Comments on "Wall-plug (AC) power consumption of a very high energy e+/e- storage ring collider" by Marc Ross

The paper arXiv:1308.0735 questions some of the technical assumptions made by the TLEP Steering Group when estimating in arXiv:1305.6498 the power requirement for the very high energy e+e- storage ring collider TLEP. We show that our assumptions are based solidly on CERN experience with LEP and the LHC, as well accelerators elsewhere, and confirm our earlier baseline estimate of the TLEP power consumption.Comment: 6 page

Experimental study of the uptake of water by soybean roots

The water extraction from soil by plant roots was treated by assuming that such extraction could be represented as a continuously distributed sink (negative source) function. Preliminary results with soybeans grown in soil columns showed that a small part of the root system could extract most of the water used in transpiration. Root density as measured by root length per unit volume of soil was not directly correlated with water uptake. Both the hydraulic conductivity of the soil and root density played a major role in determining the rate of extraction of water at a given depth in the soil. Water uptake per unit root length ranged up to about 0.5 cm3/cm of root/day. This kind of data gives more insight into the conditions at the root-soil interface. The experimental work in this project was developed from a numerical analysis which was supported by an earlier OWRR project (Project No. 65-O3G), and is an example of a basic approach to the study of the interaction of the plant with its environment in which the available degree of understanding of the water flow process in soil is brought to bear upon the plant-soil interaction. The importance of evapotranspiration is well known in the hydrologic cycle. The experimental work described in this report makes a further contribution toward our understanding of this process.U.S. Geological SurveyU.S. Department of the InteriorOpe

Observation of coasting beam at the HERA Proton--Ring

We present data collected with the HERA-B wire target which prove the existence of coasting beam at the HERA proton storage ring. The coasting beam is inherently produced by the proton machine operation and is not dominated by target effects.Comment: 17 pages (Latex), 12 figures (Enc. Postscript

Planning the Future of U.S. Particle Physics (Snowmass 2013): Chapter 6: Accelerator Capabilities

These reports present the results of the 2013 Community Summer Study of the APS Division of Particles and Fields ("Snowmass 2013") on the future program of particle physics in the U.S. Chapter 6, on Accelerator Capabilities, discusses the future progress of accelerator technology, including issues for high-energy hadron and lepton colliders, high-intensity beams, electron-ion colliders, and necessary R&D for future accelerator technologies.Comment: 26 page

Prospects for the Search for a Standard Model Higgs Boson in ATLAS using Vector Boson Fusion

The potential for the discovery of a Standard Model Higgs boson in the mass range m_H < 2 m_Z in the vector boson fusion mode has been studied for the ATLAS experiment at the LHC. The characteristic signatures of additional jets in the forward regions of the detector and of low jet activity in the central region allow for an efficient background rejection. Analyses for the H -> WW and H -> tau tau decay modes have been performed using a realistic simulation of the expected detector performance. The results obtained demonstrate the large discovery potential in the H -> WW decay channel and the sensitivity to Higgs boson decays into tau-pairs in the low-mass region around 120 GeV.Comment: 20 pages, 13 ps figures, uses EPJ style fil

A High Luminosity e+e- Collider to study the Higgs Boson

A strong candidate for the Standard Model Scalar boson, H(126), has been discovered by the Large Hadron Collider (LHC) experiments. In order to study this fundamental particle with unprecedented precision, and to perform precision tests of the closure of the Standard Model, we investigate the possibilities offered by An e+e- storage ring collider. We use a design inspired by the B-factories, taking into account the performance achieved at LEP2, and imposing a synchrotron radiation power limit of 100 MW. At the most relevant centre-of-mass energy of 240 GeV, near-constant luminosities of 10^34 cm^{-2}s^{-1} are possible in up to four collision points for a ring of 27km circumference. The achievable luminosity increases with the bending radius, and for 80km circumference, a luminosity of 5 10^34 cm^{-2}s^{-1} in four collision points appears feasible. Beamstrahlung becomes relevant at these high luminosities, leading to a design requirement of large momentum acceptance both in the accelerating system and in the optics. The larger machine could reach the top quark threshold, would yield luminosities per interaction point of 10^36 cm^{-2}s^{-1} at the Z pole (91 GeV) and 2 10^35 cm^{-2}s^{-1} at the W pair production threshold (80 GeV per beam). The energy spread is reduced in the larger ring with respect to what is was at LEP, giving confidence that beam polarization for energy calibration purposes should be available up to the W pair threshold. The capabilities in term of physics performance are outlined.Comment: Submitted to the European Strategy Preparatory Group 01-04-2013 new version as re-submitted to PRSTA

Machine Learning Analyses of Highly-Multiplexed Immunofluorescence Identifies Distinct Tumor and Stromal Cell Populations in Primary Pancreatic Tumors

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a formidable challenge for patients and clinicians. OBJECTIVE: To analyze the distribution of 31 different markers in tumor and stromal portions of the tumor microenvironment (TME) and identify immune cell populations to better understand how neoplastic, non-malignant structural, and immune cells, diversify the TME and influence PDAC progression. METHODS: Whole slide imaging (WSI) and cyclic multiplexed-immunofluorescence (MxIF) was used to collect 31 different markers over the course of nine distinctive imaging series of human PDAC samples. Image registration and machine learning algorithms were developed to largely automate an imaging analysis pipeline identifying distinct cell types in the TME. RESULTS: A random forest algorithm accurately predicted tumor and stromal-rich areas with 87% accuracy using 31 markers and 77% accuracy using only five markers. Top tumor-predictive markers guided downstream analyses to identify immune populations effectively invading into the tumor, including dendritic cells, CD4+ T cells, and multiple immunoregulatory subtypes. CONCLUSIONS: Immunoprofiling of PDAC to identify differential distribution of immune cells in the TME is critical for understanding disease progression, response and/or resistance to treatment, and the development of new treatment strategies

Hierarchical Multimodel Ensemble Estimates of Soil Water Retention with Global Coverage

A correct quantification of mass and energy exchange processes among land surface and atmosphere requires an accurate description of unsaturated soil hydraulic properties. Soil pedotransfer functions (PTFs) have been widely used to predict soil hydraulic parameters. Here, 13 PTFs were grouped according to input data requirements and evaluated against a well-documented soil database with global coverage. Weighted ensembles (calibrated by four groups and the full 13-member set of PTFs) were shown to have improved performance over individual PTFs in terms of root mean square error and other model selection criteria. Global maps of soil water retention data from the ensemble models as well as their uncertainty were provided. These maps demonstrate that five PTF ensembles tend to have different estimates, especially in middle and high latitudes in the Northern Hemisphere. Our full 13-member ensemble model provides more accurate estimates than PTFs that are currently being used in earth system models

Distinguishing Various Models of the 125 GeV Boson in Vector Boson Fusion

The hint of a new particle around 125 GeV at the LHC through the decay modes of diphoton and a number of others may point to quite a number of possibilities. While at the LHC the dominant production mechanism for the Higgs boson of the standard model and some other extensions is via the gluon fusion process, the alternative vector boson fusion is more sensitive to electroweak symmetry breaking through the gauge-Higgs couplings and therefore can be used to probe for models beyond the standard model. In this work, using the well known dijet-tagging technique to single out the vector boson fusion mechanism, we investigate its capability to discriminate a number of models that have been suggested to give an enhanced inclusive diphoton production rate, including the standard model Higgs boson, fermiophobic Higgs boson, Randall-Sundrum radion, inert-Higgs-doublet model, two-Higgs-doublet model, and the MSSM. The rates in vector-boson fusion can give more information of the underlying models to help distinguishing among the models.Comment: 31 pages, 3 figures; in this version some wordings are change

Simplified Multistep Outflow Method to Estimate Unsaturated Hydraulic Functions for Coarse-Textured Soils

Although the multistep outfl ow (MSO) method is well suited for the estimation of soil hydraulic properties by inverse solution techniques, this method has not been widely adopted because it requires advanced instrumentation and is time consuming. Th e objective of this study was to develop a modifi ed version of the multistep outfl ow technique that largely simplifi es laboratory procedures and reduces costs and time. Th e numerical inversion procedures require applying user-friendly HYDRUS soft ware to estimate fi tting parameters for soil water retention and unsaturated hydraulic conductivity curves. Whereas values of saturated water content and saturated hydraulic conductivity must be measured independently, the remaining functional parameters are estimated using an inverse solution of a transient drainage experiment using multiple suction steps and a hanging water column, with drainage outfl ows measured during drainage. A comparison test showed that the simplifi ed experiment without tensiometric measurements provided suffi cient information in the parameter identifi cation compared with a traditional pressure outfl ow experiment with tensiometric measurements for an Oso Flaco sand and a loamy sand fi eld soil in the suction range of 0 to 17 kPa