Longitudinal variations, the opposition effect and monochromatic albedos for Mars

Magnitude at zero phase, phase coefficient, and monochromatic albedo computed for Mars as function of wavelengt

Non-linear photonic crystals as a source of entangled photons

Non-linear photonic crystals can be used to provide phase-matching for frequency conversion in optically isotropic materials. The phase-matching mechanism proposed here is a combination of form birefringence and phase velocity dispersion in a periodic structure. Since the phase-matching relies on the geometry of the photonic crystal, it becomes possible to use highly non-linear materials. This is illustrated considering a one-dimensional periodic Al$_{0.4}$Ga$_{0.6}$As / air structure for the generation of 1.5 $\mu$m light. We show that phase-matching conditions used in schemes to create entangled photon pairs can be achieved in photonic crystals.Comment: 4 pages, 3 figure

Evidence that hematopoietic stem cell function is preserved during aging in long-lived S6K1 mutant mice

The mechanistic target of rapamycin (mTOR) signalling pathway plays a highly conserved role in aging; mice lacking ribosomal protein S6 kinase 1 (S6K1-/-) have extended lifespan and healthspan relative to wild type (WT) controls. Exactly how reduced mTOR signalling induces such effects is unclear, although preservation of stem cell function may be important. We show, using gene expression analyses, that there was a reduction in expression of cell cycle genes in young (12 week) and aged (80 week) S6K1-/- BM-derived c-Kit+ cells when compared to age-matched WT mice, suggesting that these cells are more quiescent in S6K1-/- mice. In addition, we investigated hematopoietic stem cell (HSC) frequency and function in young and aged S6K1-/- and WT mice. Young, but not aged, S6K1-/- mice had more LSK (lineage-, c-Kit+, Sca-1+) cells (% of bone marrow (BM)), including the most primitive long-term repopulating HSC (LT-HSC) relative to WT controls. Donor-derived engraftment of LT-HSCs in recipient mice was unaffected by genotype in young mice, but was enhanced in transplants using LT-HSCs derived from aged S6K1-/- mice. Our results are the first to provide evidence that age-associated HSC functional decline is ameliorated in a long-lived mTOR mutant mouse

Voltage-controlled electron tunnelling from a single self-assembled quantum dot embedded in a two-dimensional-electron-gas-based photovoltaic cell

We perform high-resolution photocurrent (PC) spectroscopy to investigate resonantly the neutral exciton ground-state (X0) in a single InAs/GaAs self-assembled quantum dot (QD) embedded in the intrinsic region of an n-i-Schottky photodiode based on a two-dimensional electron gas (2DEG), which was formed from a Si delta-doped GaAs layer. Using such a device, a single-QD PC spectrum of X0 is measured by sweeping the bias-dependent X0 transition energy through that of a fixed narrow-bandwidth laser via the quantum-confined Stark effect (QCSE). By repeating such a measurement for a series of laser energies, a precise relationship between the X0 transition energy and bias voltage is then obtained. Taking into account power broadening of the X0 absorption peak, this allows for high-resolution measurements of the X0 homogeneous linewidth and, hence, the electron tunnelling rate. The electron tunnelling rate is measured as a function of the vertical electric field and described accurately by a theoretical model, yielding information about the electron confinement energy and QD height. We demonstrate that our devices can operate as 2DEG-based QD photovoltaic cells and conclude by proposing two optical spintronic devices that are now feasible.Comment: 34 pages, 11 figure

Realisation of Hardy's Thought Experiment

We present an experimental realisation of Hardy's thought experiment [Phys. Rev. Lett. {\bf 68}, 2981 (1992)], using photons. The experiment consists of a pair of Mach-Zehnder interferometers that interact through photon bunching at a beam splitter. A striking contradiction is created between the predictions of quantum mechanics and local hidden variable based theories. The contradiction relies on non-maximally entangled position states of two particles.Comment: 5 page

Real-time compression of IEC 61869-9 sampled value data

Fast-acting, yet cost-effective, communications is critical for smarter grid monitoring, protection, and control. This paper demonstrates a new approach for the real-time compression of Sampled Value (SV) data based on the IEC 61869-9 recommendations. This approach applies simple compression rules, yet yields excellent compression performance---typically compressing data to less than half of the original size. This leads to a significant and beneficial reduction in encoding time (in the merging unit producing the SV data) and decoding time (at the end application), as well as the main benefit of reduced Ethernet transmission times resulting from the reduced frame size. As well as reducing the absolute bandwidth requirements in typical applications, this has system-wide benefits due to reducing Ethernet queuing delays and the consequent network jitter. The approach has been validated on a real-time platform to accurately measure all contributions to the end-to-end delay. This work will help enable low-latency and bandwidth-sensitive applications involving the SV protocol, such as phasor measurement units and wide-area protection

Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors

Biocompatible polymer solutions that can crosslink in situ following injection to form stable hydrogels are of interest as depots for sustained delivery of therapeutic factors or cells, and as scaffolds for regenerative medicine. Here, injectable self-gelling alginate formulations obtained by mixing alginate microspheres (as calcium reservoirs) with soluble alginate solutions were characterized for potential use in immunotherapy. Rapid redistribution of calcium ions from microspheres into the surrounding alginate solution led to crosslinking and formation of stable hydrogels. The mechanical properties of the resulting gels correlated with the concentration of calcium-reservoir microspheres added to the solution. Soluble factors such as the cytokine interleukin-2 were readily incorporated into self-gelling alginate matrices by simply mixing them with the formulation prior to gelation. Using alginate microspheres as modular components, strategies for binding immunostimulatory CpG oligonucleotides onto the surface of microspheres were also demonstrated. When injected subcutaneously in the flanks of mice, self-gelling alginate formed soft macroporous gels supporting cellular infiltration and allowing ready access to microspheres carrying therapeutic factors embedded in the matrix. This in situ gelling formulation may thus be useful for stimulating immune cells at desired locales, such as solid tumors or infection sites, as well as for other soft tissue regeneration applications.United States. Defense Advanced Research Projects Agency (Contract W81XWH-04-C-0139)National Institutes of Health (U.S.) (EB007280-02)National Science Foundation (U.S.) (Award 0348259