Antibody response to streptococcal cell wall antigens associated with experimental arthritis in rats.

The antibody response to group A streptococcal cell wall components was measured in rats during the development of chronic, remittent experimental arthritis. The arthritis was induced by a single intraperitoneal injection of an aqueous suspension of group A streptococcal cell wall fragments and antibodies were measured by a radioactive antigen-binding assay. Antibodies in serum against both peptidoglycan and A polysaccharide reached maximum levels at 1 or 2 weeks and declined to preimmunization levels by day 63. The kinetics and magnitude of the antibody responses were similar in neonatally thymectomized and non-thymectomized rats. A relationship between chronic joint lesions and anti-peptidoglycan concentration in serum was indicated, since all rats which produced high levels of antibody developed severe chronic arthritis. However, 46% of the rats which produced very low levels of antibody also developed moderate to severe arthritis. There was no correlation between anti-A polysaccharide antibodies and joint disease, although the concentration of this antibody was 10- to 100-fold greater than the anti-peptidoglycan. We conclude that antibody can be a component in the pathogenesis of this experimental model of arthritis, but its role requires further elucidation

ARPES and NMTO Wannier Orbital Theory of LiMo6_{6}O17_{17} - Implications for Unusually Robust Quasi-One Dimensional Behavior

We present the results of a combined study by band theory and angle resolved photoemission spectroscopy (ARPES) of the purple bronze, Li$_{1-x}$Mo$_{6}$O$_{17}$. Structural and electronic origins of its unusually robust quasi-one dimensional (quasi-1D) behavior are investigated in detail. The band structure, in a large energy window around the Fermi energy, is basically 2D and formed by three Mo $t_{2g}$-like extended Wannier orbitals, each one giving rise to a 1D band running at a 120$^\circ$ angle to the two others. A structural "dimerization" from $\mathbf{c}/2$ to $\mathbf{c}$ gaps the $xz$ and $yz$ bands while leaving the $xy$ bands metallic in the gap, but resonantly coupled to the gap edges and, hence, to the other directions. The resulting complex shape of the quasi-1D Fermi surface (FS), verified by our ARPES, thus depends strongly on the Fermi energy position in the gap, implying a great sensitivity to Li stoichiometry of properties dependent on the FS, such as FS nesting or superconductivity. The strong resonances prevent either a two-band tight-binding model or a related real-space ladder picture from giving a valid description of the low-energy electronic structure. We use our extended knowledge of the electronic structure to newly advocate for framing LiMo$_{6}$O$_{17}$ as a weak-coupling material and in that framework can rationalize both the robustness of its quasi-1D behavior and the rather large value of its Luttinger liquid (LL) exponent $\alpha$. Down to a temperature of 6$\,$K we find no evidence for a theoretically expected downward renormalization of perpendicular single particle hopping due to LL fluctuations in the quasi-1D chains.Comment: 53 pages, 17 Figures, 6 year

Product Measure Steady States of Generalized Zero Range Processes

We establish necessary and sufficient conditions for the existence of factorizable steady states of the Generalized Zero Range Process. This process allows transitions from a site $i$ to a site $i+q$ involving multiple particles with rates depending on the content of the site $i$, the direction $q$ of movement, and the number of particles moving. We also show the sufficiency of a similar condition for the continuous time Mass Transport Process, where the mass at each site and the amount transferred in each transition are continuous variables; we conjecture that this is also a necessary condition.Comment: 9 pages, LaTeX with IOP style files. v2 has minor corrections; v3 has been rewritten for greater clarit

Recent Developments in the Law of the Sea IV: A Synopsis

This Article presents an annual synopsis of important events pertaining to the law of the sea which occurred between February 1, 1972, and January 31, 1973. Our major sources of information included the New York Times, the Environmental Reporter, the United States Code Congressional and Administrative News, the Congressional Record, the United Nations Chronicle, and International Legal Materials. It is our hope that the search through a seemingly endless array of indices, newspapers, microfilms, and dusty shelves will prove to be of value. We regret that the synopsis must once again report more problems than solutions, but it is with great optimism that we look to the forthcoming United Nations Conference on the Law of the Sea. Perhaps the next synopsis will report some far-reaching accomplishments of that Conference. Finally, we express our sincerest appreciation to Professor H. Gary Knight. His faith in the value of the synopsis has been a great encouragement

Non-Fermi liquid angle resolved photoemission lineshapes of Li0.9Mo6O17

A recent letter by Xue et al. (PRL v.83, 1235 ('99)) reports a Fermi-Liquid (FL) angle resolved photoemission (ARPES) lineshape for quasi one-dimensional Li0.9Mo6O17, contradicting our report (PRL v.82, 2540 ('99)) of a non-FL lineshape in this material. Xue et al. attributed the difference to the improved angle resolution. In this comment, we point out that this reasoning is flawed. Rather, we find that their data have fundamental differences from other ARPES results and also band theory.Comment: To be published as a PRL Commen

Educational Psychology in the Virtual World: A Small Study on Practice Adaptations During the COVID-19 Pandemic and Potential Benefits for Future Services

Educational psychologists (EPs) have made significant adaptations to their practice during the COVID-19 pandemic due to educational and practice restrictions in England. These adaptations, whilst facing many challenges, have also presented opportunities for growth within the profession. The current study gained a small group of EPs’ views of their experiences of working remotely through the completion of an online questionnaire. Subsequent data analysis found that EPs increased their confidence working remotely and using technology during the pandemic. The main changes reported by the participating EPs related to how they accessed clients and adapted their practice to suit remote working. Personal and professional successes were identified, and many EPs indicated it would be useful to continue some elements of remote working following the pandemic. An important area for future exploration would be to further investigate the benefits of remote working and gain the views of other stakeholders regarding their experiences of remote EP practice