515 research outputs found
The Path to Entrepreneurship: The Role of Social Networks in Driving Entrepreneurial Learning and Education
This research aims to examine the extent to which the way entrepreneurs learn is reflected in entrepreneurship education, highlighting the existing gap between the literature on entrepreneurial learning and the practice of entrepreneurship education. To explore entrepreneurial learning in-depth, we adopted an interpretivist-constructivist approach that involves participant observation at coworking spaces and semi-structured interviews with entrepreneurs. Data were subsequently analyzed using thematic analysis. Major findings indicate that social networks play a vital role in facilitating entrepreneurial learning, with context and network serving as essential learning mechanisms. However, these elements are often disregarded in traditional entrepreneurship education approaches. This study highlights a gap in the literature where the focus of entrepreneurial learning is primarily on entrepreneurs, while entrepreneurship education primarily focuses on students and educators. The studyâs contribution is its emphasis on the importance of social networks in entrepreneurial learning and its potential for redesigning entrepreneurship education. By bridging the gap between entrepreneurial learning and entrepreneurship education, it is possible to create educational approaches that more closely mimic how entrepreneurs learn in real life, potentially leading to more impactful entrepreneurial activity
The KaVA and KVN Pulsar Project
We present our work towards using the Korean VLBI (Very Long Baseline
Interferometer) Network (KVN) and VLBI Exploration of Radio Astronomy (VERA)
arrays combined into the KVN and VERA Array (KaVA) for observations of radio
pulsars at high frequencies (22-GHz). Pulsar astronomy is generally
focused at frequencies approximately 0.3 to several GHz and pulsars are usually
discovered and monitored with large, single-dish, radio telescopes. For most
pulsars, reduced radio flux is expected at high frequencies due to their steep
spectrum, but there are exceptions where high frequency observations can be
useful. Moreover, some pulsars are observable at high frequencies only, such as
those close to the Galactic Center. The discoveries of a radio-bright magnetar
and a few dozen extended Chandra sources within 15 arc-minute of the Galactic
Center provide strong motivations to make use of the KaVA frequency band for
searching pulsars in this region. Here, we describe the science targets and
report progresses made from the KVN test observations for known pulsars. We
then discuss why KaVA pulsar observations are compelling.Comment: To appear in PASJ KaVA Special Issu
Autosomal recessive primary microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuum
Autosomal Recessive Primary Microcephaly (MCPH) is a rare disorder of neurogenic mitosis characterized by reduced head circumference at birth with variable degree of mental retardation. In MCPH patients, brain size reduced to almost one-third of its original volume due to reduced number of generated cerebral cortical neurons during embryonic neurogensis. So far, seven genetic loci (MCPH1-7) for this condition have been mapped with seven corresponding genes (MCPH1, WDR62, CDK5RAP2, CEP152, ASPM, CENPJ, and STIL) identified from different world populations. Contribution of ASPM and WDR62 gene mutations in MCPH World wide is more than 50%. By and large, primary microcephaly patients are phenotypically indistinguishable, however, recent studies in patients with mutations in MCPH1, WDR62 and ASPM genes showed a broader clinical and/or cellular phenotype. It has been proposed that mutations in MCPH genes can cause the disease phenotype by disturbing: 1) orientation of mitotic spindles, 2) chromosome condensation mechanism during embryonic neurogenesis, 3) DNA damage-response signaling, 4) transcriptional regulations and microtubule dynamics, 5) certain unknown centrosomal mechanisms that control the number of neurons generated by neural precursor cells. Recent discoveries of mammalian models for MCPH have open up horizons for researchers to add more knowledge regarding the etiology and pathophysiology of MCPH. High incidence of MCPH in Pakistani population reflects the most probable involvement of consanguinity. Genetic counseling and clinical management through carrier detection/prenatal diagnosis in MCPH families can help reducing the incidence of this autosomal recessive disorder
Agile Quality Requirements Elaboration:A Proposal and Evaluation
The increasing success and user satisfaction of agile methodsâ application in their original context (eg small co-located teams), motivated large organizations to utilize agile methods to deal with the rapidly changing markets and the distributed global workforce. Several studies have reported a variety of quality requirements (QRs) challenges in large-scale distributed agile (LSDA) context, so a recent empirical study has identified 15 QRs challenges in LSDA projects. This paper proposes an approach based on the concept of goal documentation to deal with the 15 QRs challenges reported previously. Our proposal, the Agile Quality Requirements Elaboration (AQRE) approach, introduces a new organizational role and a two-step process to elaborate high-level goals (s) into epics and user stories alongside QRs. The fitness and the usefulness of AQRE are evaluated by using a focus group with eight practitioners in the IT department of a large Dutch government organization. The evaluation indicated that 12 of the 15 QRs challenges could be mitigated by the AQRE. Our main contribution is two-fold,(i) we proposed a solution approach to deal with QRs challenges in LSDA context, and (ii) our evaluation provided empirical evidence about its usefulness in realworld context
Cerebral venous thrombosis At high altitude
Cerebral Venous Thrombosis (CVT) is one of the rarest causes of stroke. It is described as complete or partial occlusion of the sinuses or cortical veins of the brain. A relationship between high altitude (HA) and cerebral venous thrombosis has been long suspected due to various case reports and studies, however, the exact underlying mechanisms and etiologies are highly complex and debatable. In this article review we discuss the incidence etiologies, risk factors, clinical presentations and management of CVT at high altitude. CVT majorly affects young people [2]. It presents with a wide variety of clinical presentations due to the complexity of cerebral venous architecture and a combination of edema, increased intracranial pressure and venous infarct. Numerous etiologies have been suggested for the incidence of CVT; varying from dehydration, increased blood viscosity leading to endothelial injury, immobility, inflammation, genetic expression of certain prothrombotic entities, triggering of the coagulation cascade, platelet dysfunction and underlying coagulation disorders. Individuals with history of coagulation abnormalities should be screened for underlying thrombophilias and cautiously ascend to higher altitudes. CVT should be considered in all neurological clinical presentations at high altitude. High altitude trekkers should be educated on how to keep hydrated and avoid immobility, exposure to extreme cold and seeking immediate help for symptoms like headache and disturbed mental status
Ultra wideband: applications, technology and future perspectives
Ultra Wide Band (UWB) wireless communications offers a radically different approach to wireless communication compared to conventional narrow band systems. Global interest in the technology is huge. This paper reports on the state of the art of UWB wireless technology and highlights key application areas, technological challenges, higher layer protocol issues, spectrum operating zones and future drivers. The majority of the discussion focuses on the state of the art of UWB technology as it is today and in the near future
The strategic role of middle managers in the formulation and implementation of digital transformation projects
Middle managers play a crucial role in implementing digital strategy. They directly influence the success or failure of an organization's digital transformation. They are the enablers of digital strategy implementation and company transformation and sometimes can cast a sabotaging shadow side when not involved and engaged in the process. However, there are ways to engage them and divert their sabotaging behavior
The Reality of the Employees Performance in the Palestinian Cellular Telecommunications Company (Jawwal)
The aim of this study was to identify the reality of the performance of the employees in The Palestinian Cellular Telecommunications Company (Jawwal), and to find the differences between the views of the study sample on the variables of the study according to the variables (age, scientific qualification, field of work and years of service). To achieve the objectives of the study, a questionnaire was designed and developed to measure the variables of the study applied to the company's 70 employees. The Complete Census method was used and 60 samples were recovered for analysis with a recovery rate (85.7%). The SPSS statistical package was adopted. The study reached several results, the most important of which is that the degree of approval for the job performance of the employees working in The Palestinian Cellular Telecommunications Company (Jawwal) is 81.56%. The results showed that there were no statistically significant differences at the level of α†0.05 between the average of the respondents' opinions on the performance of the workers in the Palestinian Cellular Telecommunications Company (Jawwal) due to the following variables (age, scientific qualification, field of work, number of years of service). The most important recommendations were to increase the efficiency of the employees of the company using the equipment of their work, and the need to pay attention to the development of the skills of employees through specialized training programs to improve their performance. And focus on moral incentives because of their role in improving the performance of employees by spreading the spirit of cooperation between
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Contact dermatitis: one for the books
Allergic contact dermatitis (ACD) is a frequent problem, often caused from repeated exposure to an object or substance related to the patient's routine activities. We present a case of a well-demarcated, erythematous, scaly plaque on a finger caused from reading with an e-book device. Although metal from mobile devices can cause ACD, mobile device cases may cause irritation or contain additives that can also cause contact dermatitis. Similar presentations of contact dermatitis may become more common as technology use increases
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The rise in subscription skin care services
Subscription skin care services are a rising niche of direct-to-consumer telehealth models. The explosion of such services may be a reflection of the increasing demand by patients to have accessible, affordable dermatological care. These models come with both benefits and risks to patients. A thorough understanding of how subscription skin care services work may benefit dermatologists in addressing patients' questions regarding alternative care options
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