1,115 research outputs found

    Luttinger Parameter g for Metallic Carbon Nanotubes and Related Systems

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    The random phase approximation (RPA) theory is used to derive the Luttinger parameter g for metallic carbon nanotubes. The results are consistent with the Tomonaga-Luttinger models. All metallic carbon nanotubes, regardless if they are armchair tubes, zigzag tubes, or chiral tubes, should have the same Luttinger parameter g. However, a (10,10) carbon peapod should have a smaller g value than a (10,10) carbon nanotube. Changing the Fermi level by applying a gate voltage has only a second order effect on the g value. RPA theory is a valid approach to calculate plasmon energy in carbon nanotube systems, regardless if the ground state is a Luttinger liquid or Fermi liquid. (This paper was published in PRB 66, 193405 (2002). However, Eqs. (6), (9), and (19) were misprinted there.)Comment: 2 figure

    Antidote-Controlled Platelet Inhibition Targeting von Willebrand Factor with Aptamers

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    Thrombus formation is initiated by platelets and leads to cardiovascular, cerebrovascular, and peripheral vascular disease, the leading causes of morbidity and mortality in the Western world. A number of antiplatelet drugs have improved clinical outcomes for thrombosis patients. However, their expanded use, especially in surgery, is limited by hemorrhage. Here, we describe an antiplatelet agent that can have its activity controlled by a matched antidote. We demonstrate that an RNA aptamer targeting von Willebrand factor (VWF) can potently inhibit VWF-mediated platelet adhesion and aggregation. By targeting this important adhesion step, we show that the aptamer molecule can inhibit platelet aggregation in PFA-100 and ristocetin-induced platelet aggregation assays. Furthermore, we show that a rationally designed antidote molecule can reverse the effects of the aptamer molecule, restoring platelet function quickly and effectively over a clinically relevant period. This aptamer-antidote pair represents a reversible antiplatelet agent inhibiting a platelet specific pathway. Furthermore, it is an important step towards creating safer drugs in clinics through the utilization of an antidote molecule.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63204/1/oli.2007.0089.pd

    Low-temperature structural model of hcp solid C70_{70}

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    We report intermolecular potential-energy calculations for solid C_70{70} and determine the optimum static orientations of the molecules at low temperature; we find them to be consistent with the monoclinic structural model proposed by us in an earlier report [Solid State Commun. {\bf 105), 247 (1998)]. This model indicates that the C_5 axis of the molecule is tilted by an angle \approx18^o from the monoclinic b axis in contrast with the molecular orientation proposed by Verheijen {\it et al.} [J. Chem. Phys. {\bf 166}, 287 (1992)] where the C_5 axis is parallel to the monoclinic b axis. In this calculation we have incorporated the effective bond charge Coulomb potential together with the Lennard-Jones potential between the molecule at the origin of the monoclinic unit cell and its six nearest neighbours, three above and three below. The minimum energy configuration for the molecular orientations turns out to be at θ\theta=18^o, ϕ\phi=8^o, and ψ\psi=5^o, where θ\theta, ϕ\phi, and ψ\psi define the molecular orientations.Comment: ReVTeX (4 pages) + 2 PostScript figure

    First Measurement of the Branching Fraction of the Decay psi(2S) --> tau tau

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    The branching fraction of the psi(2S) decay into tau pair has been measured for the first time using the BES detector at the Beijing Electron-Positron Collider. The result is Bττ=(2.71±0.43±0.55)×103B_{\tau\tau}=(2.71\pm 0.43 \pm 0.55) \times 10^{-3}, where the first error is statistical and the second is systematic. This value, along with those for the branching fractions into e+e- and mu+mu of this resonance, satisfy well the relation predicted by the sequential lepton hypothesis. Combining all these values with the leptonic width of the resonance the total width of the psi(2S) is determined to be (252±37)(252 \pm 37) keV.Comment: 9 pages, 2 figure

    Methicillin sensitive Staphylococcus aureus producing Panton-Valentine leukocidin toxin in Trinidad & Tobago: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Certain <it>Staphylococcus aureus </it>strains produce Panton-Valentine leukocidin, a toxin that lyses white blood cells causing extensive tissue necrosis and chronic, recurrent or severe infection. This report documents a confirmed case of methicillin-sensitive <it>Staphylococcus aureus </it>strain harboring Panton-Valentine leukocidin genes from Trinidad and Tobago. To the best of our knowledge, this is the first time that such a case has been identified and reported from this country.</p> <p>Case presentation</p> <p>A 13-year-old Trinidadian boy of African descent presented with upper respiratory symptoms and gastroenteritis-like syptoms. About two weeks later he was re-admitted to our hospital complaining of pain and weakness affecting his left leg, where he had received an intramuscular injection of an anti-emetic drug. He deteriorated and developed septic arthritis, necrotizing fasciitis and septic shock with acute respiratory distress syndrome, leading to death within 48 hours of admission despite intensive care treatment. The infection was caused by <it>S. aureus</it>. Bacterial isolates from specimens recovered from our patient before and after his death were analyzed using microarray DNA analysis and <it>spa </it>typing, and the results revealed that the <it>S. aureus </it>isolates belonged to clonal complex 8, were methicillin-susceptible and positive for Panton-Valentine leukocidin. An autopsy revealed multi-organ failure and histological tissue stains of several organs were also performed and showed involvement of his lungs, liver, kidneys and thymus, which showed Hassal's corpuscles.</p> <p>Conclusion</p> <p>Rapid identification of Panton-Valentine leukocidin in methicillin-sensitive <it>S. aureus </it>isolates causing severe infections is necessary so as not to miss their potentially devastating consequences. Early feedback from the clinical laboratories is crucial.</p

    Methicillin sensitive Staphylococcus aureus producing Panton-Valentine leukocidin toxin in Trinidad & Tobago: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Certain <it>Staphylococcus aureus </it>strains produce Panton-Valentine leukocidin, a toxin that lyses white blood cells causing extensive tissue necrosis and chronic, recurrent or severe infection. This report documents a confirmed case of methicillin-sensitive <it>Staphylococcus aureus </it>strain harboring Panton-Valentine leukocidin genes from Trinidad and Tobago. To the best of our knowledge, this is the first time that such a case has been identified and reported from this country.</p> <p>Case presentation</p> <p>A 13-year-old Trinidadian boy of African descent presented with upper respiratory symptoms and gastroenteritis-like syptoms. About two weeks later he was re-admitted to our hospital complaining of pain and weakness affecting his left leg, where he had received an intramuscular injection of an anti-emetic drug. He deteriorated and developed septic arthritis, necrotizing fasciitis and septic shock with acute respiratory distress syndrome, leading to death within 48 hours of admission despite intensive care treatment. The infection was caused by <it>S. aureus</it>. Bacterial isolates from specimens recovered from our patient before and after his death were analyzed using microarray DNA analysis and <it>spa </it>typing, and the results revealed that the <it>S. aureus </it>isolates belonged to clonal complex 8, were methicillin-susceptible and positive for Panton-Valentine leukocidin. An autopsy revealed multi-organ failure and histological tissue stains of several organs were also performed and showed involvement of his lungs, liver, kidneys and thymus, which showed Hassal's corpuscles.</p> <p>Conclusion</p> <p>Rapid identification of Panton-Valentine leukocidin in methicillin-sensitive <it>S. aureus </it>isolates causing severe infections is necessary so as not to miss their potentially devastating consequences. Early feedback from the clinical laboratories is crucial.</p

    Measurement of the Inclusive Charm Cross Section at 4.03 GeV and 4.14 GeV

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    The cross section for charmed meson production at s=4.03\sqrt{s} = 4.03 and 4.14 GeV has been measured with the Beijing Spectrometer. The measurement was made using 22.3 pb1pb^{-1} of e+ee^+e^- data collected at 4.03 GeV and 1.5 pb1pb^{-1} of e+ee^+e^- data collected at 4.14 GeV. Inclusive observed cross sections for the production of charged and neutral D mesons and momentum spectra are presented. Observed cross sections were radiatively corrected to obtain tree level cross sections. Measurements of the total hadronic cross section are obtained from the charmed meson cross section and an extrapolation of results from below the charm threshold.Comment: 11 pages, 13 figures. The top level tex file is paper.tex. It builds the paper from other tex files in this .tar and the .eps file

    Measurements of the Cross Section for e+e- -> hadrons at Center-of-Mass Energies from 2 to 5 GeV

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    We report values of R=σ(e+ehadrons)/σ(e+eμ+μ)R = \sigma(e^+e^-\to {hadrons})/\sigma(e^+e^-\to\mu^+\mu^-) for 85 center-of-mass energies between 2 and 5 GeV measured with the upgraded Beijing Spectrometer at the Beijing Electron-Positron Collider.Comment: 5 pages, 3 figure

    Measurement of ψ(2S)\psi(2S) decays to baryon pairs

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    A sample of 3.95M ψ(2S)\psi(2S) decays registered in the BES detector are used to study final states containing pairs of octet and decuplet baryons. We report branching fractions for ψ(2S)ppˉ\psi(2S)\to p\bar{p}, ΛΛˉ\Lambda\bar{\Lambda}, Σ0Σˉ0\Sigma^0\bar{\Sigma}{}^0, ΞΞˉ+\Xi^-\bar{\Xi}{}^+, Δ++Δˉ\Delta^{++}\bar{\Delta}{}^{--}, Σ+(1385)Σˉ(1385)\Sigma^+(1385)\bar{\Sigma}{}^-(1385), Ξ0(1530)Ξˉ0(1530)\Xi^0(1530)\bar{\Xi}{}^0(1530), and ΩΩˉ+\Omega^-\bar{\Omega}{}^+. These results are compared to expectations based on the SU(3)-flavor symmetry, factorization, and perturbative QCD.Comment: 22 pages, 21 figures, 4 table

    Measurement of the Total Cross Section for Hadronic Production by e+e- Annihilation at Energies between 2.6-5 Gev

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    Using the upgraded Beijing Spectrometer (BESII), we have measured the total cross section for e+ee^+e^- annihilation into hadronic final states at center-of-mass energies of 2.6, 3.2, 3.4, 3.55, 4.6 and 5.0 GeV. Values of RR, σ(e+ehadrons)/σ(e+eμ+μ)\sigma(e^+e^-\to {hadrons})/\sigma(e^+e^-\to\mu^+\mu^-), are determined.Comment: Submitted to Phys. Rev. Let
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