Hubungan Obesitas Dengan Tekanan Darah Dan Aktivitas Fisik Pada Remaja Di Kota Bitung

: Obesity is one of the global health problem which is often found. Indonesia is a developing country with high incident of obesity. Adolescents are the age group with high levels of obesity risk. The increasing of obesity followed by increasing co-morbidity the potential to be disease in a later time. Obesity increasing the risk of high blood pressure. Hypertension in adolescents already many found. Hypertension in adolescents is problem because it can be continued in adults. one important factor which play a role in obesity is physical activity. Objective: This research to determine the relationship of obesity with blood pressure and physical activity in adolescents in Bitung. Methodology: This study was observational analytic cross sectional design. Results: There were 60 subjekts as the subject of study that meets the inclusions kriteria which have been measured. Consisted of 21 boys and 39 girls. Of 60 obese adolescents are 34 adolescents with high blood pressure, 26 adolescent with normal blood pressure, 52 adolescent with moderate physical activity, 8 adolescents with low physical activity, there is no a significant relationship with blood pressure (Chi Square Test p=0,120), and there is no a significant relationship with physical activity (Chi Square Test: p=0,486. Conclusion: There is no a relationship between obesity with blood pressure and physical activity in adolescents in Bitung

Collapse in boson-fermion mixtures with all-repulsive interactions

We describe the collapse of the bosonic component in a boson-fermion mixture due to the pressure exerted on them by a large fermionic component, leading to collapse in a system with all-repulsive interactions. We describe the phenomena early collapse and of super-slow collapse of the mixture.Comment: 5 page

Cytokine Profiles of Severe Influenza Virus-Related Complications in Children

RationaleEffective immunomodulatory therapies for children with life-threatening “cytokine storm” triggered by acute influenza infection are lacking. Understanding the immune profiles of children progressing to severe lung injury and/or septic shock could provide insight into pathogenesis.ObjectivesTo compare the endotracheal and serum cytokine profiles of children with influenza-related critical illness and to identify their associations with severe influenza-associated complications.MethodsChildren with influenza-related critical illness were enrolled across 32 hospitals in development (N = 171) and validation (N = 73) cohorts (December 2008 through May 2016). Concentrations of 42 cytokines were measured in serum and endotracheal samples and clustered into modules of covarying cytokines. Relative concentrations of cytokines and cytokine modules were tested for associations with acute lung injury (ALI), shock requiring vasopressors, and death/ECMO.Measurements and main resultsModules of covarying cytokines were more significantly associated with disease severity than individual cytokines. In the development cohort, increased levels of a serum module containing IL6, IL8, IL10, IP10, GCSF, MCP1, and MIP1α [shock odds ratio (OR) = 3.37, family-wise error rate (FWER) p < 10−4], and decreased levels of a module containing EGF, FGF2, SCD40L, and PAI-1 (shock OR = 0.43, FWER p = 0.002), were both associated with ALI, shock, and death-ECMO independent of age and bacterial coinfection. Both of these associations were confirmed in the validation cohort. Endotracheal and serum cytokine associations differed markedly and were differentially associated with clinical outcomes.ConclusionWe identified strong positive and negative associations of cytokine modules with the most severe influenza-related complications in children, providing new insights into the pathogenesis of influenza-related critical illness in children. Effective therapies may need to target mediators of both inflammation and repair