10 research outputs found

    Effectiveness of Sustainable Assessment Methods in Achieving High Indoor Air Quality in the UK

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    The use of sustainable assessment methods in the UK is on the rise, emulating the future regulatory trajectory towards zero carbon by 2016. The indisputable influence of sustainable rating tools on UK building regulations conveys the importance of evaluating their effectiveness in achieving true sustainable design, without adversely effecting human health and well-being. This paper reviews the potential trade-offs between human and ecological health in sustainable building design, particularly between building energy conservation and indoor air quality. The barriers to effective adoption of indoor air quality strategies in sustainable assessment tools are investigated, including recommendations, suggestions and future research needs. The consideration of occupants’ health and well-being should be paramount in any sustainability assessment method, particularly indoor air quality, thus should not be overshadowed or obscured by the drive towards energy efficiency. A balance is essential

    Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source

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    Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the Linac Coherent Light Source. The diameter of PR772 ranges from 65-70 nm, which is considerably smaller than the previously reported similar to 600 nm diameter Mimivirus. This reflects continued progress in XFEL-based single-particle imaging towards the single molecular imaging regime. The data set contains significantly more single particle hits than collected in previous experiments, enabling the development of improved statistical analysis, reconstruction algorithms, and quantitative metrics to determine resolution and self-consistency.11Nsciescopu

    1,2-Amino Alcohols and Their Heterocyclic Derivatives as Chiral Auxiliaries in Asymmetric Synthesis

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