Heparin and heparin-induced thrombocytopenia

No Abstract

Vehicle, process, and hybrid theories of consciousness

Author's responseMartínez-Manrique contends that we overlook a possible nonconnectionist vehicle theory of consciousness. We argue that the position he develops is better understood as a hybrid vehicle/ process theory. We assess this theory and in doing so clarify the commitments of both vehicle and process theories of consciousness.Gerard O'Brien and Jonathan Opi

Intracortical inhibition assessed with paired-pulse transcranial magnetic stimulation is modulated during shortening and lengthening contractions in young and old adults

Abstract not availableGeorge M. Opie, John G. Semmle

Age-related differences in short- and long-interval intracortical inhibition in a human hand muscle

Abstract not availableGeorge M. Opie, John G. Semmle

“Sports Law”: Implications for the Development of International, Comparative, and National Law and Global Dispute Resolution

In this Article, we observe that legal regulation of national and international sports competition has become extremely complex and has entered a new era, which provides fertile ground for the creation and evolution of broader legal jurisprudence with potentially widespread influence and application. Our principal aim is to draw these developments to the attention of legal scholars and attorneys not necessarily familiar with sports law. Specifically, the evolving law of sports is having a significant influence on the development of international and national laws, is establishing a body of substantive legal doctrine ripe for analysis from a comparative law perspective, and has important implications for global dispute resolution. For example, the global processes used to establish an international sports antidoping code and to resolve a broad range of Olympic and international sports disputes (which is rapidly creating a body of global private law) provide paradigms of international cooperation and global lawmaking. In addition, judicial resolution of sports-related cases may develop jurisprudence with new applications and influence. Our objective is to generate greater awareness of the importance of sports, not only as a worldwide cultural phenomenon and a significant part of the twenty-first-century global economy, but as a rich source of international and national public and private laws that provide models for establishing, implementing, and enforcing global legal norms

Age-related differences in pre- and post-synaptic motor cortex inhibition are task dependent

Abstract not availableGeorge M. Opie, Michael C. Ridding, John G. Semmle

Warfarin in non-valvular atrial fibrillation

The development of novel oral anticoagulants that are effective alternatives to warfarin in non-valvular atrial fibrillation (AF) is a welcome advance. However, a variety of unresolved problems with their use, and not least with their cost, make it important to re-evaluate the use of warfarin as it will likely remain the anticoagulant of choice in South African patients with non-valvular AF for the foreseeable future. In this article, we review the correct clinical use of warfarin. Guidance is provided on commencing warfarin treatment, maintenance dosing, the recommended steps when temporary withdrawal of treatment is necessary, the management of bleeding, and the use of warfarin in chronic kidney disease. Techniques for changing from warfarin to one of the new oral anticoagulants and vice versa are included