Neural Network based p-q-r Theory for Harmonic Reduction and Neutral Current Mitigation

The power quality compensator chosen in this paper is a DSTATCOM which integrates a three phase four leg Voltage Source Converter (VSC) with a DC capacitor. The major role of the DSTATCOM is to mitigate the components of harmonic/reactive current present in the line current thereby shapes the grid current to be sinusoidal and improves the power factor nearly unity under varying conditions. In addition DSATATCOM mitigates neutral current (Isn) and balances the load currents under unbalanced conditions in three phase four wire (3P4W) distribution system. The control strategy proposed for the DSTATCOM is a Neural Network (NN) based p-q-r theory with two Artificial Neural Network (ANN) controllers for a 3P4W distribution system. The reference signal for 3P3W Shunt Active Power Filter (SAPF) is calculated by implementing an ANN controller. The alleviation of Isn under unbalanced condition is achieved by another ANN controller which produces reference signal for the 1Φ APF. The performance of the proposed DSTATCOM is analysed for various conditions through simulations in MATLAB SIMULINK and the simulation results justify the effectiveness of the propounded NN based control algorithm for DSTATCOM

Improved power quality buck boost converter for SMPS

In this paper, a Neural Network (NN) controlled Buck-Boost Converter (BBC) based Switched Mode Power Supply (SMPS) for a PC application is proposed. The proposed BBC is analyzed, modeled and designed for the rated load. Generally, the utilization of Multiple Output SMPS (MOSMPS) for PC application introduces Power Quality (PQ) issues in the power system network. Unlike conventional SMPS the proposed NN controlled BBC can accomplish improvement of power quality. The NN controller reduces the Total Harmonic Distortion (THD) of source current below 5%, maintains input side Power Factor (PF) to be nearly unity and improves the output voltage regulation. In the proposed system, NN controller replaces the conventional PI controller and overcomes the drawbacks of the conventional system. The proposed BBC is validated adopting MATLAB/SIMULINK software. The simulation analysis validate that the proposed NN controlled BBC performs better than conventional converter in terms of PQ indices under fluctuating conditions

DRAFT GENOME SEQUENCE OF HUMAN HERPES VIRUS-4 VRF_EBV_01, AN EPSTEIN BARR VIRUS OBTAINED FROM A PEDIATRIC POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD) PATIENT

Objectives: To decode the sequence of Epstein-barr virus (EBV) genome isolated from a pediatric patient with post transplant lymphoproliferative disorder (PTLD).Methods: EBV culture harvested from the blood sample of a 4-year-old patient with post liver transplant lymphoproliferative disorder prior to treatment was subjected to whole genome sequencing using Illumina platform. Generated data were subjected to various quality analysis and the filtered sequences were submitted to NCBI and published under accession number KM269735-KM269744.Results: Annotation results of VRF_ EBV01 genome using Prokka tool and manual blast search infers 48 hypothetical proteins, each 3 genes coding for Epstein-Barr nuclear antigen 3A and 3B and each one gene coding for Epstein-Barr nuclear antigens 1, 4, 4B and DNA primase UL70 protein. Single copy of genes coding for each variant of Tegument protein BSRF1, BLRF2, BGLF2 mir-BART 1,2,3,5,7,12,15,17,20 and two copies of gene coding for primary envelopment factor BFRF1 gene was also found.Conclusion: To date, only eight EBV genome sequences have been reported worldwide and there is no genome sequence reported from India. This study is the first of its kind to report on EBV genome from a post–transplant lymphoproliferative disorder to the scientific community for the welfare of research against EBV diagnostic markers and drug discovery.Â

FIRST COMPLETE GENOME SEQUENCE OF OCULAR ISOLATE CARRYING BLAVIM-2 MEDIATED MULTI-DRUG-RESISTANT(MDR) PSEUDOMONAS AERUGINOSA VRFPA04 FROM INDIA AND TWO DRAFT GENOME SEQUENCE OF OCULAR ISOLATES PSEUDOMONAS AERUGINOSA VRFPA03 AND VRFPA05 HARBORING NOVEL BLA

Objective: Ocular infections caused by Multi-Drug resistant (MDR) Pseudomonas aeruginosa are rare but increasingly identified recently. In this context, we have applied Next Generation Sequencing (NGS) based whole genome analysis on three ocular isolates of MDR P. aeruginosa to explore the drug resistance determinants and genomic level variations.Methods: Three ocular isolates namely P. aeruginosa VRFP03, VRFPA04 from two different Keratitis patients (corneal button) and VRFPA05 isolated from the intraocular specimen (Vitreous humor) collected from an endophthalmitis patient was included in this study. Phenotypically VRFPA03, VRFPA04, VRFPA05 showed resistant to a wide group of antibiotics and hence they were taken up for Ion Torrent-PGM based whole genome study.Results: Here, we report the first complete genome sequence of MDR P. aeruginosa VRFPA04 isolated from the Indian keratitis patients clinical specimen (corneal button) submitted to L & T Microbiology Research Centre, Vision Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India. The circular chromosome of P aeruginosa VRFPA04 was published under the NCBI accession number CP008739.2. Two Draft genome sequences of MDR P. aeruginosa VRFPA03 and VRFPA05 were published under the NCBI accession number ATNK01000000.1 and AXZJ01000000.1 respectively.Conclusion: Preliminary genomic analysis on P. aeruginosa VRFPA03, VRFPA04 and VRFPA05 revealed the presence of Metallo Beta-lactamase (MBL) genes blaDim-1, blaVim-2 andblaGes-9 genes respectively. These MBL genes were concordance with a phenotypic pattern of carbapenem resistance among VRFPA03, VRFPA04 and VRFPA05 strains, respectively. We are proud to share that this is the first of its kind to report blaDIM-1 from an Indianisolate especially from an Ocular origin.Â

COMPARATIVE STUDY OF HAEMATOLOGICAL PARAMETERS IN FISHES FROM THE NATURAL HABITAT, MADURAI REGION

The heamatological profile of two freshwater fishes Labeo rohita (Rohu) and Channa striatus (Murrel) with a relationship to the sex and the water quality under natural habitat was analyzed. The freshwater fishes were collected from the pond located in Thodaneri, Vadipatti taluk, Madurai district, Tamil Nadu, India. In heamatology studies, no significant variation was observed in Heamoglobin content and found almost the same in both the fish irrespective of the sex and also falls in the range of control value. In differential Leucocyte count (DLC) the following blood components Lymphocyte, Eosinophil, and Monocyte count were significantly higher than the control values and the values are found maximum in Rohu when compared to Murrel.RBC (Erythrocyte) count was almost the same in both the fish and the value falls between the range of control value Packed Cell Volume (PCV) count was almost the same in both the fish and the value falls between the range of control value. The values of Hb and PCV were found higher in male fish as compared to female fish. The leucocyte count is also higher in the males when compared to the females of both Rohu and Murrel. These may be also influenced by physiological activity, feeding habits, infectious agents, water quality parameters, and the environmental stress on the organism

Complication of Salmonella Bacteremia in a Case of Treated Fungal Endophthalmitis

This is to report a case of bacteremia caused by Salmonella typhi in a treated unilateral fungal endogenous endophthalmitis in an 18-year-old male from one of the South Asian countries. Microbiological and molecular investigations were carried out on the eviscerated material and routine blood culture was carried out. Direct examination of eviscerated material revealed the presence of fungal filaments. However, Salmonella typhi was isolated from both specimens, which was confirmed by Polymerase chain reaction targeting the 16SrRNA gene, sequencing, and random amplification of polymorphic DNA showed that they belonged to the same clone. The presence of Salmonella bacteremia in a treated unilateral fungal endophthalmitis, among young adult patients is rare and systemic symptoms should be investigated

CSRR Loaded 2x1 Triangular MIMO Antenna for LTE Band Operation

A 2´1 (two-element) multiple-input multiple-output (MIMO) patch antenna system is designed and fabricated for (2.43 – 2.57) GHz LTE band 7 operation. It uses comple-mentary split -ring resonator (CSRR) loading on its ground plane for antenna miniaturization. This reduces the single-element antenna size by 76%. The total board size of the proposed MIMO antenna system, including the GND plane is 50´50´0.8mm3, while the single-patch antenna element has a size of 18.5 ´16mm2. The antenna is fabricated and tested. Measured results are in good agreement with simulations. A minimum measured isolation of 10 dB is obtained given the close interelement spacing of 0.17λ

CSRR Loaded 2x1 Triangular MIMO Antenna for LTE Band Operation

A 2´1 (two-element) multiple-input multiple-output (MIMO) patch antenna system is designed and fabricated for (2.43 – 2.57) GHz LTE band 7 operation. It uses comple-mentary split -ring resonator (CSRR) loading on its ground plane for antenna miniaturization. This reduces the single-element antenna size by 76%. The total board size of the proposed MIMO antenna system, including the GND plane is 50´50´0.8mm3, while the single-patch antenna element has a size of 18.5 ´16mm2. The antenna is fabricated and tested. Measured results are in good agreement with simulations. A minimum measured isolation of 10 dB is obtained given the close interelement spacing of 0.17λ

Attitude and perception versus reality of COVID-19 vaccination among healthcare professional: a survey

Background: The pandemic of COVID-19 infection has almost paralyzed the world since the first infection was reported in December 2019. We have seen 3 waves of infection in the country, out of which the second wave caused by the delta variant was the most severe. Along with the preventive measures of masking, maintaining social distance, and handwashing, the vaccines seemed to be the most logical next step. Many vaccines received emergency use approvals with hardly any efficacy and adverse effects data available with the process inducing a significant amount of anxiety among the public. This survey was aimed at understanding the attitude and perception of our hospital employees towards COVID-19 vaccination. Methods: This is a cross-sectional study conducted among health care workers (HCW) at CMC, Vellore between March 2021 to July 2021. The HCWs who are willing to participate in this study were recruited and collected the quantitative data on their attitude and perception towards COVID vaccine. In-depth interviews were conducted among those who did not take vaccine to understand the reasons for not taking vaccine. The data were analyzed using statistical package for the social sciences (SPSS). Results: The survey results were analyzed on 435 HCWs. 58.4 percent of the HCWs trust the institutional protocols as the trusted source of information about vaccine. Most of the HCWs agreed that vaccines are the only protective way, and they are safe and effective. Conclusions: Sensitization and awareness programs with transparency of vaccine development processes, safety and efficacy will help remove barriers