10,994 research outputs found
A State-of-the-art Integrated Transportation Simulation Platform
Nowadays, universities and companies have a huge need for simulation and
modelling methodologies. In the particular case of traffic and transportation,
making physical modifications to the real traffic networks could be highly
expensive, dependent on political decisions and could be highly disruptive to
the environment. However, while studying a specific domain or problem,
analysing a problem through simulation may not be trivial and may need several
simulation tools, hence raising interoperability issues. To overcome these
problems, we propose an agent-directed transportation simulation platform,
through the cloud, by means of services. We intend to use the IEEE standard HLA
(High Level Architecture) for simulators interoperability and agents for
controlling and coordination. Our motivations are to allow multiresolution
analysis of complex domains, to allow experts to collaborate on the analysis of
a common problem and to allow co-simulation and synergy of different
application domains. This paper will start by presenting some preliminary
background concepts to help better understand the scope of this work. After
that, the results of a literature review is shown. Finally, the general
architecture of a transportation simulation platform is proposed
Densifying the sparse cloud SimSaaS: The need of a synergy among agent-directed simulation, SimSaaS and HLA
Modelling & Simulation (M&S) is broadly used in real scenarios where making
physical modifications could be highly expensive. With the so-called Simulation
Software-as-a-Service (SimSaaS), researchers could take advantage of the huge
amount of resource that cloud computing provides. Even so, studying and
analysing a problem through simulation may need several simulation tools, hence
raising interoperability issues. Having this in mind, IEEE developed a standard
for interoperability among simulators named High Level Architecture (HLA).
Moreover, the multi-agent system approach has become recognised as a convenient
approach for modelling and simulating complex systems. Despite all the recent
works and acceptance of these technologies, there is still a great lack of work
regarding synergies among them. This paper shows by means of a literature
review this lack of work or, in other words, the sparse Cloud SimSaaS. The
literature review and the resulting taxonomy are the main contributions of this
paper, as they provide a research agenda illustrating future research
opportunities and trends
Treatment of HBV HCV Co-Infection: Exceeded Response
Os vírus da hepatite B (VHB) e da hepatite C (VHC) constituem a causa mais frequente de
doença hepática crónica. A partilha de vias de transmissão contribui para o risco de coinfecção VHB-VHC. Nos doentes co-infectados com o VHB e VHC verifica-se uma progressão mais rápida para a cirrose hepática e existe um risco aumentado para o carcinoma hepatocelular.
A terapêutica da co-infecção VHB/VHC é empírica, consistindo na indicada para a infecção exclusiva pelo VHC, o qual, na maioria dos casos, é o vírus dominante. A utilização do tratamento padrão para a hepatite C, nomeadamente interferão alfa peguilado e ribavirina, não mostra diferenças significativas na resposta virológica sustentada ao VHC comparativamente
com a dos monoinfectados pelo VHC. É incerto o benefício da associação de análogos dos nucleós(t)idos.
A acção terapêutica pode modificar a interacção entre os dois vírus e, designadamente, exacerbar a doença por reactivação do VHB.
Os autores apresentam o caso clínico de uma doente com co-infecção VHB-VHC, sem
reconhecimento de vírus dominante, em que a resposta à terapêutica instituída superou a
expectativa da evidência científica disponível
Foliations and Chern-Heinz inequalities
We extend the Chern-Heinz inequalities about mean curvature and scalar
curvature of graphs of -functions to leaves of transversally oriented
codimension one -foliations of Riemannian manifolds. That extends
partially Salavessa's work on mean curvature of graphs and generalize results
of Barbosa-Kenmotsu-Oshikiri \cite{barbosa-kenmotsu-Oshikiri} and
Barbosa-Gomes-Silveira \cite{barbosa-gomes-silveira} about foliations of
3-dimensional Riemannian manifolds by constant mean curvature surfaces. These
Chern-Heinz inequalities for foliations can be applied to prove
Haymann-Makai-Osserman inequality (lower bounds of the fundamental tones of
bounded open subsets in terms of its inradius)
for embedded tubular neighborhoods of simple curves of .Comment: This paper is an improvment of an earlier paper titled On Chern-Heinz
Inequalities. 8 Pages, Late
V-like formations in flocks of artificial birds
We consider flocks of artificial birds and study the emergence of V-like
formations during flight. We introduce a small set of fully distributed
positioning rules to guide the birds' movements and demonstrate, by means of
simulations, that they tend to lead to stabilization into several of the
well-known V-like formations that have been observed in nature. We also provide
quantitative indicators that we believe are closely related to achieving V-like
formations, and study their behavior over a large set of independent
simulations
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