Pulsation in carbon-atmosphere white dwarfs: A new chapter in white dwarf asteroseismology

We present some of the results of a survey aimed at exploring the asteroseismological potential of the newly-discovered carbon-atmosphere white dwarfs. We show that, in certains regions of parameter space, carbon-atmosphere white dwarfs may drive low-order gravity modes. We demonstrate that our theoretical results are consistent with the recent exciting discovery of luminosity variations in SDSS J1426+5752 and some null results obtained by a team of scientists at McDonald Observatory. We also present follow-up photometric observations carried out by ourselves at the Mount Bigelow 1.6-m telescope using the new Mont4K camera. The results of follow-up spectroscopic observations at the MMT are also briefly reported, including the surprising discovery that SDSS J1426+5752 is not only a pulsating star but that it is also a magnetic white dwarf with a surface field near 1.2 MG. The discovery of $g$-mode pulsations in SDSS J1426+5752 is quite significant in itself as it opens a fourth asteroseismological "window", after the GW Vir, V777 Her, and ZZ Ceti families, through which one may study white dwarfs.Comment: 7 pages, 4 figures, to appear in Journal of Physics Conference Proceedings for the 16th European White Dwarf Worksho

Carbon in Spiral Galaxies from Hubble Space Telescope Spectroscopy

We present measurements of the gas-phase C/O abundance ratio in six H II regions in the spiral galaxies M101 and NGC 2403, based on ultraviolet spectroscopy using the Faint Object Spectrograph on the Hubble Space Telescope. The C/O ratios increase systematically with O/H in both galaxies, from log C/O approximately -0.8 at log O/H = -4.0 to log C/O approx. -0.1 at log O/H = -3.4. C/N shows no correlation with O/H. The rate of increase of C/O is somewhat uncertain because of uncertainty as to the appropriate UV reddening law, and uncertainty in the metallicity dependence on grain depletions. However, the trend of increasing C/O with O/H is clear, confirming and extending the trend in C/O indicated previously from observations of irregular galaxies. Our data indicate that the radial gradients in C/H across spiral galaxies are steeper than the gradients in O/H. Comparing the data to chemical evolution models for spiral galaxies shows that models in which the massive star yields do not vary with metallicity predict radial C/O gradients that are much flatter than the observed gradients. The most likely hypothesis at present is that stellar winds in massive stars have an important effect on the yields and thus on the evolution of carbon and oxygen abundances. C/O and N/O abundance ratios in the outer disks of spirals determined to date are very similar to those in dwarf irregular galaxies. This implies that the outer disks of spirals have average stellar population ages much younger than the inner disks.Comment: 38 pages, 9 postscript figures, uses aaspp4.sty. Accepted for publication in The Astrophysical Journa

A Dark Spot on a Massive White Dwarf

We present the serendipitous discovery of eclipse-like events around the massive white dwarf SDSS J152934.98+292801.9 (hereafter J1529+2928). We selected J1529+2928 for time-series photometry based on its spectroscopic temperature and surface gravity, which place it near the ZZ Ceti instability strip. Instead of pulsations, we detect photometric dips from this white dwarf every 38 minutes. Follow-up optical spectroscopy observations with Gemini reveal no significant radial velocity variations, ruling out stellar and brown dwarf companions. A disintegrating planet around this white dwarf cannot explain the observed light curves in different filters. Given the short period, the source of the photometric dips must be a dark spot that comes into view every 38 min due to the rotation of the white dwarf. Our optical spectroscopy does not show any evidence of Zeeman splitting of the Balmer lines, limiting the magnetic field strength to B<70 kG. Since up to 15% of white dwarfs display kG magnetic fields, such eclipse-like events should be common around white dwarfs. We discuss the potential implications of this discovery on transient surveys targeting white dwarfs, like the K2 mission and the Large Synoptic Survey Telescope.Comment: ApJ Letters, in pres

Evidence for a merger of binary white dwarfs: the case of GD 362

GD 362 is a massive white dwarf with a spectrum suggesting a H-rich atmosphere which also shows very high abundances of Ca, Mg, Fe and other metals. However, for pure H-atmospheres the diffusion timescales are so short that very extreme assumptions have to be made to account for the observed abundances of metals. The most favored hypothesis is that the metals are accreted from either a dusty disk or from an asteroid belt. Here we propose that the envelope of GD 362 is dominated by He, which at these effective temperatures is almost completely invisible in the spectrum. This assumption strongly alleviates the problem, since the diffusion timescales are much larger for He-dominated atmospheres. We also propose that the He-dominated atmosphere of GD 362 is likely to be the result of the merger of a binary white dwarf.Comment: 4 pages, 3 figures. Accepted for publication in Astrophysical Journal Letter

Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes

Adhesion molecules of the integrin beta1 family are thought to be involved in the malignant progression renal cell carcinoma (RCC). Still, it is not clear how they contribute to this process. Since the hematogenous phase of tumour dissemination is the rate-limiting step in the metastatic process, we explored beta1 integrin alterations on several RCC cell lines (A498, Caki1, KTC26) before and after contacting vascular endothelium in a tumour-endothelium (HUVEC) co-culture assay. Notably, alpha2, alpha3 and alpha5 integrins became down-regulated immediately after the tumour cells attached to HUVEC, followed by re-expression shortly thereafter. Integrin down-regulation on RCC cells was caused by direct contact with endothelial cells, since the isolated endothelial membrane fragments but not the cell culture supernatant contributed to the observed effects. Integrin loss was accompanied by a reduced focal adhesion kinase (FAK) expression, FAK activity and diminished binding of tumour cells to matrix proteins. Furthermore, intracellular signalling proteins RCC cells were altered in the presence of HUVEC membrane fragments, in particular 14-3-3 epsilon, ERK2, PKCdelta, PKCepsilon and RACK1, which are involved in regulating tumour cell motility. We, therefore, speculate that contact of RCC cells with the vascular endothelium converts integrin-dependent adhesion to integrin-independent cell movement. The process of dynamic integrin regulation may be an important part in tumour cell migration strategy, switching the cells from being adhesive to becoming motile and invasive

High Carbon in I Zwicky 18: New Results from Hubble Space Telescope Spectroscopy

We present new measurements of the gas-phase C/O abundance ratio in both the NW and SE components of the extremely metal-poor dwarf irregular galaxy I Zw 18, based on ultraviolet spectroscopy of the two H II regions using the Faint Object Spectrograph on the Hubble Space Telescope. We determine values of log C/O = -0.63 +/- 0.10 for the NW component and log C/O = -0.56 +/- 0.09 for the SE component. In comparison, log C/O = -0.37 in the sun, while log C/O = -0.85 +/- 0.07 in the three most metal-poor irregular galaxies measured by Garnett et al. (1995a). Our measurements show that C/O in I Zw 18 is significantly higher than in other comparably metal-poor irregular galaxies, and above predictions for the expected C/O from massive star nucleosynthesis. These results suggest that carbon in I Zw 18 has been enhanced by an earlier population of lower-mass carbon producing stars; this idea is supported by stellar photometry of I Zw 18 and its companion, which demonstrate that the current bursts of massive stars were not the first. Despite its very low metallicity, it is likely that I Zw 18 is not a ``primeval'' galaxy.Comment: 14 pages including 4 figures; uses aaspp4.sty. Accepted for publication in ApJ. Postscript version also available by e-mail request to author at [email protected]

On the Backbending Mechanism of 48^{48}Cr

The mechanism of backbending in $^{48}$Cr is investigated in terms of the Projected Shell Model and the Generator Coordinate Method. It is shown that both methods are reasonable shell model truncation schemes. These two quite different quantum mechanical approaches lead to a similar conclusion that the backbending is due to a band crossing involving an excited band which is built on simultaneously broken neutron and proton pairs in the ``intruder'' subshell $f_{7/2}$. It is pointed out that this type of band crossing is usually known to cause the second backbending in rare-earth nuclei.Comment: 4 pages, 4 figures, accepted for publication in Phys. Rev. Let

Endoplasmic Reticulum and Mitochondria Contacts Correlate with the Presence and Severity of NASH in Humans

The interaction between the mitochondria and the endoplasmic reticulum (ER) is essential for hepatocyte function. An increase in ER-mitochondria contacts (ERMCs) is associated with various metabolic diseases. Non-alcoholic fatty liver disease (NAFLD) is associated with obesity and type 2 diabetes, and its progressive form non-alcoholic steatohepatitis (NASH) can lead to cirrhosis and hepatocellular carcinoma. However, the role of ERMCs in the progression of NAFL to NASH is still unclear. We assessed whether ERMCs could correlate with NAFLD severity. We used a proximity ligation assay to measure the abundance of ERMCs in liver biopsies from patients with biopsy-proven NAFLD (n = 48) and correlated the results with histological and metabolic syndrome (MetS) features. NAFLD patients were included according to inclusion and exclusion criteria, and then assigned to NAFL (n = 9) and NASH (n = 39) groups. ERMCs density could discriminate NASH from NAFL (sensitivity 61.5%, specificity 100%). ERMCs abundance correlated with hepatocellular ballooning. Moreover, the density of ERMCs increased with an increase in the number of MetS features. In conclusion, ERMCs increased from NAFL to NASH, in parallel with the number of MetS features, supporting a role for this interaction in the pathophysiology of NASH

High-speed Photometric Observations of ZZ Ceti White Dwarf Candidates

We present high-speed photometric observations of ZZ Ceti white dwarf candidates drawn from the spectroscopic survey of bright DA stars from the Villanova White Dwarf Catalog by Gianninas et al., and from the recent spectroscopic survey of white dwarfs within 40 parsecs of the Sun by Limoges et al. We report the discovery of six new ZZ Ceti pulsators from these surveys, and several photometrically constant DA white dwarfs, which we then use to refine the location of the ZZ Ceti instability strip.Comment: 4 pages, 1 table, 2 figures, to appear in "19th European White Dwarf Workshop" in the ASP Conference Serie