292 research outputs found

    Faraday effect : a field theoretical point of view

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    We analyze the structure of the vacuum polarization tensor in the presence of a background electromagnetic field in a medium. We use various discrete symmetries and crossing symmetry to constrain the form factors obtained for the most general case. From these symmetry arguments, we show why the vacuum polarization tensor has to be even in the background field when there is no background medium. Taking then the background field to be purely magnetic, we evaluate the vacuum polarization to linear order in it. The result shows the phenomenon of Faraday rotation, i.e., the rotation of the plane of polarization of a plane polarized light passing through this background. We find that the usual expression for Faraday rotation, which is derived for a non-degenerate plasma in the non-relativistic approximation, undergoes substantial modification if the background is degenerate and/or relativistic. We give explicit expressions for Faraday rotation in completely degenerate and ultra-relativistic media.Comment: 20 pages, Latex, uses axodraw.st

    Identification of prostate-enriched proteins by in-depth proteomic analyses of expressed prostatic secretions in urine

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    Urinary expressed prostatic secretion or \u201cEPS-urine\u201d is proximal tissue fluid that is collected after a digital rectal exam (DRE). EPS-urine is a rich source of prostatederived proteins that can be used for biomarker discovery for prostate cancer (PCa) and other prostatic diseases. We previously conducted a comprehensive proteome analysis of direct expressed prostatic secretions (EPS). In the current study, we defined the proteome of EPS-urine employing Multidimensional Protein Identification Technology (MudPIT) and providing a comprehensive catalogue of this body fluid for future biomarker studies. We identified 1022 unique proteins in a heterogeneous cohort of 11 EPS-urines derived from biopsy negative noncancer diagnoses with some benign prostatic diseases (BPH) and lowgrade PCa, representative of secreted prostate and immune system-derived proteins in a urine background. We further applied MudPIT-based proteomics to generate and compare the differential proteome from a subset of pooled urines (pre-DRE) and EPS-urines (post- DRE) from noncancer and PCa patients. The direct proteomic comparison of these highly controlled patient sample pools enabled us to define a list of prostate-enriched proteins detectable in EPS-urine and distinguishable from a complex urine protein background. A combinatorial analysis of both proteomics data sets and systematic integration with publicly available proteomics data of related body fluids, human tissue transcriptomic data, and immunohistochemistry images from the Human Protein Atlas database allowed us to demarcate a robust panel of 49 prostate-derived proteins in EPS-urine. Finally, we validated the expression of seven of these proteins using Western blotting, supporting the likelihood that they originate from the prostate. The definition of these prostatic proteins in EPS-urine samples provides a reference for future investigations for prostatic-disease biomarker studies

    Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells

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    Background: During the maternal-to-zygotic transition (MZT) vast changes in the embryonic transcriptome are produced by a combination of two processes: elimination of maternally provided mRNAs and synthesis of new transcripts from the zygotic genome. Previous genome-wide analyses of the MZT have been restricted to whole embryos. Here we report the first such analysis for primordial germ cells (PGCs), the progenitors of the germ-line stem cells. Results: We purified PGCs from Drosophila embryos, defined their proteome and transcriptome, and assessed the content, scale and dynamics of their MZT. Transcripts encoding proteins that implement particular types of biological functions group into nine distinct expression profiles, reflecting coordinate control at the transcriptional and posttranscriptional levels. mRNAs encoding germ-plasm components and cell-cell signaling molecules are rapidly degraded while new transcription produces mRNAs encoding the core transcriptional and protein synthetic machineries. The RNA-binding protein Smaug is essential for the PGC MZT, clearing transcripts encoding proteins that regulate stem cell behavior, transcriptional and posttranscriptional processes. Computational analyses suggest that Smaug and AU-rich element binding proteins function independently to control transcript elimination. Conclusions: The scale of the MZT is similar in the soma and PGCs. However, the timing and content of their MZTs differ, reflecting the distinct developmental imperatives of these cell types. The PGC MZT is delayed relative to that in the soma, likely because relief of PGC-specific transcriptional silencing is required for zygotic genome activation as well as for efficient maternal transcript clearance.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305391700004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Biotechnology & Applied MicrobiologyGenetics & HereditySCI(E)20ARTICLE2null1

    Light Cone Condition for a Thermalized QED Vacuum

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    Within the QED effective action approach, we study the propagation of low-frequency light at finite temperature. Starting from a general effective Lagrangian for slowly varying fields whose structure is solely dictated by Lorentz covariance and gauge invariance, we derive the light cone condition for light propagating in a thermalized QED vacuum. As an application, we calculate the velocity shifts, i.e., refractive indices of the vacuum, induced by thermalized fermions to one loop. We investigate various temperature domains and also include a background magnetic field. While low-temperature effects to one loop are exponentially damped by the electron mass, there exists a maximum velocity shift of −ήvmax2=α/(3π)-\delta v^2_{max}=\alpha/(3\pi) in the intermediate-temperature domain T∌mT\sim m.Comment: 9 pages, 3 figures, REVTeX, typos corrected, final version to appear in Phys. Rev.

    Pion propagation in the linear sigma model at finite temperature

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    We construct effective one-loop vertices and propagators in the linear sigma model at finite temperature, satisfying the chiral Ward identities and thus respecting chiral symmetry, treating the pion momentum, pion mass and temperature as small compared to the sigma mass. We use these objects to compute the two-loop pion self-energy. We find that the perturbative behavior of physical quantities, such as the temperature dependence of the pion mass, is well defined in this kinematical regime in terms of the parameter m_pi^2/4pi^2f_pi^2 and show that an expansion in terms of this reproduces the dispersion curve obtained by means of chiral perturbation theory at leading order. The temperature dependence of the pion mass is such that the first and second order corrections in the above parameter have the same sign. We also study pion damping both in the elastic and inelastic channels to this order and compute the mean free path and mean collision time for a pion traveling in the medium before forming a sigma resonance and find a very good agreement with the result from chiral perturbation theory when using a value for the sigma mass of 600 MeV.Comment: 18 pages, 11 figures, uses RevTeX and epsfig. Expanded conclusions, added references. To appear in Phys. Rev.

    Signal of Quark Deconfinement in the Timing Structure of Pulsar Spin-Down

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    The conversion of nuclear matter to quark matter in the core of a rotating neutron star alters its moment of inertia. Hence the epoch over which conversion takes place will be signaled in the spin-down "signal_prl.tex" 581 lines, 22203 characters characteristics of pulsars. We find that an observable called the braking index should be easily measurable during the transition epoch and can have a value far removed (by orders of magnitude) from the canonical value of three expected for magnetic dipole radiation, and may have either sign. The duration of the transition epoch is governed by the slow loss of angular momentum to radiation and is further prolonged by the reduction in the moment of inertia caused by the phase change which can even introduce an era of spin-up. We estimate that about one in a hundred pulsars may be passing through this phase. The phenomenon is analogous to ``bachbending'' observed in the moment of inertia of rotating nuclei observed in the 1970's, which also signaled a change in internal structure with changing spin.Comment: 5 pages, 4 figures, Revtex. (May 12, 1997, submitted to PRL

    Viscosities of Quark-Gluon Plasmas

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    The quark and gluon viscosities are calculated in quark-gluon plasmas to leading orders in the coupling constant by including screening. For weakly interaction QCD and QED plasmas dynamical screening of transverse interactions and Debye screening of longitudinal interactions controls the infrared divergences. For strongly interacting plasmas other screening mechanisms taken from lattice calculations are employed. By solving the Boltzmann equation for quarks and gluons including screening the viscosity is calculated to leading orders in the coupling constant. The leading logarithmic order is calculated exactly by a full variational treatment. The next to leading orders are found to be very important for sizable coupling constants as those relevant for the transport properties relevant for quark-gluon plasmas created in relativistic heavy ion collisions and the early universe.Comment: 12 pages + 6 figures, report LBL-3492

    Perturbation Theory with a Variational Basis: the Generalized Gaussian Effective Potential

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    The perturbation theory with a variational basis is constructed and analyzed.The generalized Gaussian effective potential is introduced and evaluated up to the second order for selfinteracting scalar fields in one and two spatial dimensions. The problem of the renormalization of the mass is discussed in details. Thermal corrections are incorporated. The comparison between the finite temperature generalized Gaussian effective potential and the finite temperature effective potential is critically analyzed. The phenomenon of the restoration at high temperature of the symmetry broken at zero temperature is discussed.Comment: RevTex, 49 pages, 16 eps figure

    Restricting quark matter models by gravitational wave observation

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    We consider the possibilities for obtaining information about the equation of state for quark matter by using future direct observational data on gravitational waves. We study the nonradial oscillations of both fluid and spacetime modes of pure quark stars. If we observe the ff and the lowest wIIw_{\rm II} modes from quark stars, by using the simultaneously obtained radiation radius we can constrain the bag constant BB with reasonable accuracy, independently of the ss quark mass.Comment: To appear in Phys. Rev.
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