1,098 research outputs found
Tsallis statistics generalization of non-equilibrium work relations
We use third constraint formulation of Tsallis statistics and derive the
-statistics generalization of non-equilibrium work relations such as the
Jarzynski equality and the Crooks fluctuation theorem which relate the free
energy differences between two equilibrium states and the work distribution of
the non-equilibrium processes.Comment: 5 page
ONSAGER RELATIONS AND EXTENDED IRREVERSIBLE THERMODYNAMICS
We show that when the thermodynamic fluxes are included as independent thermodynamic state variables of a generalized entropy. the original ONSAGER formulation may be directly used in the space of the fiuxes. Therefore, the ONSAGER relations may be derived either in the space of the classical (slow) variables, by using a spatial FOURIER transformation, or in the space of the non-classical (fast) variables such as the physical fiuxes, without need of any Fourier transform. Furthermore. we analyse the question of non-linear ONSAGER relations by studying one particular set of evolution equations of the fiuxes, and considering the fluctuations of the fluxes around a non-equilibrium steady
state. Comparison with kinetic theory is not completely conclusive, because of several open questions which we comment in the concluding remarks
Status of QCD
I have been asked to discuss the status of QCD. It seems to me that there are
three main points to be made about the present status of QCD: QCD is
right, and we can do many beautiful things with it. There are several
important concrete problems that lie just beyond the edge of our current
understanding. There are some foundational issues in QCD, and some
recent developments, that may point toward entirely new directions. These
points will, I believe, emerge quite clearly from the following more detailed
discussion. The discussion will be in three parts. I'll first discuss
elementary processes, then more complicated processes, and then finally
foundational issues.Comment: 28 pages, use Phyzzx, figures available by FAX or mail on request,
IASSNS-HEP-93/6
Influence of surfactants on the structure of titanium oxide gels : experiments and simulations
We report here on experimental and numerical studies of the influence of
surfactants on mineral gel synthesis. The modification of the gel structure
when the ratios water-precursor and water-surfactant vary is brought to the
fore by fractal dimension measures. A property of {\em polydispersity of the
initial hydrolysis} is proposed to explain these results, and is successfuly
tested through numerical experiments of three dimensional chemically limited
aggregation.Comment: 12 pages, 4 Postscript figures, uses RevTe
Detection of human bocavirus in children with Kawasaki disease
ABSTRACTHuman bocavirus (HboV) is an emerging virus that has been implicated as a cause of acute upper and lower respiratory tract infection in children. As no serological assay is available, PCR was used to screen nasopharyngeal, serum or stool samples from 16 patients with Kawasaki disease for HBoV nucleic acid. HBoV was identified by PCR in five (31.2%) patients, suggesting that this emerging virus may also play a pathogenic role in some cases of Kawasaki disease
Liver and brain differential expression of one-carbon metabolism genes during ontogenesis
One-carbon metabolism (1C metabolism) is of paramount importance for cell metabolism and mammalian development. It is involved in the synthesis or modification of a wide variety of compounds such as proteins, lipids, purines, nucleic acids and neurotransmitters. We describe here the evolution of expression of genes related to 1C metabolism during liver and brain ontogeny in mouse. The level of expression of 30 genes involved in 1C metabolism was quantified by RT-qPCR in liver and brain tissues of OF1 mice at E9, E11, E13, E15, E17, P0, P3, P5, P10, P15 developmental stages and in adults. In the liver, hierarchical clustering of the gene expression patterns revealed five distinct clades of genes with a first bifurcating hierarchy distinguishing two main developmental stages before and after E15. In the brain most of the 1C metabolism genes are expressed but at a lower levels. The gene expression of enzymes involved in 1C metabolism show dramatic changes during development that are tissue specific. mRNA expression patterns of all major genes involved in 1C metabolism in liver and brain provide clues about the methylation demand and methylation pathways during embryonic development
Why did Swiss citizens vote to ban tobacco advertising?
In February 2022, Swiss citizens agreed to modify the Swiss Constitution to ban tobacco advertising reaching children and adolescents. This case study analyses the arguments used by both opponents and supporters of the constitutional amendment. Opponents argued that the proposed regulation went too far, threatened the economy, restricted personal freedom, was superfluous as the current law already protected youth and that it opened the door to marketing bans of other harmful products. Proponents focused on youth protection and invoked the burden of smoking on public health and the fact that advertising bans are an effective evidence-based measure. A comparison with previous campaigns to ban tobacco advertising that had failed suggests factors accounting for the positive vote in 2022. These include the strategic framing of youth protection, the separation of tobacco from other issues (such as alcohol advertising), the deteriorating image of the tobacco industry and the ability of the proponents to mobilise a broad coalition of health and youth organisations, with improved funding and communication. The lessons may be instructive for other campaigns seeking to regulate commercial determinants of health
General Non-equilibrium Theory of Colloid Dynamics
A non-equilibrium extension of Onsager's canonical theory of thermal
fluctuations is employed to derive a self-consistent theory for the description
of the statistical properties of the instantaneous local concentration profile
n(r,t) of a colloidal liquid in terms of the coupled time evolution equations
of its mean value n(r,t) and of the covariance {\sigma}(r,r';t) \equiv
of its fluctuations {\delta}n(r, t) = n(r, t) -
n(r, t). These two coarse-grained equations involve a local mobility function
b(r, t) which, in its turn, is written in terms of the memory function of the
two-time correlation function C(r, r' ; t, t') \equiv <{\delta}n(r,
t){\delta}n(r',t')>. For given effective interactions between colloidal
particles and applied external fields, the resulting self-consistent theory is
aimed at describing the evolution of a strongly correlated colloidal liquid
from an initial state with arbitrary mean and covariance n^0(r) and
{\sigma}^0(r,r') towards its equilibrium state characterized by the equilibrium
local concentration profile n^(eq)(r) and equilibrium covariance
{\sigma}^(eq)(r,r').
This theory also provides a general theoretical framework to describe
irreversible processes associated with dynamic arrest transitions, such as
aging, and the effects of spatial heterogeneities
Is there an association between wheezing and constipation in preschool children? Explanations from a longitudinal birth cohort
Objective: To assess whether wheezing and atopic dermatitis were associated with constipation in preschool children and to what extent shared risk factors contribute to this relationship. Methods: A population-based sample of 4651 preschool children was used. At the age of 24, 36 and 48 months, a parental report of functional constipation was available according to the Rome II criteria, and data on atopic dermatitis and wheezing were available using age-adapted questionnaires from the International Study of Asthma and Allergie
The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation
We thank Manuel Kulagin for technical help, Pierre Bonnaventure for portal vein blood sampling, Francisco Sepulveda for technical assistance in GS-MS acquisition, and Dorothee Hahne (Metabolomics Australia, University of Western Australia) for human samples SCFA isolation, acquisition, and analysis. We also thank Cristina Cartoni (Phenotyping Unit, EPFL) for Milliplex analysis, Jessica Dessimoz and her team from the Histology Core Facility (EPFL), Miguel Garcia and his team from the Flow Cytometry Core Facility (EPFL), and staff from the EPFL CPG animal house for excellent animal care. The computations were partially performed at the Vital-IT Center for high-performance computing of the SIB Swiss Institute of Bioinformatics (http://www.vital-it.ch). The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013) / ERC Grant Agreement n. 310948. Funding for A.W.W. and a subset of the 16S rRNA gene sequencing was provided by the Wellcome Trust (grant number WT 098051). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD
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