Insulin resistance for glucose metabolism in disused soleus muscle of mice

Results of this study on mice provide the first direct evidence of insulin resistance for glucose metabolism in skeletal muscle that has undergone a previous period of reduced muscle usage. This lack of responsiveness to insulin developed in one day and in the presence of hypoinsulinemia. Future studies will utilize the model of hindlimb immobilization to determine the causes of these changes

Systematic study of Optical Feshbach Resonances in an ideal gas

Using a narrow intercombination line in alkaline earth atoms to mitigate large inelastic losses, we explore the Optical Feshbach Resonance (OFR) effect in an ultracold gas of bosonic $^{88}$Sr. A systematic measurement of three resonances allows precise determinations of the OFR strength and scaling law, in agreement with coupled-channels theory. Resonant enhancement of the complex scattering length leads to thermalization mediated by elastic and inelastic collisions in an otherwise ideal gas. OFR could be used to control atomic interactions with high spatial and temporal resolution.Comment: Significant changes to text and figure presentation to improve clarity. Extended supplementary material. 4 pages, 4 figures; includes supplementary material 8 pages, 4 figures. Submitted to Physical Review Letter

Sign problems, noise, and chiral symmetry breaking in a QCD-like theory

The Nambu-Jona-Lasinio model reduced to 2+1 dimensions has two different path integral formulations: at finite chemical potential one formulation has a severe sign problem similar to that found in QCD, while the other does not. At large N, where N is the number of flavors, one can compute the probability distributions of fermion correlators analytically in both formulations. In the former case one finds a broad distribution with small mean; in the latter one finds a heavy tailed positive distribution amenable to the cumulant expansion techniques developed in earlier work. We speculate on the implications of this model for QCD.Comment: 16 pages, 5 figures; Published version with minor changes from the origina

Amplitude dependent frequency, desynchronization, and stabilization in noisy metapopulation dynamics

The enigmatic stability of population oscillations within ecological systems is analyzed. The underlying mechanism is presented in the framework of two interacting species free to migrate between two spatial patches. It is shown that that the combined effects of migration and noise cannot account for the stabilization. The missing ingredient is the dependence of the oscillations' frequency upon their amplitude; with that, noise-induced differences between patches are amplified due to the frequency gradient. Migration among desynchronized regions then stabilizes a "soft" limit cycle in the vicinity of the homogenous manifold. A simple model of diffusively coupled oscillators allows the derivation of quantitative results, like the functional dependence of the desynchronization upon diffusion strength and frequency differences. The oscillations' amplitude is shown to be (almost) noise independent. The results are compared with a numerical integration of the marginally stable Lotka-Volterra equations. An unstable system is extinction-prone for small noise, but stabilizes at larger noise intensity

Is Frost Heaving Killing Your Legumes?

Frost heaving is a serious hazard to the maintenance of legume stands on many of our Iowa soils - especially on level claypan soils. But there are some things you can do to reduce your frost heaving losses