Effects of Intravenous Aspirin on Prostaglandin Synthesis and Kidney Function in Intensive Care Patients

The effects of intravenous acetylsalicylic acid (1.0 g bolus) on renal function and prostaglandin synthesis were evaluated in a prospective, controlled study in eight patients in an intensive care unit. Four of these patients had congestive heart failure. Administration of acetylsalicylic acid caused significant antidiuresis (−56%), antinatriuresis (−82%), renin suppression (−26%) and decreased GFR (−41%). All of these changes were completely reversible within 1-2 hours and tended to be more pronounced in the patients with congestive heart failure. Urinary excretion of prostaglandin E was depressed profoundly (−93%) and did not return to more than 45% of control 6 h after the administration of acetylsalicylic acid. We conclude that intravenous acetylsalicylic acid affects kidney function in a manner similar to other prostaglandin synthesis inhibitors. Its effects are, however, short-lived. The inhibition of urinary PGE2 excretion outlasts GFR depression, antidiuresis, antinatriuresis and renin suppression by several hour

The Critical Behaviour of Potts models with symmetry breaking fields

The $Q$-state Potts model in two dimensions in the presence of external magnetic fields is studied. For general $Q\geq3$ special choices of these magnetic fields produce effective models with smaller $Z(Q')$ symmetry $(Q'< Q)$. The phase diagram of these models and their critical behaviour are explored by conventional finite-size scaling and conformal invariance. The possibility of multicritical behavior, for finite values of the symmetry breaking fields, in the cases where $Q>4$ is also analysed. Our results indicate that for effective models with $Z(Q')$ symmetry $(Q'\leq4)$ the multicritical point occurs at zero field. This last result is also corroborated by Monte Carlo simulations.Comment: 15 pages (standart LaTex), 2 figure (PostScript) available by request to [email protected]

Whole body and hepatic insulin action in normal, starved, and diabetic rats

In normal (N), 3-days starved (S), and streptozotocin-treated (65 mg/kg) 3-days diabetic (D) rats we examined the in vivo dose-response relationship between plasma insulin levels vs. whole body glucose uptake (BGU) and inhibition of hepatic glucose production (HGP) in conscious rats, as determined with the four-step sequential hyperinsulinemic euglycemic clamp technique, combined with [3-3H]glucose infusion. Twelve-hour fasting (basal) HGP was 3.0 +/- 0.2, 2.1 +/- 0.2, and 5.4 +/- 0.5 mg/min in N, S, and D rats, respectively. Next, all rats were clamped at matched glycemia (6 mM). Lowering plasma glucose in D rats from +/- 20 to 6.0 mM did not increase plasma norepinephrine, epinephrine, glucagon, and corticosterone levels. For BGU, insulin sensitivity was increased (70 +/- 11 microU/ml) in S and unchanged (113 +/- 21 microU/ml) in D compared with N rats (105 +/- 10 microU/ml). Insulin responsiveness was unchanged (12.4 +/- 0.8 mg/min) in S and decreased (8.5 +/- 0.8 mg/min) in D compared with N rats (12.3 +/- 0.7 mg/min). For HGP, insulin sensitivity was unchanged (68 +/- 10 microU/ml) in S and decreased (157 +/- 21 microU/ml) in D compared with N rats (71 +/- 5 microU/ml). Insulin responsiveness was identical among N, S, and D rats (complete suppression of HGP). In summary, 1) insulin resistance in D rats is caused by hepatic insensitivity and by a reduction in BGU responsiveness. 2) S rats show normal hepatic insulin action, but insulin sensitivity for BGU is increased. Therefore, S and D rats both suffering from a comparable catabolic state (10-15% body wt loss in 3 days) show opposite effects on in vivo insulin action. This indicates that in vivo insulin resistance in D rats is not caused by the catabolic state per se

Resonant Tunneling Between Quantum Hall Edge States

Resonant tunneling between fractional quantum Hall edge states is studied in the Luttinger liquid picture. For the Laughlin parent states, the resonance line shape is a universal function whose width scales to zero at zero temperature. Extensive quantum Monte Carlo simulations are presented for $\nu = 1/3$ which confirm this picture and provide a parameter-free prediction for the line shape.Comment: 14 pages , revtex , IUCM93-00

Classical XY Model in 1.99 Dimensions

We consider the classical XY model (O(2) nonlinear sigma-model) on a class of lattices with the (fractal) dimensions 1<D<2. The Berezinskii's harmonic approximation suggests that the model undergoes a phase transition in which the low temperature phase is characterized by stretched exponential decay of correlations. We prove an exponentially decaying upper bound for the two-point correlation functions at non-zero temperatures, thus excluding the possibility of such a phase transition.Comment: LaTeX 8 pages, no figure

Oblique Confinement and Phase Transitions in Chern-Simons Gauge Theories

We investigate non-perturbative features of a planar Chern-Simons gauge theory modeling the long distance physics of quantum Hall systems, including a finite gap M for excitations. By formulating the model on a lattice, we identify the relevant topological configurations and their interactions. For M bigger than a critical value, the model exhibits an oblique confinement phase, which we identify with Lauglin's incompressible quantum fluid. For M smaller than the critical value, we obtain a phase transition to a Coulomb phase or a confinement phase, depending on the value of the electromagnetic coupling.Comment: 8 pages, harvmac, DFUPG 91/94 and MPI-PhT/94-9

Evidence of exactness of the mean field theory in the nonextensive regime of long-range spin models

The q-state Potts model with long-range interactions that decay as 1/r^alpha subjected to an uniform magnetic field on d-dimensional lattices is analized for different values of q in the nonextensive regime (alpha between 0 and d). We also consider the two dimensional antiferromagnetic Ising model with the same type of interactions. The mean field solution and Monte Carlo calculations for the equations of state for these models are compared. We show that, using a derived scaling which properly describes the nonextensive thermodynamic behaviour, both types of calculations show an excellent agreement in all the cases here considered, except for alpha=d. These results allow us to extend to nonextensive magnetic models a previous conjecture which states that the mean field theory is exact for the Ising one.Comment: 10 pages, 4 figure

Effective electron-electron and electron-phonon interactions in the Hubbard-Holstein model

We investigate the interplay between the electron-electron and the electron-phonon interaction in the Hubbard-Holstein model. We implement the flow-equation method to investigate within this model the effect of correlation on the electron-phonon effective coupling and, conversely, the effect of phonons in the effective electron-electron interaction. Using this technique we obtain analytical momentum-dependent expressions for the effective couplings and we study their behavior for different physical regimes. In agreement with other works on this subject, we find that the electron-electron attraction mediated by phonons in the presence of Hubbard repulsion is peaked at low transferred momenta. The role of the characteristic energies involved is also analyzed.Comment: 23 pages, 5 figure