Bevalac calibration of the SOFIE range and hodoscope detectors

The scintillating optical fiber isotope experiment (SOFIE) is a Cerenkov-dE/dx-Range experiment which was developed initially for balloon flight to study the isotopic composition of cosmic rays in the iron region. The electronic range and hodoscope detectors use scintillating optical fibers to image the tracks of stopping charged particles and to determine their trajectory. The particle range is determined and used together with a Cerenkov measurement to determine the mass of the stopping particle. Preliminary results of a Bevalac calibration performed in August, 1984 with a prototype of the balloon flight instrument, to study the measurement precision in range and trajectory which could be attained with this detector are described

Relative abundances of elements (20 or = Z or = 28) at energies up to 70 GeV/amu using relativistic rise in ion chambers

The results of a new balloon borne cosmic ray detector flown from Palestine, TX in Sept., 1982 are discussed. The exposure of 62 square meter-ster-hr is sufficient to prove the concept of using gas ionization chambers as energy measuring devices in the relativistic rise region. The abundances, relative Fe-26, of the pure secondaries Cr-22 and Ti-24, the pure primary Ni26, and the mixed primary and secondary Ca-20 between 6 and 70GeV/amu were measured

Observation of VH and VVH cosmic rays with an ionization-Cerenkov detector system

Heavy and ultraheavy nuclei observations of cosmic rays using ionization chamber-Cerenkov counter syste

The origin and propagation of VVH primary cosmic ray particles

Several source spectra were constructed from combinations of 4- and s-process nuclei to match the observed charge spectrum of VVH particles. Their propagation was then followed, allowing for interactions and decay, and comparisons were made between the calculated near-earth spectra and those observed during high altitude balloon flights. None of the models gave good agreement with observations

Large area pulse ionization chamber for measurement of extremely heavy cosmic rays

Parallel plate ionization chamber for identifying relativistic cosmic ray nucle

Primary cosmic ray particles with z 35 (VVH particles)

Large areas of nuclear emulsions and plastic detectors were exposed to the primary cosmic radiation during high altitude balloon flights. From the analysis of 141 particle tracks recorded during a total exposure of 1.3 x 10 to the 7th power sq m ster.sec., a charge spectrum of the VVH particles has been derived

Scintillator-fiber charged particle track-imaging detector

A scintillator-fiber charged-particle track-imaging detector was developed using a bundle of square cross section plastic scintillator fiber optics, proximity focused onto an image intensified charge injection device (CID) camera. The tracks of charged particle penetrating into the scintillator fiber bundle are projected onto the CID camera and the imaging information is read out in video format. The detector was exposed to beams of 15 MeV protons and relativistic Neon, Manganese, and Gold nuclei and images of their tracks were obtained. Details of the detector technique, properties of the tracks obtained, and preliminary range measurements of 15 MeV protons stopping in the fiber bundle are presented

Energy spectra of elements with 18 or = Z or = 28 between 10 and 300 GeV/amu

The HEAO-3 Heavy Nuclei Experiment is composed of ionization chambers above and below a plastic Cerenkov counter. The energy dependence of the abundances of elements with atomic number, Z, between 18 and 28 at very high energies where they are rare and thus need the large area x time are measured. The measurements of the Danish-French HEAO-3 experiment (Englemann,, et al., 1983) are extended to higher energies, using the relativistic rise of ionization signal as a measure of energy. Source abundances for Ar and Ca were determined

Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase

Aspartic acid residues comprising the -D-(aa)(n)-Y-L-D-D- DNA polymerase active site triad of reverse transcriptase from the Saccharomyces cerevisiae long terminal repeat-retrotransposon Ty3 (Asp151, Asp213 and Asp214) were evaluated via site-directed mutagenesis. An Asp151→Glu substitution showed a dramatic decrease in catalytic efficiency and a severe translocation defect following initiation of DNA synthesis. In contrast, enzymes harboring the equivalent alteration at Asp213 and Asp214 retained DNA polymerase activity. Asp151→Asn and Asp213→Asn substitutions eliminated both polymerase activities. However, while Asp214 of the triad could be replaced by either Asn or Glu, introducing Gln seriously affected processivity. Mutants of the carboxylate triad at positions 151 and 213 also failed to catalyze pyrophosphorolysis. Finally, alterations to the DNA polymerase active site affected RNase H activity, suggesting a close spatial relationship between these N- and C-terminal catalytic centers. Taken together, our data reveal a critical role for Asp151 and Asp213 in catalysis. In contrast, the second carboxylate of the Y-L-D-D motif (Asp214) is not essential for catalysis, and possibly fulfills a structural role. Although Asp214 was most insensitive to substitution with respect to activity of the recombinant enzyme, all alterations at this position were lethal for Ty3 transposition

The Isotopic Composition of Cosmic Ray Nuclei Beyond the Iron Peak

Isotope measurements of cosmic ray nuclei beyond the Fe peak are considered, using the charge region from Z=29 to Z∼40 as an example. Such studies can address a number of important questions that bear on cosmic ray origin, acceleration, and propagation. One possible approach for measuring isotopes with Z≥30 is based on large‐area arrays of silicon solid state detectors combined with scintillating optical fiber trajectory detectors optical fiber trajectory detectors