsultation levels of: (A) trust in medical researchers, (B) knowledge and attitudes towards CTs, (C) patient-family member congruence in decision-making, and (D) involvement/information preferences, and group assignment. Methods and analysis First, using established methods, we will develop THM materials. Second, the efficacy of the intervention is determined in a 2 by 2 factorial randomised controlled trial to test the effectiveness of (1) providing 357 AA patients with cancer with THM with 2 different ‘depths’ of tailoring and (2) either providing feedback to oncologists about the patients\u27 trial THM or not. The primary analysis compares patient engaged communication in 4 groups preconsultation and postconsultation. Ethics and dissemination This study was approved by the Virginia Commonwealth University Institutional Review Board. To facilitate use of the THM intervention in diverse settings, we will convene ‘user groups’ at 3 major US cancer centres. To facilitate dissemination, we will post all materials and the implementation guide in publicly available locations

Tunneling Anisotropic Magnetoresistance in Co/AlOx/Au Tunnel Junctions

We observe spin-valve-like effects in nano-scaled thermally evaporated Co/AlOx/Au tunnel junctions. The tunneling magnetoresistance is anisotropic and depends on the relative orientation of the magnetization direction of the Co electrode with respect to the current direction. We attribute this effect to a two-step magnetization reversal and an anisotropic density of states resulting from spin-orbit interaction. The results of this study points to future applications of novel spintronics devices involving only one ferromagnetic layer.Comment: 11 pages, 5 figures. Accpted for publishing on Nano Letters, 200

Scanning apertureless fluorescence microscope

We describe a near-field apertureless fluorescence microscope, capable of imaging fluorescent latex beads with subwavelength precision. The instrument is based on a home- built tapping-mode atomic-force microscope, to which an inverted optical microscope was added. The fact that the wavelength of the fluorescence that we observe is different from the wavelength of the illumination allows for a relatively straightforward detection mechanism. Sample images are presented, along with evidence that the observe effect is of optical origin

A New Measurement of Cosmic Ray Composition at the Knee

The Dual Imaging Cerenkov Experiment (DICE) was designed and operated for making elemental composition measurements of cosmic rays near the knee of the spectrum at several PeV. Here we present the first results using this experiment from the measurement of the average location of the depth of shower maximum, , in the atmosphere as a function of particle energy. The value of near the instrument threshold of ~0.1 PeV is consistent with expectations from previous direct measurements. At higher energies there is little change in composition up to ~5 PeV. Above this energy is deeper than expected for a constant elemental composition implying the overall elemental composition is becoming lighter above the knee region. These results disagree with the idea that cosmic rays should become on average heavier above the knee. Instead they suggest a transition to a qualitatively different population of particles above 5 PeV.Comment: 7 pages, LaTeX, two eps figures, aas2pp4.sty and epsf.sty included, accepted by Ap.J. Let