Dark matter and non-Newtonian gravity from General Relativity coupled to a fluid of strings

An exact solution of Einstein's field equations for a point mass surrounded by a static, spherically symmetric fluid of strings is presented. The solution is singular at the origin. Near the string cloud limit there is a $1/r$ correction to Newton's force law. It is noted that at large distances and small accelerations, this law coincides with the phenomenological force law invented by Milgrom in order to explain the flat rotation curves of galaxies without introducing dark matter. When interpreted in the context of a cosmological model with a string fluid, the new solution naturally explains why the critical acceleration of Milgrom is of the same order of magnitude as the Hubble parameter.Comment: 12 pages, REVTeX, no figure

The Bright Side of Dark Matter

We show that it is not possible in the absence of dark matter to construct a four-dimensional metric that explains galactic observations. In particular, by working with an effective potential it is shown that a metric which is constructed to fit flat rotation curves in spiral galaxies leads to the wrong sign for the bending of light i.e. repulsion instead of attraction. Hence, without dark matter the motion of particles on galactic scales cannot be explained in terms of geodesic motion on a four- dimensional metric. This reveals a new bright side to dark matter: it is indispensable if we wish to retain the cherished equivalence principle.Comment: 7 pages, latex, no figures. Received an honorable mention in the 1999 Gravity research Foundation Essay Competition. Submitted to Phys. Rev. Let

Role for targeted resection in the multidisciplinary treatment of metastatic gastrointestinal stromal tumor

The management of advanced gastrointestinal stromal tumors (GISTs) has evolved in the modern era due to the discovery of c-kit mutations and the development of tyrosine kinase inhibitors (TKIs). Until the advent of TKIs such as imatinib, the median survival reported for patients with advanced GIST was 19 months. Although surgery is the treatment of choice for resectable primary GIST, its role in cases of recurrence and metastasis remains to be unclear. This review outlines the potential beneficial role of repeat surgical resection in the multidisciplinary treatment of advanced GIST in the era of TKIs

Modified gravity without dark matter

On an empirical level, the most successful alternative to dark matter in bound gravitational systems is the modified Newtonian dynamics, or MOND, proposed by Milgrom. Here I discuss the attempts to formulate MOND as a modification of General Relativity. I begin with a summary of the phenomenological successes of MOND and then discuss the various covariant theories that have been proposed as a basis for the idea. I show why these proposals have led inevitably to a multi-field theory. I describe in some detail TeVeS, the tensor-vector-scalar theory proposed by Bekenstein, and discuss its successes and shortcomings. This lecture is primarily pedagogical and directed to those with some, but not a deep, background in General RelativityComment: 28 pages, 10 figures, lecture given at Third Aegean Summer School, The Invisible Universe: Dark Matter and Dark Energy, minor errors corrected, references update

Cosmological extrapolation of MOND

Regime of MOND, which is used in astronomy to describe the gravitating systems of island type without the need to postulate the existence of a hypothetical dark matter, is generalized to the case of homogeneous distribution of usual matter by introducing a linear dependence of the critical acceleration on the size of region under consideration. We show that such the extrapolation of MOND in cosmology is consistent with both the observed dependence of brightness on the redshift for type Ia supernovae and the parameters of large-scale structure of Universe in the evolution, that is determined by the presence of a cosmological constant, the ordinary matter of baryons and electrons as well as the photon and neutrino radiation without any dark matter.Comment: 20 pages, 5 figures, comments adde