634 research outputs found

    Bipartite partial duals and circuits in medial graphs

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    It is well known that a plane graph is Eulerian if and only if its geometric dual is bipartite. We extend this result to partial duals of plane graphs. We then characterize all bipartite partial duals of a plane graph in terms of oriented circuits in its medial graph.Comment: v2: minor changes. To appear in Combinatoric

    Consensus recommendations on lymphedema in Phelan-McDermid syndrome

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    Phelan-McDermid syndrome (PMS) is a neurodevelopmental disorder caused by deletions 22q13.3 or pathogenic variants in the SHANK3 gene. Lymphedema can be a clinical feature in 10–25% of individuals with PMS due to a deletion 22q13.3, but is not observed in those with a SHANK3 variant. This paper forms a part of the European consensus guideline for PMS and focuses on what is known regarding lymphedema in PMS in order to present clinical recommendations. The mechanism causing lymphedema in PMS is unknown. Lymphedema can be suggested by pitting oedema of the extremities or, in later stages, non-pitting swelling. It can occur already at a young age and be progressive if untreated, impacting daily functioning. Lymphedema can be treated using existing general multidisciplinary management guidelines, taking the functioning of the individual with PMS into account. Furthermore, well-known risk factors for the development of lymphedema as lack of physical activities and weight gain/obesity should be addressed. Diagnosis and treatment are best performed in a multidisciplinary centre of expertise.</p

    On the Effective Action of Noncommutative Yang-Mills Theory

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    We compute here the Yang-Mills effective action on Moyal space by integrating over the scalar fields in a noncommutative scalar field theory with harmonic term, minimally coupled to an external gauge potential. We also explain the special regularisation scheme chosen here and give some links to the Schwinger parametric representation. Finally, we discuss the results obtained: a noncommutative possibly renormalisable Yang-Mills theory.Comment: 19 pages, 6 figures. At the occasion of the "International Conference on Noncommutative Geometry and Physics", April 2007, Orsay (France). To appear in J. Phys. Conf. Se

    Mechanically activated piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis

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    Mechanical forces are well known for modulating heart valve developmental programs. Yet, it is still unclear how genetic programs and mechanosensation interact during heart valve development. Here, we assessed the mechanosensitive pathways involved during zebrafish outflow tract (OFT) valve development in vivo. Our results show that the hippo effector Yap1, Klf2, and the Notch signaling pathway are all essential for OFT valve morphogenesis in response to mechanical forces, albeit active in different cell layers. Furthermore, we show that Piezo and TRP mechanosensitive channels are important factors modulating these pathways. In addition, live reporters reveal that Piezo controls Klf2 and Notch activity in the endothelium and Yap1 localization in the smooth muscle progenitors to coordinate OFT valve morphogenesis. Together, this work identifies a unique morphogenetic program during OFT valve formation and places Piezo as a central modulator of the cell response to forces in this process

    One-loop Beta Functions for the Orientable Non-commutative Gross-Neveu Model

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    We compute at the one-loop order the beta-functions for a renormalisable non-commutative analog of the Gross Neveu model defined on the Moyal plane. The calculation is performed within the so called x-space formalism. We find that this non-commutative field theory exhibits asymptotic freedom for any number of colors. The beta-function for the non-commutative counterpart of the Thirring model is found to be non vanishing.Comment: 16 pages, 9 figure

    Exorcizing the Landau Ghost in Non Commutative Quantum Field Theory

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    We show that the simplest non commutative renormalizable field theory, the Ď•4\phi^4 model on four dimensional Moyal space with harmonic potential is asymptotically safe to all orders in perturbation theor
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