1,666 research outputs found
Traces of Thermalization from Transverse Momentum Fluctuations in Nuclear Collisions
Scattering of particles produced in Au+Au collisions at RHIC can wrestle the
system into a state near local thermal equilibrium. I illustrate how
measurements of the centrality dependence of the mean transverse momentum and
its fluctuations can exhibit this thermalization.Comment: 4 pages, 2 eps figures, final version to appear in PR
A Candidate Protoplanet in the Taurus Star Forming Region
HST/NICMOS images of the class I protostar TMR-1 (IRAS04361+2547) reveal a
faint companion with 10.0" = 1400 AU projected separation. The central
protostar is itself resolved as a close binary with 0.31" = 42 AU separation,
surrounded by circumstellar reflection nebulosity. A long narrow filament seems
to connect the protobinary to the faint companion TMR-1C, suggesting a physical
association. If the sources are physically related then we hypothesize that
TMR-1C has been ejected by the protobinary. If TMR-1C has the same age and
distance as the protobinary then current models indicate its flux is consistent
with a young giant planet of several Jovian masses.Comment: 16 pages, 1 figure, Accepted by Astrophysical Journal Letters,
Related information is available at http://www.extrasolar.co
Optical Observations of the Binary Pulsar System PSR B1718-19: Implications for Tidal Circularization
We report on Keck and Hubble Space Telescope optical observations of the
eclipsing binary pulsar system PSR B1718-19, in the direction of the globular
cluster NGC 6342. These reveal a faint star (; Vega
system) within the pulsar's 0\farcs5 radius positional error circle. This may
be the companion. If it is a main-sequence star in the cluster, it has radius
\rcomp\simeq0.3 \rsun, temperature \teff\simeq3600 K, and mass
\mcomp\simeq0.3 \msun. In many formation models, however, the pulsar (spun up
by accretion or newly formed) and its companion are initially in an eccentric
orbit. If so, for tidal circularization to have produced the present-day highly
circular orbit, a large stellar radius is required, i.e., the star must be
bloated. Using constraints on the radius and temperature from the Roche and
Hayashi limits, we infer from our observations that \rcomp\simlt0.44 \rsun
and \teff\simgt3300 K. Even for the largest radii, the required efficiency of
tidal dissipation is larger than expected for some prescriptions.Comment: 10 pages, 2 figures, aas4pp2.sty. Accepted for publication in Ap
The kidney, subclinical thyroid disease and cardiovascular outcomes in older patients
Objective:
Thyroid hormones have been implicated to play a role in cardiovascular disease, along with studies linking thyroid hormone to kidney function. The aim of this study is to investigate whether kidney function modifies the association of subclinical thyroid dysfunction and the risk of cardiovascular outcomes.
Methods:
In total, 5804 patients were included in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). For the current analysis, 426 were excluded because of overt thyroid disease at baseline or 6 months, 266 because of inconsistent thyroid function at baseline and 6 months, 294 because of medication use that could influence thyroid function, and 16 because of missing kidney or thyroid values. Participants with normal fT4 were classified, based on TSH both at inclusion and 6 months, into three groups: subclinical hypothyroidism (TSH >4.5 mIU/L); euthyroidism (TSH = 0.45–4.5 mIU/L); and subclinical hyperthyroidism (TSH <0.45 mIU/L). Strata of kidney function were made based on estimated glomerular filtration rate into three clinically relevant groups: <45, 45–60, and >60 mL/min/1.73 m2. The primary endpoint consists of death from coronary heart disease, non-fatal myocardial infarction and (non)fatal stroke.
Results:
Mean age was 75.3 years, and 49.0% patients were male. Mean follow-up was 3.2 years. Of all participants, 109 subjects (2.2%) had subclinical hypothyroidism, 4573 (94.0%) had euthyroidism, and 182 (3.7%) subclinical hyperthyroidism. For patients with subclinical hypothyroidism, euthyroidism, and subclinical hyperthyroidism, primary outcome occurred in 9 (8.3%), 712 (15.6%), and 23 (12.6%) patients, respectively. No statistically significant relationship was found between subclinical thyroid dysfunction and primary endpoint with adjusted hazard ratios of 0.51 (0.24–1.07) comparing subclinical hyperthyroidism and 0.90 (0.58–1.39) comparing subclinical hypothyroidism with euthyroidism. Neither was this relationship present in any of the strata of kidney function, nor did kidney function interact with subclinical thyroid dysfunction in the association with primary endpoint (P interaction = 0.602 for subclinical hyperthyroidism and 0.388 for subclinical hypothyroidism).
Conclusions:
In this secondary analysis from PROSPER, we found no evidence that the potential association between thyroid hormones and cardiovascular disease is modified by kidney function in older patients with subclinical thyroid dysfunction
An X-ray and Optical Investigation of the Starburst-driven Superwind in the Galaxy Merger Arp 299
We present a detailed investigation of the X-ray and optical properties of
the starburst-merger system Arp299 (NGC 3690, Mrk 171), with an emphasis on its
spectacular gaseous nebula. We analyse \rosat and \asca X-ray data and optical
spectra and narrow-band images. We suggest that the on-going galaxy collision
has tidally-redistributed the ISM of the merging galaxies. The optical
emission-line nebula results as this gas is photoionized by radiation that
escapes from the starburst, and is shock-heated, accelerated, and pressurized
by a `superwind' driven by the collective effect of the starburst supernovae
and stellar winds. The X-ray nebula in Arp 299 is is plausibly a mass-loaded
flow of adiabatically-cooling gas that carries out a substantial fraction of
the energy and metals injected by the starburst at close to the escape velocity
from Arp 299. The mass outflow rate likely exceeds the star-formation rate in
this system. We conclude that powerful starbursts are able to heat (and
possibly eject) a significant fraction of the ISM in merging galaxies.Comment: 54 pages, 17 postscript figures, AAS late
Search for positively charged strangelets and other related results with E864 at the AGS
We report on the latest results in the search for positively charged
strangelets from E864's 96/97 run at the AGS with sensitivity of about per central collision. This contribution also contains new results of
a search for highly charged strangelets with . Production of light
nuclei, such as and , is presented as well. Measurements of yields
of these rarely produced isotopes near midrapidity will help constrain the
production levels of strangelets via coalescence. E864 also measures antiproton
production which includes decays from antihyperons. Comparisons with antiproton
yields measured by E878 as a function of centrality indicate a large
antihyperon-to-antiproton ratio in central collisions.Comment: 8 pages, 4 figures; Talk at SQM'98, Padova, Italy (July 20-24th,
1998
Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial.
Importance: Iron deficiency is present in approximately 50% of patients with heart failure with reduced left ventricular ejection fraction (HFrEF) and is an independent predictor of reduced functional capacity and mortality. However, the efficacy of inexpensive readily available oral iron supplementation in heart failure is unknown.
Objective: To test whether therapy with oral iron improves peak exercise capacity in patients with HFrEF and iron deficiency.
Design, Setting, and Participants: Phase 2, double-blind, placebo-controlled randomized clinical trial of patients with HFrEF (
Interventions: Oral iron polysaccharide (n = 111) or placebo (n = 114), 150 mg twice daily for 16 weeks.
Main Outcomes and Measures: The primary end point was a change in peak oxygen uptake (V̇o2) from baseline to 16 weeks. Secondary end points were change in 6-minute walk distance, plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels, and health status as assessed by Kansas City Cardiomyopathy Questionnaire (KCCQ, range 0-100, higher scores reflect better quality of life).
Results: Among 225 randomized participants (median age, 63 years; 36% women) 203 completed the study. The median baseline peak V̇o2 was 1196 mL/min (interquartile range [IQR], 887-1448 mL/min) in the oral iron group and 1167 mL/min (IQR, 887-1449 mL/min) in the placebo group. The primary end point, change in peak V̇o2 at 16 weeks, did not significantly differ between the oral iron and placebo groups (+23 mL/min vs -2 mL/min; difference, 21 mL/min [95% CI, -34 to +76 mL/min]; P = .46). Similarly, at 16 weeks, there were no significant differences between treatment groups in changes in 6-minute walk distance (-13 m; 95% CI, -32 to 6 m), NT-proBNP levels (159; 95% CI, -280 to 599 pg/mL), or KCCQ score (1; 95% CI, -2.4 to 4.4), all P \u3e .05.
Conclusions and Relevance: Among participants with HFrEF with iron deficiency, high-dose oral iron did not improve exercise capacity over 16 weeks. These results do not support use of oral iron supplementation in patients with HFrEF.
Trial Registration: clinicaltrials.gov Identifier: NCT02188784
An Interstellar Conduction Front Within a Wolf-Rayet Ring Nebula Observed with the GHRS
With the High Resolution Spectrograph aboard the Hubble Space Telescope we
obtained high signal-to-noise (S/N > 200 - 600 per 17 km/s resolution element)
spectra of narrow absorption lines toward the Wolf-Rayet star HD 50896. The
ring nebula S308 that surrounds this star is thought to be caused by a
pressure-driven bubble bounded by circumstellar gas (most likely from a red
supergiant or luminous blue variable progenitor) pushed aside by a strong
stellar wind. Our observation has shown for the first time that blueshifted
(approximately 70 km/s relative to the star) absorption components of C IV and
N V arise in a conduction front between the hot interior of the bubble and the
cold shell of swept-up material. These lines set limits on models of the
conduction front. Nitrogen in the shell appears to be overabundant by a factor
~10. The P Cygni profiles of N V and C IV are variable, possibly due to a
suspected binary companion to HD 50896.Comment: 32 pages, Latex, to appear in the Astrophysical Journal, April, 199
- …