119 research outputs found

    Scaling Properties of the Giant Dipole Resonance Width in Hot Rotating nuclei

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    We study the systematics of the giant dipole resonance width Γ\Gamma in hot rotating nuclei as a function of temperature TT, spin JJ and mass AA. We compare available experimental results with theoretical calculations that include thermal shape fluctuations in nuclei ranging from A=45 to A=208. Using the appropriate scaled variables, we find a simple phenomenological function Γ(A,T,J)\Gamma(A,T,J) which approximates the global behavior of the giant dipole resonance width in the liquid drop model. We reanalyze recent experimental and theoretical results for the resonance width in Sn isotopes and 208^{208}Pb.Comment: LaTeX, 4 pages with 4 figures (to appear in Phys. Rev. Lett.

    The study design of UDRIVE: the Naturalistic Driving Study across Europe for cars, trucks and scooters

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    Purpose: UDRIVE is the first large-scale European Naturalistic Driving Study on cars, trucks and powered two wheelers. The acronym stands for "European naturalistic Driving and Riding for Infrastructure & Vehicle safety and Environment". The purpose of the study is to gain a better understanding of what happens on the road in everyday traffic situations. Methods: The paper describes Naturalistic Driving Studies, a method which provides insight into the actual real-world behaviour of road users, unaffected by experimental conditions and related biases. Naturalistic driving can be defined as a study undertaken to provide insight into driver behaviour during everyday trips by recording details of the driver, the vehicle and the surroundings through unobtrusive data gathering equipment and without experimental control. Data collection will take place in six EU Member States. Results: Road User Behaviour will be studied with a focus on both safety and environment. The UDRIVE project follows the steps of the FESTA-V methodology, which was originally designed for Field Operational Tests. Conclusions: Defining research questions forms the basis of the study design and the specification of the recording equipment. Both will be described in this paper. Although the project has just started collecting data from drivers, we consider the process of designing the study as a major result which may help other initiatives to set up similar studies

    Theiler's Murine Encephalomyelitis Virus as a Vaccine Candidate for Immunotherapy

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    The induction of sterilizing T-cell responses to tumors is a major goal in the development of T-cell vaccines for treating cancer. Although specific components of anti-viral CD8+ immunity are well characterized, we still lack the ability to mimic viral CD8+ T-cell responses in therapeutic settings for treating cancers. Infection with the picornavirus Theiler's murine encephalomyelitis virus (TMEV) induces a strong sterilizing CD8+ T-cell response. In the absence of sterilizing immunity, the virus causes a persistent infection. We capitalized on the ability of TMEV to induce strong cellular immunity even under conditions of immune deficiency by modifying the virus to evaluate its potential as a T-cell vaccine. The introduction of defined CD8+ T-cell epitopes into the leader sequence of the TMEV genome generates an attenuated vaccine strain that can efficiently drive CD8+ T-cell responses to the targeted antigen. This virus activates T-cells in a manner that is capable of inducing targeted tissue damage and glucose dysregulation in an adoptive T-cell transfer model of diabetes mellitus. As a therapeutic vaccine for the treatment of established melanoma, epitope-modified TMEV can induce strong cytotoxic T-cell responses and promote infiltration of the T-cells into established tumors, ultimately leading to a delay in tumor growth and improved survival of vaccinated animals. We propose that epitope-modified TMEV is an excellent candidate for further development as a human T-cell vaccine for use in immunotherapy

    The Bank of Standardized Stimuli (BOSS), a New Set of 480 Normative Photos of Objects to Be Used as Visual Stimuli in Cognitive Research

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    There are currently stimuli with published norms available to study several psychological aspects of language and visual cognitions. Norms represent valuable information that can be used as experimental variables or systematically controlled to limit their potential influence on another experimental manipulation. The present work proposes 480 photo stimuli that have been normalized for name, category, familiarity, visual complexity, object agreement, viewpoint agreement, and manipulability. Stimuli are also available in grayscale, blurred, scrambled, and line-drawn version. This set of objects, the Bank Of Standardized Stimuli (BOSS), was created specifically to meet the needs of scientists in cognition, vision and psycholinguistics who work with photo stimuli

    OPTIMAX 2017 : radiation dose, image quality optimisation,the use of new technology in medical imaging

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    This year OPTIMAX settled in Oslo. After the successof previous years, we are proud to present the fourthEbook. As in previous years, the group was madeup of PhD-, MSc- and BSc students as well astutors from the seven European partner universities.Professional mix was drawn from medical physics/physics and radiography. OPTIMAX 2017 was partlyfunded by the partner universities and partly by theparticipants. Two students from South Africa and twofrom Brazil were invited by Hanze UAS (Groningen)and ESTeSL (Lisbon) summer school includedlectures and group projects in which experimentalresearch was conducted in four teams. Four research projects were performed with a focuson radiation dose optimization and image quality,namely: Possible dose reduction for pediatric patientsfor conventional radiology; Can the tube voltage belowered with the use of direct-conversion flat paneldetector system?; Impact of body size and kV in chestradiography; Quantity assessment on Image quality ofCBCT images of head phantom with implants of metaland ceramic objects.The last day of OPTIMAX 2017there was a poster session and a conference, in whichthe research teams presented their posters and oralpresentations. This book comprises of two sections, the first twochapters concern generic background informationabout international teamwork during the OPTIMAXsummerschool. The next chapters with theory on which the researchprojects were built. The second section containsthe research papers of the four research projects.Two research papers, Can the tube voltage belowered with the use of direct-conversion flat-paneldetector system? And Impact of body size and kV inchest radiography: Experimental receiver operatingcharacteristic analysis using a Multipurpose ChestPhantom “Lungman” have been accepted for the ECRconference, Vienna, 2018 as oral presentations

    Brazilian Consensus on Photoprotection

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