63 research outputs found
Transcriptional regulation of early embryo development in the model legume Medicago truncatula
In the simulated postprandial state ethanol prevents insulin-dependent stimulation of mitochondrial ATP turnover: NMR study of isolated and perfused rat liver
Impact de l’utilisation d’une PCR multiplex type FilmArray ® dans le diagnostic des infections suspectées du système nerveux central à l’hôpital
Diagnosis and treatment strategies for community-acquired Streptococcus salivarius meningitis.
Neurologic Disorders in Immunocompetent Patients with Autochthonous Acute Hepatitis E
Neurologic disorders, mainly Guillain-Barré syndrome and Parsonage–Turner syndrome (PTS), have been described in patients with hepatitis E virus (HEV) infection in industrialized and developing countries. We report a wider range of neurologic disorders in nonimmunocompromised patients with acute HEV infection. Data from 15 French immunocompetent patients with acute HEV infection and neurologic disorders were retrospectively recorded from January 2006 through June 2013. The disorders could be divided into 4 main entities: mononeuritis multiplex, PTS, meningoradiculitis, and acute demyelinating neuropathy. HEV infection was treated with ribavirin in 3 patients (for PTS or mononeuritis multiplex). One patient was treated with corticosteroids (for mononeuropathy multiplex), and 5 others received intravenous immunoglobulin (for PTS, meningoradiculitis, Guillain-Barré syndrome, or Miller Fisher syndrome). We conclude that pleiotropic neurologic disorders are seen in HEV-infected immunocompetent patients. Patients with acute neurologic manifestations and aminotransferase abnormalities should be screened for HEV infection
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