292 research outputs found
Faraday effect : a field theoretical point of view
We analyze the structure of the vacuum polarization tensor in the presence of
a background electromagnetic field in a medium. We use various discrete
symmetries and crossing symmetry to constrain the form factors obtained for the
most general case. From these symmetry arguments, we show why the vacuum
polarization tensor has to be even in the background field when there is no
background medium. Taking then the background field to be purely magnetic, we
evaluate the vacuum polarization to linear order in it. The result shows the
phenomenon of Faraday rotation, i.e., the rotation of the plane of polarization
of a plane polarized light passing through this background. We find that the
usual expression for Faraday rotation, which is derived for a non-degenerate
plasma in the non-relativistic approximation, undergoes substantial
modification if the background is degenerate and/or relativistic. We give
explicit expressions for Faraday rotation in completely degenerate and
ultra-relativistic media.Comment: 20 pages, Latex, uses axodraw.st
Identification of prostate-enriched proteins by in-depth proteomic analyses of expressed prostatic secretions in urine
Urinary expressed prostatic secretion or \u201cEPS-urine\u201d is proximal tissue fluid
that is collected after a digital rectal exam (DRE). EPS-urine is a rich source of prostatederived proteins that can be used for biomarker discovery for prostate cancer (PCa) and other prostatic diseases. We previously conducted a comprehensive proteome analysis of direct expressed prostatic secretions (EPS). In the current study, we defined the proteome of EPS-urine employing Multidimensional Protein Identification Technology (MudPIT) and
providing a comprehensive catalogue of this body fluid for future biomarker studies. We
identified 1022 unique proteins in a heterogeneous cohort of 11 EPS-urines derived from biopsy negative noncancer diagnoses with some benign prostatic diseases (BPH) and lowgrade PCa, representative of secreted prostate and immune system-derived proteins in a
urine background. We further applied MudPIT-based proteomics to generate and compare
the differential proteome from a subset of pooled urines (pre-DRE) and EPS-urines (post-
DRE) from noncancer and PCa patients. The direct proteomic comparison of these highly
controlled patient sample pools enabled us to define a list of prostate-enriched proteins detectable in EPS-urine and
distinguishable from a complex urine protein background. A combinatorial analysis of both proteomics data sets and systematic
integration with publicly available proteomics data of related body fluids, human tissue transcriptomic data, and immunohistochemistry images from the Human Protein Atlas database allowed us to demarcate a robust panel of 49 prostate-derived proteins in EPS-urine. Finally, we validated the expression of seven of these proteins using Western blotting, supporting the likelihood that they originate from the prostate. The definition of these prostatic proteins in EPS-urine samples provides a
reference for future investigations for prostatic-disease biomarker studies
Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells
Background: During the maternal-to-zygotic transition (MZT) vast changes in the embryonic transcriptome are produced by a combination of two processes: elimination of maternally provided mRNAs and synthesis of new transcripts from the zygotic genome. Previous genome-wide analyses of the MZT have been restricted to whole embryos. Here we report the first such analysis for primordial germ cells (PGCs), the progenitors of the germ-line stem cells. Results: We purified PGCs from Drosophila embryos, defined their proteome and transcriptome, and assessed the content, scale and dynamics of their MZT. Transcripts encoding proteins that implement particular types of biological functions group into nine distinct expression profiles, reflecting coordinate control at the transcriptional and posttranscriptional levels. mRNAs encoding germ-plasm components and cell-cell signaling molecules are rapidly degraded while new transcription produces mRNAs encoding the core transcriptional and protein synthetic machineries. The RNA-binding protein Smaug is essential for the PGC MZT, clearing transcripts encoding proteins that regulate stem cell behavior, transcriptional and posttranscriptional processes. Computational analyses suggest that Smaug and AU-rich element binding proteins function independently to control transcript elimination. Conclusions: The scale of the MZT is similar in the soma and PGCs. However, the timing and content of their MZTs differ, reflecting the distinct developmental imperatives of these cell types. The PGC MZT is delayed relative to that in the soma, likely because relief of PGC-specific transcriptional silencing is required for zygotic genome activation as well as for efficient maternal transcript clearance.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305391700004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Biotechnology & Applied MicrobiologyGenetics & HereditySCI(E)20ARTICLE2null1
Light Cone Condition for a Thermalized QED Vacuum
Within the QED effective action approach, we study the propagation of
low-frequency light at finite temperature. Starting from a general effective
Lagrangian for slowly varying fields whose structure is solely dictated by
Lorentz covariance and gauge invariance, we derive the light cone condition for
light propagating in a thermalized QED vacuum. As an application, we calculate
the velocity shifts, i.e., refractive indices of the vacuum, induced by
thermalized fermions to one loop. We investigate various temperature domains
and also include a background magnetic field. While low-temperature effects to
one loop are exponentially damped by the electron mass, there exists a maximum
velocity shift of in the
intermediate-temperature domain .Comment: 9 pages, 3 figures, REVTeX, typos corrected, final version to appear
in Phys. Rev.
Pion propagation in the linear sigma model at finite temperature
We construct effective one-loop vertices and propagators in the linear sigma
model at finite temperature, satisfying the chiral Ward identities and thus
respecting chiral symmetry, treating the pion momentum, pion mass and
temperature as small compared to the sigma mass. We use these objects to
compute the two-loop pion self-energy. We find that the perturbative behavior
of physical quantities, such as the temperature dependence of the pion mass, is
well defined in this kinematical regime in terms of the parameter
m_pi^2/4pi^2f_pi^2 and show that an expansion in terms of this reproduces the
dispersion curve obtained by means of chiral perturbation theory at leading
order. The temperature dependence of the pion mass is such that the first and
second order corrections in the above parameter have the same sign. We also
study pion damping both in the elastic and inelastic channels to this order and
compute the mean free path and mean collision time for a pion traveling in the
medium before forming a sigma resonance and find a very good agreement with the
result from chiral perturbation theory when using a value for the sigma mass of
600 MeV.Comment: 18 pages, 11 figures, uses RevTeX and epsfig. Expanded conclusions,
added references. To appear in Phys. Rev.
Signal of Quark Deconfinement in the Timing Structure of Pulsar Spin-Down
The conversion of nuclear matter to quark matter in the core of a rotating
neutron star alters its moment of inertia. Hence the epoch over which
conversion takes place will be signaled in the spin-down "signal_prl.tex" 581
lines, 22203 characters characteristics of pulsars. We find that an observable
called the braking index should be easily measurable during the transition
epoch and can have a value far removed (by orders of magnitude) from the
canonical value of three expected for magnetic dipole radiation, and may have
either sign. The duration of the transition epoch is governed by the slow loss
of angular momentum to radiation and is further prolonged by the reduction in
the moment of inertia caused by the phase change which can even introduce an
era of spin-up. We estimate that about one in a hundred pulsars may be passing
through this phase. The phenomenon is analogous to ``bachbending'' observed in
the moment of inertia of rotating nuclei observed in the 1970's, which also
signaled a change in internal structure with changing spin.Comment: 5 pages, 4 figures, Revtex. (May 12, 1997, submitted to PRL
Viscosities of Quark-Gluon Plasmas
The quark and gluon viscosities are calculated in quark-gluon plasmas to
leading orders in the coupling constant by including screening. For weakly
interaction QCD and QED plasmas dynamical screening of transverse interactions
and Debye screening of longitudinal interactions controls the infrared
divergences. For strongly interacting plasmas other screening mechanisms taken
from lattice calculations are employed. By solving the Boltzmann equation for
quarks and gluons including screening the viscosity is calculated to leading
orders in the coupling constant. The leading logarithmic order is calculated
exactly by a full variational treatment. The next to leading orders are found
to be very important for sizable coupling constants as those relevant for the
transport properties relevant for quark-gluon plasmas created in relativistic
heavy ion collisions and the early universe.Comment: 12 pages + 6 figures, report LBL-3492
Perturbation Theory with a Variational Basis: the Generalized Gaussian Effective Potential
The perturbation theory with a variational basis is constructed and
analyzed.The generalized Gaussian effective potential is introduced and
evaluated up to the second order for selfinteracting scalar fields in one and
two spatial dimensions. The problem of the renormalization of the mass is
discussed in details. Thermal corrections are incorporated. The comparison
between the finite temperature generalized Gaussian effective potential and the
finite temperature effective potential is critically analyzed. The phenomenon
of the restoration at high temperature of the symmetry broken at zero
temperature is discussed.Comment: RevTex, 49 pages, 16 eps figure
Restricting quark matter models by gravitational wave observation
We consider the possibilities for obtaining information about the equation of
state for quark matter by using future direct observational data on
gravitational waves. We study the nonradial oscillations of both fluid and
spacetime modes of pure quark stars. If we observe the and the lowest
modes from quark stars, by using the simultaneously obtained
radiation radius we can constrain the bag constant with reasonable
accuracy, independently of the quark mass.Comment: To appear in Phys. Rev.
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